Transdermal PDE5 Inhibitors

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    Question Transdermal PDE5 Inhibitors


    Hi


    Is Possible make a like:

    Tadalafil Citrate(Cialis)
    Sildenafil itrate (Viagra)
    Vardenafil (Levitra)


    maybe is not a good idea but i like to know.
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    Any reason for doing that?
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    Quote Originally Posted by Rodja View Post
    Any reason for doing that?
    no Rod only a question around my mind what do you think?
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    The MW is kinda high and they work orally. Seems pointless.
    M.Ed. Ex Phys
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    hmmmmmmm
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    No, all of them have a high molecular weight, higher than warranted for trans-dermal. Cialis is close, but still to high.

    Just go the the penis shot.... let us know how that works out for you.
    The Historic PES Legend
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    what is the MW?

    a TD formula of this enter in your bloodstream much faster than digesting a pill right?
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    Quote Originally Posted by MAxximal View Post
    what is the MW?

    a TD formula of this enter in your bloodstream much faster than digesting a pill right?
    In theory, but it's pointless. The lowest MW is ~390 for Cialis.

    I think you're missing the point of a transdermal. They're used when the oral availability is low. These drugs are definitely potent.
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    Rodja is right. You will only gain at the top end 25% product absorbtion, whilst oral is much higher than that for these products. It is much slower to enter the blood stream actually, with a slower release of upward of 12 hours. You want bang for these products, so oral is the way to go. Plus, slathering yourself up with PDE5 inhibitors then going for a naked roll in the sheets with your lady friend may not be a good idea due to transfer.
    The Historic PES Legend
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    yeap i understand guys!
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