[nattydisaster]

I am picking up some P-slin and Anabolic Pump tonight. I plan on starting it as soon as I get it. But i was trying to figure out exactly what was in these supplements. I have figured out that:

Pslin:

500mg Complex
Lagerstroemia speciosa
Gymnema Sylvestre

Anabolic Pump
Lagerstroemia speciosa
Phellodendron amurense

phellodendron amurense is just a COX-2 enzyme like Glucos&Chond. Kinda weird how its used in there.

Lagerstroemia speciosa is also known as Banaba. I wonder how pure the Banaba is in both of them? And also, I wonder how much (mg) of each are in each of the supplements.

Pslin is 500mg, and AP is 750mg. My guess would be 250mg of Lagerstroemia speciosa in both, probably around 20% purity, and 250 of GS in P-slin, and 500mg Phell in AP.

Anyone with knowledge on these have any input?

[nattydisaster]

Also, if this is all thats in these two supplements, what makes them so different? the Phell or the GS? ie. What make p-slin so much better for preworkout? Also, i read in a study that bitter melon extract act almost identical to insulin in the body.

Idk...just trying to throw some ideas out there for my fellow researchers.

[CryingEmo]

I have no idea. I do know that different extracts and percentages used can be like night and day.

Case in point: The nettle root extract in activate > bulk nettle root.

[nattydisaster]

exactly...all of the ingredients in both of these can be found with the right connections to raw bulk vitamin/mineral/supplement powders.

[nattydisaster]

I also have found that 45-55% pure tannic acid is in both of them...now just trying to find out how all of this fits together...and then we could all make our own AP and P-slin.

[Cellardude]

Originally Posted by nattydisaster

I also have found that 45-55% pure tannic acid is in both of them...now just trying to find out how all of this fits together...and then we could all make our own AP and P-slin.

lmao i dont think that would make jacob very happy.

[Mulletsoldier]

Originally Posted by nattydisaster

exactly...all of the ingredients in both of these can be found with the right connections to raw bulk vitamin/mineral/supplement powders.

No, Cryingemo was alluding to the product ActivaTE being vastly superior to bulk Nettle Root.

Chinese Phellodendron Plant - along with many other indigenous Chinese plants - contains Berberine which exhibits anti-diabetic activity via AMPk activation:

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Yun S. Lee1Berberine has been shown to have antidiabetic properties, although its mode of action is not known. Here, we have investigated the metabolic effects of berberine in two animal models of insulin resistance and in insulin-responsive cell lines. Berberine reduced body weight and caused a significant improvement in glucose tolerance without altering food intake in db/db mice. Similarly, berberine reduced body weight and plasma triglycerides and improved insulin action in high-fat–fed Wistar rats. Berberine downregulated the expression of genes involved in lipogenesis and upregulated those involved in energy expenditure in adipose tissue and muscle. Berberine treatment resulted in increased AMP-activated protein kinase (AMPK) activity in 3T3-L1 adipocytes and L6 myotubes, increased GLUT4 translocation in L6 cells in a phosphatidylinositol 3' kinase–independent manner, and reduced lipid accumulation in 3T3-L1 adipocytes. These findings suggest that berberine displays beneficial effects in the treatment of diabetes and obesity at least in part via stimulation of AMPK activity.

Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK

Zhe Cheng, Tao Pang, Min Gu, An-Hui Gao, Chuan-Ming Xie, Jing-Ya Li, Fa-Jun Nan and Jia Li

National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, P. R. China


Received 17 May 2006; revised 13 September 2006; accepted 13 September 2006. Available online 20 September 2006.

Abstract

Berberine is a plant alkaloid used in traditional Chinese medicine and has been reported to have antihyperglycemic activity in NIDDM patients. However, the molecular basis for this action is yet to be elucidated. Here we investigate the effects and signaling pathways of berberine on L6 rat skeletal muscles. Our study demonstrates that berberine stimulates glucose uptake in a time- and dose-dependent manner. Intriguingly, berberine-stimulated glucose uptake does not vary as insulin concentration increases, and could not be blocked by the PI 3-kinase inhibitor wortmannin. Berberine only weakly stimulates the phosphorylation of Akt/PKB, a key molecule in the insulin signaling pathway, but strongly promotes the phosphorylation of AMPK and p38 MAPK. The effects of berberine are not a result of pro-oxidant action, but a consequence of an increased cellular AMP:ATP ratio. Moreover, berberine-stimulated glucose uptake is inhibited by the AMPK inhibitor Compound C and the p38 MAPK inhibitor SB202190. Inhibition of AMPK reduces p38 MAPK phosphorylation, suggesting that AMPK lies upstream of p38 MAPK. These results suggest that berberine circumvents insulin signaling pathways and stimulates glucose uptake through the AMP-AMPK-p38 MAPK pathway, which may account for the antihyperglycemic effects of this drug.

That explains that.

Lagerstroemia speciosa is also known as Banaba. I wonder how pure the Banaba is in both of them? And also, I wonder how much (mg) of each are in each of the supplements.

