Arzi75
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Just a thought, but I have been recently paying attention to that a lot of supp companies are adding quercetin to their supps.
I know quercetin has many uses (can be used as an antioxidant in its own etc.), but I have a feeling that a lot of these companies are adding quercetin there to make their active ingredients more powerful by providing a little CYP3A4 inhibition.
For example, I have at least 3 or 4 products in my supp cab currently that contain added quercetin (well, one being just quercetin).
I'm just worried that - and my worry might be totally unwarranted here - correct me if I'm wrong - but by adding quercetin at random to every other product, we might be forgettting that we may be putting the users of multiple supps - especially multiple pharmaceuticals - at risk because of the slowed down metabolism of ingredients that are metabolized normally by CYP3A4.
Not directing this at no one in particular, but I have seen many a company jumping on the resveratrol-quercetin band wagon lately (probably thanks to Patrick Arnold's inclusion of these in the 6-OXO Extreme as a natty test booster), but also seen many other supps not in any way, shape, or form related to any antioxidative use starting to sport quercetin on their labels.
Should these products have a note on their labels telling that "Please, note that the quercetin we have added here to make our product more potent may also be causing the other supps or medications you are taking to be more potent"?
Am I just being overly cautious about the efficacy of quercetin as a CYP450 inhibitor or should someone actually try to rein in the quercetin spree before someone gets hurt by it?
Just food for thought - I love quercetin in its own and in conjunction with some select supps, but just afraid of the ramifications of having too much quercetin in too many supps concurrently increasing their half lives beyond what might be considered healthy.
Also, the same goes for naringin, but I have not seen so widespread usage of naringin in supps, yet.
Any constructive thoughts?
I know quercetin has many uses (can be used as an antioxidant in its own etc.), but I have a feeling that a lot of these companies are adding quercetin there to make their active ingredients more powerful by providing a little CYP3A4 inhibition.
For example, I have at least 3 or 4 products in my supp cab currently that contain added quercetin (well, one being just quercetin).
I'm just worried that - and my worry might be totally unwarranted here - correct me if I'm wrong - but by adding quercetin at random to every other product, we might be forgettting that we may be putting the users of multiple supps - especially multiple pharmaceuticals - at risk because of the slowed down metabolism of ingredients that are metabolized normally by CYP3A4.
Not directing this at no one in particular, but I have seen many a company jumping on the resveratrol-quercetin band wagon lately (probably thanks to Patrick Arnold's inclusion of these in the 6-OXO Extreme as a natty test booster), but also seen many other supps not in any way, shape, or form related to any antioxidative use starting to sport quercetin on their labels.
Should these products have a note on their labels telling that "Please, note that the quercetin we have added here to make our product more potent may also be causing the other supps or medications you are taking to be more potent"?
Am I just being overly cautious about the efficacy of quercetin as a CYP450 inhibitor or should someone actually try to rein in the quercetin spree before someone gets hurt by it?
Just food for thought - I love quercetin in its own and in conjunction with some select supps, but just afraid of the ramifications of having too much quercetin in too many supps concurrently increasing their half lives beyond what might be considered healthy.
Also, the same goes for naringin, but I have not seen so widespread usage of naringin in supps, yet.
Any constructive thoughts?