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The Five Fat Loss Supplement Stack
(CLA, Lean Out, 7-KETO DHEA, Lipase Enzyme, and Taurine)

Overall, to burn fat you must accelerate your metabolism. Sitting on the couch watching TV or sitting at a desk all day is not going to allow you to achieve your fat loss goals. You need to engage in physical activity and eat a clean diet with very controlled caloric intake. Supplements can help you turn your body into a fat burning machine, and help you get the most out of the exercise you do.

#1.) CLA - One supplement that we have already discussed in chapter 3 Nutritional Supplements, section on supplementing good fats EFAs that is non-thermogenic is Conjugated Linoleic Acid (CLA). CLA is an excellent fat loss supplement.

#2.) LEAN OUT - The second supplement comes from Beverly International and is called LEAN OUT. This is a non-thermogenic supplement which helps your body burn fat, spare muscle glycogen, and reduce muscle catabolism. It contains lipotropics (substances which can liquefy or homogenize fats so that they can be burned). They increase the production of lecithin by the liver, which helps dissolve cholesterol, thus lessening cholesterol deposits in blood vessels and decreasing the chances of some types of gallstone formation, since many gallstones are made of cholesterol. It also prevents the accumulation of fats in the liver. LEAN OUT increases resistance to disease by helping the thymus gland carry out its anti-disease functions of producing antibodies, phagocytes that fight against microbes and viruses, and destroy abnormal tissue. The following are some of the key ingredients in LEAN OUT: choline, inositol, methionine, L-carnitine, chromium picolinate, and co-enzyme 10 (Co-Q-10).
 Choline metabolizes fats; a deficiency in this element can lead to cirrhosis, fatty degeneration of the liver, and hardening of the arteries (arteriosclerosis and artherosclerosis). It is used for ailments such as gall bladder trouble, diabetes, Muscular Dystrophy, glaucoma, arteriosclerosis, senility, and memory problems such as forgetfulness. It detoxifies amines, which are byproducts of protein metabolism.
 Inositol deficiency can lead to hair loss; it works with Vitamin E to help treat Muscular Dystrophy, and in nerve and muscle disorders such as Multiple Sclerosis and Cerebral Palsy. Caffeine can cause depletion of inositol.



The author before and after. Left photo by Kathleen Ryan. Right photo by Eric Beach.

 Methionine works with choline to detoxify amines by acting as a catalyst for choline and inositol. Along with choline, methionine aids in reducing liver fat and protects the kidneys.
 L-Carnitine is a derivative of the amino acids lysine and methionine. It is mainly synthesized in the liver and kidneys, and then transported for use in tissues in the body. One of the key uses of acetyl L-carnitine is for fatty acid oxidation. Fatty acids are an important energy source for the body. Through oxidation, fats are broken down to create energy. Carnitine plays a role in energy production. It is found in many foods, including meats, vegetables, and grains. The body can produce some L-carnitine on a daily basis, with the highest concentrations found in the heart and skeletal muscles. Deficiencies are rare. Acetyl L-carnitine side effects are also rare, and include increases in blood pressure, faster heart rates, fever, and diarrhea. L-carnitine helps in energy production, weight loss, and burning fat, enhances cellular energy in the brain to improve mental performance, and can decrease symptoms of depression. It helps prevent cataracts as well.
 Chromium picolinate increases the efficiency of insulin to optimal levels. After eating, the body secretes the hormone insulin to transport glucose to the body’s cells in order to provide energy. It is thought that chromium picolinate helps the body’s glucose and fat metabolism by managing their breakdown and preventing excess fat from forming.
 Co-enzyme 10 (Co-Q-10) is a fat soluble antioxidant which protects lipid-soluble substances such as cholesterol from being deposited on the walls of arteries. For further information refer to the “Antioxidants” section.

#3.) 7-KETO DHEA - This fat loss supplement does not have a thermogenic effect on the body. This product is sometimes combined with stimulants in a stack. If you wish to avoid stimulants, make sure that you read the supplement product label.
Its usefulness in weight loss was discovered in the 1990’s by researchers at the University of Wisconsin. In 2007, Humanetics corporation received a patent from the United States Patent and Trademark Office. 7-Keto®, received the patent for modulating the basal metabolic rate & effecting weight loss when administered in combination with a diet. Taking 7-keto in dosage levels recommended by the manufacturer should not cause adverse effects, even for extended periods of usage (up to three months).
7-Keto DHEA is not the same as DHEA, but it is a metabolite of DHEA. The body converts DHEA into 7-Keto DHEA. 7-Keto DHEA is used to help lose body fat and balance thyroid function. Other benefits include strengthening the immune system, increasing IGF-1 hormone production, relieving depression, and increasing energy. A very important benefit is that it helps overcome insulin resistance. It also helps reduce cortisol hormone levels.

