[teribleturtle]

So I have been reading up on Aromatize Inhibitors such as 6-oxo and ATD, I have read on various sources that these AI’s permanently bind to and destroy estrogen. I find this to be somewhat troubling, which begs the question that perhaps some of you can help answer which is; Is the claim that they permanently eliminate estrogen true?? Does this mean that taking one 3 week cycle of say 6 oxo, ATD, or Jungle Warfare enough to eliminate estrogen forever? How exactly does it work?
I ask this because I have been shedding a considerable amount of hair and growing more body hair since March when I did a three week cycle of Jungle Warfare which contains a strong AI. I have read that these AI’s contribute to hair loss because free test is only able to convert to DHT and not estrogen any longer. I have also read that due to this hair loss is even possible in individuals not genetically predisposed to MPB (like myself). I guess my other question is, is how can I get my body to start converting some free testosterone into estrogen again? I know this question is contrary to the philosophy of many on this board but in all honesty I would much rather has my full head of hair over a lot of muscle.

[nattydisaster]

only eliminates it when you're on it. Also, most OTC AI's dont eliminate 100% of estrogen. Arimidex and aromasin are more powerful...although ATD is pretty powerful as well.

[teribleturtle]

Originally Posted by nattydisaster

only eliminates it when you're on it. Also, most OTC AI's dont eliminate 100% of estrogen. Arimidex and aromasin are more powerful...although ATD is pretty powerful as well.

Well why is it then that in the description of these products they are called suicide inhibitors the permanently eliminate estrogen, also how long after taking an AI (JW) is "normal" estrogen production to resume and DHT production/build up to decrease. Do you think taking small doses of finasteride for a few weeks would help with this?

[rpen22]

Originally Posted by teribleturtle

Well why is it then that in the description of these products they are called suicide inhibitors the permanently eliminate estrogen...?

They inhibit estrogen synthesis by permanently binding to aromatase, but the body will produce more.

[Distilled Water]

Originally Posted by rpen22

They inhibit estrogen synthesis by permanently binding to aromatase, but the body will produce more.

Yea just like when running AAS, the body stops producing testosterone but once your off it should produce more. Remember its a hormone just like testosterone. Estrogen works the same way you dont have a set number of either.

[Steveoph]

Yup, I think the confusion stems from the fact that you originally thought "AI’s permanently bind to and destroy estrogen " but what AI's do is bound irreversibly (Can't come off) to the aromatase enzyme which is responsible for the conversion of testosterone --> estrogen.

For further clarification just google Aromatase Inhibitor, there's plenty of easily accessible writing for women taking AI's like Arimidex, but the info is applicable.

[rpen22]

Originally Posted by Distilled Water

Yea just like when running AAS, the body stops producing testosterone but once your off it should produce more. Remember its a hormone just like testosterone. Estrogen works the same way you dont have a set number of either.

Uh, I guess, if that makes sense to you. That's not really the way I think about it though unless I'm misreading it. On AAS, your body stops producing T as part of a negative feedback loop. With AIs, you're inhibiting the action of an enzyme(aromatase) which is responsible for aromatizing androgens into estrogens.

[Distilled Water]

Originally Posted by rpen22

Uh, I guess, if that makes sense to you. That's not really the way I think about it though unless I'm misreading it. On AAS, your body stops producing T as part of a negative feedback loop. With AIs, you're inhibiting the action of an enzyme(aromatase) which is responsible for aromatizing androgens into estrogens.

True both do work thru difference mechanism's. I was trying to simplify it and make it more of a broad range. I have been one up'd

[thesinner]

Nothing to worry. The body naturally "washes out" the enzyme, and makes more to keep blood concentrations stable. After a few weeks of discontinuation, the body will return to normal.

Also, according to the studies done on 6-oxo, the beneficial effects begin to wain after about 4-6 weeks of use.

[jdev]

The do permanently bind to estrogen, however, your body is constantly producing estrogen. I just read the other posts. sounds like rpen said the same exact thing

About the hair, i think theres a thread by BigVrunga on it someplace with all the options for treatment for hair loss.

