Here's a post from Androgenic of MAN
I will explain how this product bothers me on an unparalleled scale. It is what is wrong with the industry. Shawn Ray uses it…hmm. This product is deceptive, trying to sound like a prohormone or even a potent steroid. The company has stated they did not decide on the name or try and be deceptive it was what the “scientist†(seriously) named it...so that's what they went with...HAHAHA! Even if they have a "scientist" of some sort, which they probably don't, that guy is not in control of their financial fate in the naming/marketing/advertising of the product.
17-HD (17-Halo-Methyl-Dianadrone): To review the choice of name here, by marketing NOT SCIENCE…let’s review.
1.)17 – As is c17a, the 17th carbon at the alpha position is where anabolic steroids have their potency and toxicity and often is where a methyl group is as attached.
2.)Halo – Besides being a great X-Box game, it is another group of steroids such as the popular halotestin, also halodrol is quite popular in the prohormone world.
3.)Methyl – See #1. Also – see buzz word of the year (#2 is ethyl ester)
4.)Dianadrone – Diana(bol) aka methandrostenolone, comes pretty close to hitting the whole 17-HD name is one fall swoop.
5.)17-HD, or 17-Halo-Methyl-Dianadrone, sounds like a chemical compound doesn’t it? Sounds like one heck of a methylated potent oral steroid. Right?
Guess what? It’s not. Matter of fact it’s just a bunch of herbs. I’d say this is pretty deceptive so far, but lets get into the useless or even counterproductive part.
Here is the ingredients according to the write-up:
17- Halo-Methyl-Dianadrone: 400mg
Ge Gan (pueraria lobota)
Smilax Officinalis
N.O. Oliliacae
Betaecdysterone 100mg
Wild yam extract 100mg
Glabra 100mg
Phosphatidyl choline 50mg
Citric acid 50mg
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We'll start with wild yam and go from there.
Wild Yam is great at regulating estrogen...there's a potent benefit! And I will quote:
"Wild yam has been used for menstrual cramps or pain, menopausal symptoms, rheumatic conditions, and gallbladder complaints. Wild yam is sometimes suggested as an alternative to hormone replacement therapy. While components of wild yam are chemically manufactured into the hormones progesterone or estrogen, the body is unable to use wild yam in the same way."
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Ge Gen is aka kudzu and I quote:
"Chemicals extracted from kudzu include isoflavones known as daidzein, daidzin, genistein, and puerarin. Isoflavones are plant chemicals that have estrogenic and antioxidant effects."
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How 'bout Smilax? Let's go for the trifecta shall we? Smilax officinalis is also known as sarsparilla.
I'll quote again...
"In the United States, sarsaparilla is sold primarily as an oral remedy for skin conditions such as psoriasis. It is believed that chemicals in sarsaparilla may attach to endotoxins (the remnants of bacterial cells) that are common in individuals with psoriasis and certain other conditions. By eliminating or reducing the amounts of endotoxins in the body, sarsaparilla may help to relieve the condition.
Orally, sarsaparilla also has weak diuretic and laxative effects, which may make it useful in promoting the loss of excess water from the body and also in treating mild constipation. It may also promote sweating, which may help to reduce fever. Additionally, sarsaparilla contains chemicals that may act as a mild expectorant – a substance that may loosen bronchial mucus and promote coughing. However, none of these effects has been verified through clinical studies and they may vary greatly depending on the amounts and type of sarsaparilla that is used. "
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Hmm...well we've established it raises estrogen, has laxative effects...is there anything else this miracle supplement can do for me you ask?
Well I am glad you asked...Glabra is cute renaming (as every ingredient is and the product itself) of Glycyrrhiza glabra, aka Licorice. Licorice you say? Yes, THE ultimate bodybuilding supplement. And I will quote:
"Licorice is also a mild laxative. Large doses of glycyrrhizinic acid and glycyrrhetinic acid in liquorice extract can lead to hypokalemia and serious increases in blood pressure, a syndrome known as apparent mineralocorticoid excess. These side effects stem from the inhibition of the enzyme 11β-hydroxysteroid dehydrogenase (type 2) and subsequent increase in activity of cortisol on the kidney. 11β-hydroxysteroid dehydrogenase normally inactivates cortisol in the kidney; thus, licorice's inactivation of this enzyme makes the concentration of cortisol appear to increase. Cortisol acts at the same receptor as the hormone aldosterone in the kidney; thus, the effects mimic aldosterone excess, although aldosterone remains low or normal during licorice overdose. Cortisol does not actually increase either; however, its activity in the kidney effectively increases due to the disabling of this enzyme. To decrease the chances of these serious side effects, deglycyrrhizinated licorice (DGL) preparations are available.
Licorice affects the body's endocrine system. It can lower the amount of serum testosterone, but whether it affects the amount of free testosterone is unclear. A PubMed search for licorice AND testosterone will provide additional information."
Well, cool, Licorice decrease testosterone, increases blood pressure and may increase catabolic hormones. Oh yeah, and again its a laxative.
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So lets tally up the results: we got elevated estrogen, decreased testosterone, increased cortisol, increased blood pressure, and 2 laxatives.
Lastly, there is one ingredient listed that, in fact, does not exist…so I can’t tell you what it is other than it is an herb. N.O. (sounds like Nitric Oxide – Buzz Word!) Olilicae. Sorry. Given the collective data one WHAT IS IN THERE, I wouldn’t hope for much.
Well the only thing of benefit I see here is the 50mg of Vitamin C (citric acid), which doesn't even meet the lowly RDA. Sweet formulation. Really.
Good luck to anyone who uses this. The supplement industry loves you.
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Shawn D. Wells, MPH, RD
Chief Scientific Officer - MAN Sports, Inc.
Soy Isoflavones lower testosterone:
