I feel your pain...literally. When I relax my torso, my right shoulder is noticeably lower than the left one due to an S-shape in the good ol' spinal column. Like crader said, keeping your back (and core) strong will help support your spine better. You have to work with what you've got right? Muscle can act as an awesome cushion/guide for your spine.
It never affected my strength but I do injure myself more often than most b/c of the uneven nature of shear applied on my body. I have lots of pain in my lumbar/lats/rhomboid/teres on the right side because of this. Even goes up into my neck sometimes. BUT as long as I keep in shape I minimize the pain.
Don't let a physical abnormality become a mental roadblock though. If you get in a rut thinking "gee, I have scoliosis so I'm never gonna reach goal x, y and z" then it turns into a self fulfilled prophecy. Your mind can be be your own worst enemy. Don't let it!