Has anyone tried very high doses of eurycoma? I've heard up to 3g, but what about 4, 5, 6g+? I've read it seems to be dose-dependent, but is this tolerable?
3 g of what ?Has anyone tried very high doses of eurycoma? I've heard up to 3g, but what about 4, 5, 6g+? I've read it seems to be dose-dependent, but is this tolerable?
Just something more to consider.
LJ100 vs. LongJax 20:1
LJ100 is a Eurycoma product that is a 100:1 water extract. They recently have standardized their product based on Europeptide. They had a patent application filed on that. I have read carefully the patent application (US 2004/0087493). I am not convinced that the peptide they identified, 36 amino acids, 4.3KD is responsible for the biological activity for the following reason:
A) The only biological test they did in the patent application was using a Fr3 fraction by size-exclusive column. This faction contains many things, among them the 36 amino acids, 4.3KD peptide. Based on my many year’s experience in drug-based screening, unless you purify the peptide or synthesis the peptide and use it for the biological testing, you can not conclude at all that the peptide is responsible for the effect. IN fact, 98% of the cases it is not responsible.
Based on my experience, peptide normally elute at 20-40 mins range. 9 mins elute is too early for peptide, which makes me skeptical.
C) If you look at the HPLC graph on Figure 3 of the patent application, there are many different components there. Unless they specifically tested the peptide (which did not show in the patent), they can not conclude that the peptide is responsible for the biological effect.
Unless they have direct data, Europeptide is misleading to me.
2) Lab Analysis
If they believe that it is the glycoprotein that is responsible, our product has high content of glycoprotein, even at a 20:1 ratio. Here is the result of our LongJax versus LJ 100 done at the same independent lab:
Based on the Glycoprotein level, our product provides 10 fold more value compared to LJ100 since their product is 5 times more concentrated. This is conceivable because optimal extraction concentration will likely retain more useful ingredients.
3) Human Studies:
The optimum test of the biological function is, of course, the effectiveness in human. We have also carried a small human test, and fortunately, used the same method as done by LJ100. Thus it can be used as a comparison.
1) LJ100 study (copied from Website)
Saliva Testosterone Test of 9 Individuals 26-52 years of Age
¢Dosage 2x2(50mg/capsules) morning & evening for 10 days
¢Normal range for athlete 800 = 150ng/dl of blood
Volunteer age pre treatment after treatment %
ng/dl blood ng/dl blood Increase
1 26 860 = 30 1,650 = 50 91.86%
2 28 580 = 30 985 = 35 69.83%
3 35 875 = 40 1, 576 = 60 80.11%
4 24 950 = 45 2,210 = 55 132.63%
5 29 755 = 30 1,345 = 35 78.15%
6 48 650 = 20 875 = 30 34.62%
7 52 450 = 25 765 = 35 70.00%
8 50 585 = 25 875 = 35 49.57%
9 42 350 = 30 480 = 35 37.14%
Data – preliminary data - more work to be carried out
Volunteers 1-5 are athletes - data are an average of 3 different studies at different times
Volunteers 6-9 do not exercise on a regular basis
2) Longjax study
Testosterone Saliva Test
(Dosage 800mg/day for 5 days)
Volunteer Age Pre-treatment After-treatment % increase
(ng/dl) (ng/dl)
__________________________________________________ _______
1 61 49.9 130.9 150%
2 40 147 274 86%
3 25 181 334 85%
__________________________________________________ _______
*Tests were done in the US by medical clinical labs.
*Samples were collected same time every morning.
*Preliminary data
* Volunteers do not exercise on a regular basis.
Notice that in normal individuals, LJ100 at 200mg/day (100:1 extract) increased T on an average 47.83% in four individuals. Longjax, on the other hand, increased T on an average 107% in three individuals at a dosage of 800mg/day (20:1 extract). Thus, LongJax is 2-fold effective in human tests even at a lower dosage as compared to LJ100.
4) Safety Issue:
Longjax has a LD50 of greater than 5g/kg (the highest people normally test). We spent more money to have the test done in Japan to insure quality.
5) Other Quality Advantages of Longjax
A. We set internal quality control standards. We take steps to make sure our quality is consistent. B. We do studies in the US to assure accuracy.
C. LongJaX is reprocessed in the US. As a result, it offers the following three advantages.
a) Free flowing and friendly for manufacturing.