[teribleturtle]

My concern is basically that due to the AI my free test instead of converting to some estrogen all is converting to DHT thus causing hair loss. I read somewhere on BB.com that with AI's hairloss i possible even in individuals without genetic predisposition to to MPB due to the highly elevated levels of DHT and lack of estrogen. I also heard that drinking soy milk daily can help me out in controlling DHT due to the phytoestrogens in soy. Also any thoughts on taking finasteride at very very small doses EOD for a short time to control the DHT?

[RenegadeRows]

I don't go above 25mg of ATD per day. Any more results in libido loss for me, which says it's more powerful than we think.

[JohnnieFreeze]

Originally Posted by teribleturtle

So I have been reading up on Aromatize Inhibitors such as 6-oxo and ATD, I have read on various sources that these AI’s permanently bind to and destroy estrogen. I find this to be somewhat troubling, which begs the question that perhaps some of you can help answer which is; Is the claim that they permanently eliminate estrogen true?? Does this mean that taking one 3 week cycle of say 6 oxo, ATD, or Jungle Warfare enough to eliminate estrogen forever? How exactly does it work?
I ask this because I have been shedding a considerable amount of hair and growing more body hair since March when I did a three week cycle of Jungle Warfare which contains a strong AI. I have read that these AI’s contribute to hair loss because free test is only able to convert to DHT and not estrogen any longer. I have also read that due to this hair loss is even possible in individuals not genetically predisposed to MPB (like myself). I guess my other question is, is how can I get my body to start converting some free testosterone into estrogen again? I know this question is contrary to the philosophy of many on this board but in all honesty I would much rather has my full head of hair over a lot of muscle.

If you're not prone to "male pattern baldness" then you might have "TELOGEN EFFLUVIUM". (A rapid hair shedding from all over your head). I'm going through the same thing. I did 2 months of ATD then 2 months of a natural test booster which contains a natural estrogen suppressor (big mistake on my part as 4 months was way too long). This basically causes a shock to your hair follicles as the androgens attach to the scalp. The bad news is there isn't much you can do to stop the shedding from T.E. ..not finastide, not dutusteride.. nothing. The good news is if you stop taking the A.I.s your body will correct itself in a few months, the hair shedding will stop and your hair will grow back. You can speed up the process by using Minoxidil. It wont stop the shedding but it will make the new hair grow back faster so it wont be too noticeable while you deal with that mess.

[teribleturtle]

Originally Posted by JohnnieFreeze

If you're not prone to "male pattern baldness" then you might have "TELOGEN EFFLUVIUM". (A rapid hair shedding from all over your head). I'm going through the same thing. I did 2 months of ATD then 2 months of a natural test booster which contains a natural estrogen suppressor (big mistake on my part as 4 months was way too long). This basically causes a shock to your hair follicles as the androgens attach to the scalp. The bad news is there isn't much you can do to stop the shedding from T.E. ..not finastide, not dutusteride.. nothing. The good news is if you stop taking the A.I.s your body will correct itself in a few months, the hair shedding will stop and your hair will grow back. You can speed up the process by using Minoxidil. It wont stop the shedding but it will make the new hair grow back faster so it wont be too noticeable while you deal with that mess.

I hope that is what it is (TE), for the most part I notice shedding from all over not one specified region, however I used to have and extremely low and “closed in” hairline and widows peak, those areas seemed to have really thinned out. Now I don’t really mind that as my hairline is still rather low and closed in, what worries me is if this will continue to progress and affect the rest of the hairline. Also I was practically hair less as far as facial and body hair before taking JW I am noticing that I am now growing more body/facial hair, does this hair growth coincide with MPB?? And is that normal when taking JW or other AI’s? Also how do you know that your shedding is TE? Did you get diagnosed?
I know I ask a lot of questions but this situation has already caused a few sleepless nights and changed my whole outlook on supplements and bodybuilding in general, I appreciate all of the help and advice THANKS!

By the way I am 22 years old and still single, which is sort of why my hair and looks still matter alot to me.