[MESSPLAY]

Is this the real deal? I found a website that is pre-selling the new AA+NO supplement that was fused by a licensing agreement between Axis Labs and Molecular Nutrition. Has this already hit shelves?





If this is information that is NOT supposed to be shared, would a mod please delete this post accordingly.

Or if this information has already been posted, please bash me.

[nunes]

I don't see nothing new in the ingredients profile .
For me it`s a product that I pass , the AA gives me headaches.

[MESSPLAY]

what I'm wondering is if while on hemodraulix, you'll need to alter your diet like you were on x-factor, or if the AA isn't as potent in this blend

[nunes]

Originally Posted by MESSPLAY

what I'm wondering is if while on hemodraulix, you'll need to alter your diet like you were on x-factor, or if the AA isn't as potent in this blend

I`m almost sure that you have to alter your diet .
If it got AA , you must follow AA rules...

[MESSPLAY]

Yeah that sounds reasonable. I don't really quite understand the synergy between AA and NO. How does AA react with the body during exercise?

[strategicmove]

Originally Posted by MESSPLAY;

Is this the real deal? I found a website that is pre-selling the new AA+NO supplement that was fused by a licensing agreement between Axis Labs and Molecular Nutrition. Has this already hit shelves? ---
If this is information that is NOT supposed to be shared, would a mod please delete this post accordingly.

Or if this information has already been posted, please bash me.

It would be disappointing if HemodrauliX is already been pre-sold elsewhere and we at AM did not get a chance to grab some!

[nunes]

Originally Posted by MESSPLAY

Yeah that sounds reasonable. I don't really quite understand the synergy between AA and NO. How does AA react with the body during exercise?

AA is a vasodilator too , maybe axis try to catch 2 ways of increasing blood flow into muscles, interesting that I saw in other threads some reps from MN saying that you dont need NO products when using AA because the vasodilation can`t get any better, maybe axis dont think the same way...

[MESSPLAY]

Originally Posted by strategicmove

It would be disappointing if HemodrauliX is already been pre-sold elsewhere and we at AM did not get a chance to grab some!

if you want the link throw me a pm brutha!

[strategicmove]

Originally Posted by MESSPLAY;

Yeah that sounds reasonable. I don't really quite understand the synergy between AA and NO. How does AA react with the body during exercise?

Nitric oxide is involved in arachidonic acid synthesis, amongst others. Elevation of nitric oxide activity in endothelial cells would not only produce vasodilation and other outcomes, but would also lead to elevation of arachidonic acid synthesis. A blend with advanced arginine forms may not require a huge dose of arachidonic acid, as the synergy would spare huge doses of arachidonic acid.

The following study may help.

Regulation of cyclooxygenase enzymes by nitric oxide.

Nitric oxide (NO), derived from L-arginine (L-Arg) by the enzyme nitric oxide synthase (NOS) is involved in the regulation of several important physiological and pathophysiological functions. The mechanisms by which NO exerts some of its beneficial or detrimental effects include activation of guanylate cyclase, formation of peroxynitrite, apoptosis, and regulation of cyclooxygenase (COX). Cyclooxygenase (COX) is the enzyme that converts arachidonic acid to prostaglandins (PG), prostacyclin (PGI2) and thromboxane A2. The role of NO in the regulation of COX and its importance in physiology, pathology and therapy will be reviewed. Evidence will be presented to suggest that COX enzymes are targets for the physiopathological roles of NO and that once activated in the presence of NO, they represent important transduction mechanisms for its multifaceted actions.

Authored by Salvemini D. Discovery Pharmacology, G.D. Searle Co., St. Louis, Missouri 63167, USA.
Published in Cell Mol Life Sci. 1997 Jul;53(7):576-82

[MESSPLAY]

Always helpful guys. Strategic, what are the benefits PG and PGI2 ? Or is it the energy of the conversion that is beneficial

Sorry, I'm trying to soak up as much information as possible.

[strategicmove]

Originally Posted by MESSPLAY;

Always helpful guys. Strategic, what are the benefits PG and PGI2 ? Or is it the energy of the conversion that is beneficial

Sorry, I'm trying to soak up as much information as possible.

They are basically part of arachidonic acid's inflammatory pathway. More specifically the arachidonic acid cascade involves 5-LOX (5-Lipooxygenase), COX-1, and COX-2.

5-LOX (5-Lipooxygenase) is an enzyme that is produced in higher amounts by the body in response to an overload of arachidonic acid. 5-LOX functions to degrade arachidonic acid. However, 5-LOX directly stimulates the propagation of cancer cells. Furthermore, 5-LOX produces breakdown products from arachidonic acid. These products, leukotriene B4, 5-HETE, and hydroxylated fatty acids, motivate tissue destruction, chronic inflammation, as well as the increased resistance of tumor cells to apoptosis or programmed cell destruction.

Apart from 5-LOX, the body produces other dangerous enzymes such as cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) that participate in the breakdown of arachidonic acid.

COX-1 leads to the production of thromboxane A2. Thromboxane can enhance abnormal arterial blood clotting or thrombosis, leading to heart attack and stroke.

COX-2 participates directly in cancer cell propagation. Its breakdown product, prostaglandin E2 fosters chronic inflammation.

[strategicmove]

I just wanted to add that HemodrauliX, due to its nitric-oxide-arachidonic acid blend, will definitely be the first arachidonic-acid product I will use. It is definitely a unique and refreshing blend that goes well beyond the usual NO-type products. I am really looking forward to it .

[LatSpread]

I would prefer to just stack BA and Xfactor together (rather than pay near 50$ for argenine and small amounts of BA and Arachadonic Acid).

[wontdie]

alright, I'd be adding bulk Arginine to my bulk X now.