Originally Posted by
VolcomX311
For hypertrophy (muscle size), yes. 12-8 rep range is primed, considering you're intensity is also on pair. It's not just about the volume, its the combination of volume x intensity that create a primed environment for a particular adaption (technically its the combination of Frequency, Intensity, Volume and Rest that you should take into consideration, but we'll ignore that for now)
4-6 rep range is more inclined toward strength then hypertrophy.
A general principle of resistance training, is that resistance training will have some effect on all levels of muscle adaption, power, strength, hypertrophy and endurance, but how you train will create a PRIMARY adaption of one of those aspects.
Adaption also follows that particular hierarchy of power, strength, hypertrophy, endurance. If you're performing power movements, yes you can hypertrophy, but primary adaption will be power [velocity], your secondary adaption will be strength, and your tertiary adaption will be hypertophy and lastly and least effected, but effected nonetheless will be endurance. The hierarchy also works the other way. If you're performing 20-25 reps, you're making primarily endurance adaption(s), secondary adaption will be hypertrophy, tertiary strength and lastly power
So the lower your reps in conjunction with increased weight, will move you closer to the strength zone and vice versa, the higher your reps, but still keeping a moderate intensity, the closer you move toward the hypertrophy zone on the scale of performance adaption(s).
So to answer your question in short, yes, 12-8 rep volume x's 65%-70% 1RM intensity when your on cycle. 4-6 rep volume x's 75%-85% intensity for your current program.