well what i do is work out chest alone, biceps-triceps-forearms another day, back-shoulder-traps another, and legs on another. i say it comes down to what you like best.
whats your current workout routine? have you stopped seeing gains and thats why you want to change it? i mean if you really wanna try something new just TRY IT. just because your trying it doesnt mean you have to keep doing it. if u like it then stay with it. i also read somewhere that you shouldnt do split routines until you have been working out for a good while meaning a year or so but i dont know. hehe