The eurycoma extract tends to be clumpy when stored over a period of time. The capsule may not look the same as the new ones. LongJaX can store much longer without the same issue. Your capsules can maintain its original form over time.
c) The eurycoma extract can have high yeast and mould. The reprocessing process will help control yeast and mould.
d).Our material is made of roots. There are inferior materials on the market that are made of trunk. Such extract may have low potency and high toxic ingredients
If the study is indeed accurate and not biased...then the puffiness may be a result of increased aromatization. Using an AI like androstenetrione/6-OXO would help.Chain, I get really huge on this stuff, but puffy huge, including my face ( not kewl with the ladies ) , almost like a panax ginseng puff.... not sure how to manage, so I go off.... this happen to you at all ??? I wouldn't say it's gyno / water retention, just not sure WTF it is..... makes my libidocrazy, tho ( LJ100 )
tks.... I got some 6 OXO too.... apparently, they just made it illegal up here in Canada....If the study is indeed accurate and not biased...then the puffiness may be a result of increased aromatization. Using an AI like androstenetrione/6-OXO would help.
tks.... I got some 6 OXO too.... apparently, they just made it illegal up here in Canada....
Erm.. cabergoline is hard to get and suppresses HGH.I just read another thread and apparently the side effects you are experiencing may be from increased prolactin. If this indeed is the case, you would want to use dopaminergics like cabergoline to mitigate the negative side effects.
Concentration ratio is irrelevant, as the active components are unknown and might very well be lost in a "stronger" concentrate.this is a really noobie question and i feel dumb for asking because it still confuses me but can someone explain how the ratio extract thing to me so i know im right in my thinking. i mean how this stuff is to be interpreted: 20:1, 100:1, 50:1, and LJ100. i would think 100:1 is the best ratio but it seems like that thought is incorrect. anyone please help me understand?
thanks for the responseConcentration ratio is irrelevant, as the active components are unknown and might very well be lost in a "stronger" concentrate.
The root has 2% of soluble material, so 50:1 makes most sense.
levodopa is legal? is it a research chem?Erm.. cabergoline is hard to get and suppresses HGH.
Levodopa is freely available as Mucuna Pruriens, stimulates HGH and still has the dopaminergic sexual effects
But I have not had any side effects from the Indonesian 200:1 or 50:1.
Herbal levodopa is definitely legal and also more effective than synthetic.levodopa is legal? is it a research chem?
i read your original post wrong. i thought you meant you can actually get the synthetic stuff which would be levadopa, the herbal stuff is not actually levadopa, its just mp. but thanks for the reply.Herbal levodopa is definitely legal and also more effective than synthetic.
If you want to use it for research instead of just taking it, then well, be my guest
does not surprise me one bit.By the way, I noticed absolutely nothing on even up to 6g a day of the SciFit Eurycoma. Junk.
I understand that Mucuna extract contains levodopa and is often standardized to a specific levodopa content. And it appears to be more potent, with lesser side-effects than the synthetic levodopa, according to the studies I've read.i read your original post wrong. i thought you meant you can actually get the synthetic stuff which would be levadopa, the herbal stuff is not actually levadopa, its just mp. but thanks for the reply.
Blind12,...But I have not had any side effects from the Indonesian 200:1 or 50:1.
I'm not going to mess with Eurycoma again until I can find out a source that is definitely a good product and at a reasonable price. The Nutraplanet stuff for example would cost $25 for 10 days worth at 3g/day. At 20:1 I'm not sure what dose would be needed for the effect. There seems there is no consensus on what the best extract is, but the people from Indo were supposed to use 50g of the root, so a 50:1 extract would mean 1g would equal the 50g root dose. A good dose is 1-3x this. If that's true then the 20:1 from NP would be horrifically expensive to use.
Also the Indo people were supposed to boil the root quite extensively, and this has also been used in studies showing its effectiveness. So I'm not sure even how this works with extracts. I've even read that the active is fat soluble, so I'm confused and honestly losing interest in really trying to straighten things out, especially considering the estimated cost for good doses.
Nothing too obvious. Seemed to work sometimes and sometimes not. Generally libido, strength, recovery and physical energy seemed up. And body smell seemed different.Blind12,
what kind of results did you see from the 200:1 extract and how much were you taking?
It could be me, not their processThanks for that info. blind12..if the 200:1 extract only worked sometime than I'd bet that their extraction process is faulty...maybe the LJ100 people who say they have a patented extraction process are on to something...hmm...
It could be me, not their process
The lows were often at times when I'd be naturally low - cold, rainy, stressful days.
The Indonesian extraction process is very simple of course, but the one used in posted studies of LJ100 was equally simple. No special conditions to protect the actives, plain water extraction etc.
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