I've not yet ventured into a focused program, but am still making gains based on an intuitive pyramid mid-high rep style I just sorta grew into. I have a VERY loose goal going in surrounding a few compound exercises for my chosen split, then add in what I can to meet any goals I have (for example, forearms are a current focus so after I hit my bicep compounds I've been adding in a ton of reverse grip and carry work). I track my reps and sets (giving me an idea of endurance and strength over time), and as my body feels up to it I push those numbers every week. If I find I'm stuck (hasn't happened often), I shift in some new work and come back to it later. This way, I'm making both strength and hypertrophy gains (ht being the main goal).
I'd really like to follow a hypertrophy specific program like DC or MaxOT or something, but just haven't gotten a comfort level on any of them yet. As long as I'm making gains with this intuitive style training, it's all good. But I do plan on shifting into something a bit more focused.