How is 7-Keto DHEA different from DHEA? 7-Keto DHEA is already converted from DHEA, so it will not have the negative effect of increasing estrogen or testosterone hormone levels like DHEA does. There are no known side effects of 7-Keto DHEA.

7-Keto DHEA and the Thyroid
7-Keto DHEA helps the body lose weight by stimulating the liver with enzymes that make the body increase the amount of calories burned. Essentially, 7-Keto DHEA increases metabolism by increasing T3 (triiodthyronine) thyroid hormones.

What is the body’s “set point” and how can I change it?
One of the biggest challenges to weight loss is your body’s own “set point” (or point of metabolic adaptation, the body’s preferred weight). Due to the effects of the set point, people who go on a crash diet often gain back the weight that they had lost. One of the biggest challenges to weight loss is the body’s desire to slow down its metabolic rate despite attempts to lose weight.
As you get older, this set point increases. The theory is that metabolism adjusts to maintain the body’s preferred weight. If weight is lost too fast, the body thinks it is being starved and slows the metabolism to stop from losing additional fat. Taking 7-Keto DHEA keeps the metabolism elevated, and allows for a lower set point. Consequently, the body can maintain weight loss without strong cravings for additional calories that would lead to weight gain. Once you have reached your goal weight, you should stop taking the supplement.
Avoid crash dieting by not losing more than two to three pounds a week. When you lose too quickly, the body will respond as if you are starving it.
Some of the supplements sometimes used in conjunction with 7-Keto include green tea, guarana extract, hoodia gordonii, bromelain, and grapefruit extract. They are discussed below.
 Green tea is an antioxidant that helps improve the body’s usage of fat as an energy source.
 Guarana extract comes from the seeds of a South American shrub often found in Brazil. Guarana functions as an effective energy booster since it contains approximately twice the caffeine (xanthines) found in coffee beans (about three to four percent caffeine in guarana seeds as compared to one to two percent for coffee beans). Concentrated guarana extracts, however, can contain caffeine at levels of as much as 40-50%. Refer to the section on “Stimulants” for more information.
 Hoodia gordonii is a succulent from the Kalahari Desert in southern Africa. It is used as a natural appetite suppressant, so it has the affect of reducing your interest in food, delaying the time after eating before hunger sets in, making you feel full more quickly, and providing a general feeling of well-being. It is not a stimulant, and has no known side effects.
 Bromelain, a general name for a family of sulfhydryl proteolytic enzymes, is found in high concentrations in pineapple stems. Bromelain is useful for many conditions including improved digestion. It is also very effective in relieving inflammation caused by infection and physical injuries. The protein-digesting enzymes found in bromelain help digestion and might relieve upset stomach and heartburn. Its affects are enhanced when it is used with other enzymes, for example lipase, which digests fat. It might also help control diarrhea caused by bacteria. It is generally recommended that bromelain not be taken in large doses for longer than 8 to 10 days. Side effects include nausea, vomiting, diarrhea, and excessive menstrual bleeding. Individuals who are allergic to pineapples should not take bromelain since it could cause skin reactions and/or asthma-like symptoms. Pregnant women, people with bleeding disorders, high blood pressure, or liver or kidney disease, or individuals taking antibiotics or blood thinning medications should consult a healthcare provider before taking bromelain.
 Grapefruit Extract helps curb appetite and improves fat metabolism.

#4.) Lipase Enzyme Supplements
Lipase is a digestive enzyme used by the body for absorption and digestion of nutrients in the intestines. It breaks down triglycerides (for further information see chapter 3 nutritional supplements, supplementing good fats (EFAs). After they are broken down, triglycerides are more easily absorbed in the intestines. Lipase is mainly produced in the pancreas but is also produced in the mouth and stomach. Most people produce sufficient amounts of pancreatic lipase. However, given the demands of a fat loss diet, supplementation might be of benefit in processing fats. Pancreatic enzyme supplements help the body absorb food more easily. Lipase and other pancreatic enzymes reduce bloating and gas after high-fat meals. It is also believed that irritable bowel syndrome can be relieved with the use of pancreatic enzymes. There are no known side effects from lipase or other pancreatic enzyme supplements. However, do not take lipase supplements if you are taking Orlistat, a medication used to treat obesity that blocks the ability of lipase to break down fats.

#5.) Taurine
This helps strengthen heart function and helps in the digestion of fats and absorption of fat-soluble vitamins.

TIP
When attempting to lose fat the metabolism can pose a challenge by slowing down and halting progress in achieving your goals. Your metabolic rate also slows naturally with age, as well as with reduced calorie intake. Along with adjustments to your nutrition and workout plans, I recommend the use of fat loss supplements CLA, Lean Out, 7-Keto, and Taurine. These are extremely effective at breaking through plateaus in fat loss when combined with a phased calorie reduction nutrition plan and physical activity including aerobics. I also recommend taking additional L-Carnitine prior to physical activity. You might also decide to try lipase enzyme supplements to improve the digestion of fats.