AICAR can produce muscle reformation --a state influenced by gene expression (or activation), increased cellular energy and muscle fiber composition.
Two types of muscle exist: Type 1 (slow-twitch) and Type 2 (fast-twitch). Type 1 burns more fat (oxidizes fatty acids), is more resistant to fatigue -- due to an abundance of mitrochondria producing cellular energy -- and increases with endurance training.
Type 2 muscle fibers contain fewer mitrochondria, fatigues more easily, burns glucose and is commonly found in obese and sedentary individuals