I've been taking picamilon for about a week now 100mg 2 times a day and feel no effect from it as far as reducing my anxiety how long does this stuff take to kick in? does it work for everyone? has anyone tried mixing it with phenibut?
It is not clear how you currently take your picamilon. On an empty stomach or with meals? Anyway, Picamilon is best absorbed on an empty stomach between meals. The effects of Picamilon usually set in fast, often within an hour. The half-life of the agent maintains the effects for about six or so hours. So, I would recommend you split your doses into three, rather than two, so the effects are better spread throughout the day. Avoid dosing picamilon in the evening to avoid possible insomnia.
In terms of duration of supplementation, best results are obtained between one week and about six weeks, as the effects are cumulative.
Picamilon has, by the way, very low toxicity. The median lethal dose is more than 10g/kg of body weight, and more than 6g/kg of body weight if administered intravenously.
