[TroubleWithin]

I'm not sure if this belongs in the Supplement Forum, so bare with me.

During my Googling, I stumbled upon MPDV and I'm curious as to why this potent CNS stimulant has not been explored as a pre-workout drug/supplement. According to the accounts I've read, by recreational users, (Haha, make of it what you will) they have had no issues with Customs, despite warnings on various websites, when importing it from the UK or Canada.

It is a norepinephrine and dopamine reuptake inhibitor, reported to be four times more potent than Ritalin (methylphenidate) and is assumed to be safer than said drug... (For the record, I didn't make this assumption, recreational users did, and I don't doubt probable long term ill-health effects, but it is an interesting compound)

I understand it to be the following:

- A CNS stimulant comparable to cocaine
- A potent aphrodisiac, moreso than methamphetamine (Due to it's dopamine reuptake inhibiting properties)
- Slightly euphoric

Has anyone, other than Nelix, had experience with this drug? Chemists, what are your thoughts?

[jjohn]

Hmm.. I ain't a chemist, but that sounds like it is a little too strong for me.. And I doubt that the use of this compound on a regular basis would be beneficial at all. Talk about elevated cortisol!

[TroubleWithin]

Originally Posted by jjohn

Hmm.. I ain't a chemist, but that sounds like it is a little too strong for me.. And I doubt that the use of this compound on a regular basis would be beneficial at all. Talk about elevated cortisol!

Yeah mate, elevated cortisol would be a problem, as with most stimulants. Apparently tolerance is developed fairly quickly too and the crash is pretty bad. I probably should of taken that into consideration before posting. Maybe someone here at AM could devise a hypothetical stack in which it would be beneficial?

[jjohn]

Well, if the crash is bad, then there would be no real use, as most stims are used during a cutting phase. I would personnaly not touch it, as like you say, the crash is bad, and this would have a tendency to eat what you aren't supposed to during this phase. So a no no for me personnaly.

[Big BAMA]

That's a little too spicy for me. I would like to still be able to function while I work out.

[jjohn]

Originally Posted by Big BAMA

That's a little too spicy for me. I would like to still be able to function while I work out.

... And not fall asleep once you're done..

[Big BAMA]

I do like the more potent than meth part. You know that's what I look for in a work out booster.

[The Paper Route]

Originally Posted by Big BAMA

I do like the more potent than meth part. You know that's what I look for in a work out booster.

lol

[TroubleWithin]

Originally Posted by Big BAMA

I do like the more potent than meth part. You know that's what I look for in a work out booster.

Hahaha, that was just one of the positive aspects of the drug, even if not in pre-workout context. I'm probably kicking a dead horse with this, i just found it interesting.

Could MDPV (half-life ~5 hours) be stacked with a stimulant that has a longer half-life, like 1,3 dimethylamylamine, (~8 hours) to lessen the crash?

As for the cortisol issue; would it be solved by including Andrenosterone in the stack? As it prevents 11beta-hydroxysteroid dehydrogenase reductase from converting cortisone into cortisol, am I correct in saying that it's mechanism of action would not have a contradictory effect on the CNS stimulation from MDPV and 1,3 dimethylamylamine?

[Chargerfball25]

This is very interesting sounding... where can i read some more about it? I think maybe like supp aimed just for CNS pre workout, not an everyday thing, might be an idea but if the crash is really bad that could be a problem.

[TroubleWithin]

Originally Posted by Chargerfball25

This is very interesting sounding... where can i read some more about it? I think maybe like supp aimed just for CNS pre workout, not an everyday thing, might be an idea but if the crash is really bad that could be a problem.

Try searching www.bluelight.ru and similar forums. I've never experienced a crash from 1,3 dimethylamylamine, so it would be an interesting stack. That said, I've never developed tolerance either, as some have reported, so I don't know...

[Sldge]

Just because some people dont crash from 1,3 dimethylamylamine doesnt mean it has a long half life or one of 8 hours. Ive never seen any research to show that it lasts that long.

Now getting back to the topic, based on structure modifications and type there is a VERY good chance MDPV would be considered an analog and would carry the same sentance weight as MDMA etc. No one having any issues yet doesnt mean they will never have any issues. If it were a more well know compound its likely that more people would have trouble.

Everyone should just keep it in mind before they start trying to order this in the US.

[jdev]

Really? this would be considered an analog? Pyrovalerone is schedule V. Are there any type of restrictions on Schedule V substances? I think it would be hard to consider MDPV an analog of MDMA as the base is completely different. Also it does not have empathogen/entactogen qualities of MDMA.

Where did you get it from? what is the effective/optimal dose?

[futrochem]

Yeah I'm a biochemist and that sounds good I would stack that with some weed and vodka before my workout though, not as a stand alone.

[TroubleWithin]

Originally Posted by Designer Supps

Just because some people dont crash from 1,3 dimethylamylamine doesnt mean it has a long half life or one of 8 hours. Ive never seen any research to show that it lasts that long.

Now getting back to the topic, based on structure modifications and type there is a VERY good chance MDPV would be considered an analog and would carry the same sentance weight as MDMA etc. No one having any issues yet doesnt mean they will never have any issues. If it were a more well know compound its likely that more people would have trouble.

Everyone should just keep it in mind before they start trying to order this in the US.

For the record, I'm in Australia and I haven't - nor do I know anyone who has - tried to import this.

Anyway, I was only using 1,3 dimethylamylamine as an exampe. I have no way of knowing how long its half-life actually is, but after reading a few forums posted with this (mis)information, I assumed that an 8 hour half-life seemed about right. I'm sure there are other substances it could be stacked with.

I am in no way, shape or form, a chemist, but if it were labelled with some sneaky/chopped-up nomenclature, as many of the better supplements are, would it squeeze past the analogue law?

When I posted this thread, I wasn't trying to convince people to purchase this compound, I was trying to offer something to the more enterprising individuals on AM.

[windwords7]

Originally Posted by Big BAMA

I do like the more potent than meth part. You know that's what I look for in a work out booster.

Yeah! LOL!