Banaba is not the term you are looking for. If you are speaking of purity, you want to know how much Corosolic and Tannic Acid our Lagerstroemia is standardized for - in that case, 15-18% and 45-55%, respectively. Glucosol, the clinical trial Corosolic Acid product, is only standardized for 1% Corosolic Acid.

Pslin is 500mg, and AP is 750mg. My guess would be 250mg of Lagerstroemia speciosa in both, probably around 20% purity, and 250 of GS in P-slin, and 500mg Phell in AP.

Anyone with knowledge on these have any input?

Nope, not even close.

P-Slin is pure concentrated Corosolic Acid, at which dosage I will not reveal. Once again, Lagerstroemia is incorrect, as we standardize for two separate constituents.

Also, if this is all thats in these two supplements, what makes them so different? the Phell or the GS? ie. What make p-slin so much better for preworkout? Also, i read in a study that bitter melon extract act almost identical to insulin in the body.

Anabolic Pump is geared more towards regulating the energy expenditure ratio of myocytes to adipocytes, working towards an aggregate shift in body composition; P-Slin, on the other hand, is exclusively tuned to the regulation of glucose metabolism, providing energy, endurance, and strength.

Bulk Banaba is and has been out there for some time - yet, I have not heard many positive reviews. My best advice would be to by both, and you will be quite surprised at the difference.

[Mulletsoldier]

Originally Posted by nattydisaster

I also have found that 45-55% pure tannic acid is in both of them...now just trying to find out how all of this fits together...and then we could all make our own AP and P-slin.

Please do! I'd be very interested in your results, or lack thereof.

[boxmeman]

Originally Posted by Mulletsoldier

Please do! I'd be very interested in your results, or lack thereof.

Dam bro your on fire tonight!

[B5150]

Thank you for the very clear definition(s) sir.

Originally Posted by Mulletsoldier

My best advice would be to by both, and you will be quite surprised at the difference.

Case in point to the OP. I am experimenting with YG/AP/PS as we speak.

They are vastly different in many aspects.

I've used AP pre workout for several weeks and liked it a lot. Took a few days to get my card count right to stave off hypo. Found the sweet spot and ran with it. Followed up post workout with AP as well.

Tried P-Slin pre work out. Same carb count. Went hypo. Needed to adjust my carbs again. Followed up with AP. No too sure I need P-Slin pre workout. I have an injury and am really not throwing a lot of weight around. I did notice improved energy and performace somewhat despite working around my injury. I did not get the infamous P-slin pump, but i did not feed it enough carbs to get it.

Now take YG. I am using it at 1-1.2 grams post workout (pre w/o p-slin). YG is not giving me that full feeling I get with AP yet it is keeping me lean, I can feel my body temp rise with carbs intake and my vascularity is insane with it. I get hungry again sooner with YG. But it is not AP nor is it p-slin. They are three different animals.

I do feel that I will find a place for all three throughout my day and week depending upon my macros and goals.

I recommend that you try them out for yourself to see the difference. It is significant. All good but all different.

[Mulletsoldier]

Originally Posted by Cellardude

lmao i dont think that would make jacob very happy.

Oh no, quite the opposite my man! Telling USP Labs, or any retailer for that matter, you are going to source their active in bulk is akin to telling Jessica Alba you're going to bang her fat sister. If Jacob saw this thread he would most likely encourage these activities, as they make our product more attractive through experience.

Dam bro your on fire tonight!

Let me clarify, as I wasn't being snide. I was and am honestly interested in nattydisaster's potential results.

Allow me to work through this. An individual like nattydisaster says:

If I can find out what % Tannic Acid and Corosolic Acid are in P-Slin and AP, I can make my own

While, on the other hand, I am thinking:

Yes, but will he enquire about what ethanol % the extract is reduced into? Will he investigate which other specific Tannins are necessary that I have not mentioned? Does he know that the soil quality (or lack thereof if harvested and cultivated hydroponically) vastly affects the quality of the extracts? Therein, does he know specific constituents of the soil in particular areas affect the molecular composition of the plant? Will he enquire about how the plant was reacted in order to standardize for each constituent?

There is this illusion out there that companies simply pluck 'any ol' extract' and throw it into a supplement - this is simply not the case. Sourcing is an ability, an art form, and a science. It does not come easy, nor cheap, and one needs to very qualitatively analyze their product.

[USPLabs]

Originally Posted by nattydisaster

I also have found that 45-55% pure tannic acid is in both of them...now just trying to find out how all of this fits together...and then we could all make our own AP and P-slin.

Knock yourself out with Tannic acid...we sport the tannins fo.

Please keep me updated on the toxic nature of your stomach after you digest 55% Tannic acid and while you’re at it you can cure some saddles and baseball mitts...researcher

[nattydisaster]

Originally Posted by Mulletsoldier

Please do! I'd be very interested in your results, or lack thereof.

Hey man, i wasn't trying to be offensive or anything, i was just trying to break these products down. There should be nothing wrong with that. This can be done with 99% of supplements if you have the ingredients. P-slin and AP are new products, so they fall under the 1% that you can't. All i was trying to do was jump start some other people into helping me find out how it could be done. There is nothing wrong with that.