[jjohn]

This is from the CAMBRIDGE INTERNATIONAL INSTITUTE FOR MEDICAL SCIENCE

Please take the time to read all of the article as it is very informative and you will ever see the EFA's the sama way again!

http://www.brianpeskin.com/efa-analysis.pdf

Omega-3’s derivative PGE3 isn’t nearly as powerful or as effective as
Omega-6’s PGE1. The function of omega-6 and its derivatives like AA (arachadonic
acid) is to prevent, not cause inflammation (unless required by the
body to seal a wound). The mistake often made by researchers is the assumption
that increased AA automatically increases PGE2—an inflammatory. This
assumption is incorrect because the body manufactures PGE2 AS NEEDED.
All EFA derivatives are manufactured as needed and this is no exception.

Arachadonic acid is anything but harmful: AA is the precursor to prostacyclin—
the most potent anti-aggretory agent (a natural “blood thinner”)
28
The Scientific Calculation of the Optimum PEO™ Ratio
and inhibitor of platelet adhesion.18 AA contributes to smooth working of
vascular function and blood flow. AA provides eicosanoids for response to
injury—acting as a healer—helping to seal the wound. It is critical.


overdosing on omega-3 can lead to profuse
internal bleeding from eicosanoid overproduction!

“ In practice, AA is a major component of the endothelial [inner
arterial lining] phosphoglycerides, particularly on the inner cell
membrane layer. AA and adrenic acid are consistent companions
in other cell membranes. It is the precursor for prostacyclin: a
vasodilator and inhibitor of platelet adhesion.
“…AA acts as contributor to the smooth working of blood flow
and vascular function.”
“… If there is damage to the endothelium, such as in bruising,
infection or cutting, then the phospholipases release AA. In the free
form, and in conjunction with activated platelets, AA is peroxidized
to provide eicosanoids for the response to injury.
“Thus, they [AA] contribute to vasoconstriction and thrombosus to
seal the wound. Without this response we would be in trouble.” The
same principle applies to the inflammation response which again is
much needed for survival. AA is anything but the dark side.
“… The problem is that certain chronic disease conditions such
as arthritis and ischemic heart disease, the damage already done,
results in chronic stimulation of this response to injury… This is
not the fault of AA or DGLA, but of the original cause of damage
….” (Emphasis added.)

AA is critical. Don’t let anyone tell you that parent omega-6 causes a
“problem” in excess AA production. Arachidonic acid (AA) is a critical biochemical
component, and occurs in virtually every cell we have! It is the
building block of the most potent anti-aggretory (“helps blood thinning”)
agent known (prostacyclin). This omega-6 derivative also inhibits platelet
adhesion (a natural “blood thinner). AA helps SOLVE vascular problems as a response to injury in a fashion like cholesterol. So once again, just like
cholesterol, the “problem solver” is incorrectly blamed as the cause of the
problem. There is always a balance between opposing forces. For example,
one biological substance increases blood pressure and another one decreases
blood pressure. Even though we frequently hear the terms good and bad,
there is no “good” or “bad.” There is only complementary function. We must
ensure our bodies have enough biochemical substances to ensure both effects
can be carried out automatically.

[metroba]

good info.

[jjohn]

good info.

Gold. lol

[Dancebot 2000]

All right, I get it. I'll buy your damn X-factor.

[ImJ2x]

jjohn is, like the best salesman ever.

[jjohn]

This is just to inform you guys that AA is not evil. Please take some time to read it and you'll be surprised!

[strategicmove]

This is just to inform you guys that AA is not evil. Please take some time to read it and you'll be surprised!

AA is definitely not evil. And, by the way, I admire your drive to clean up the possible misconceptions about AA and X-Factor. If only some other company reps would do close to half the same for their products.

[jjohn]

AA is definitely not evil. And, by the way, I admire your drive to clean up the possible misconceptions about AA and X-Factor. If only some other company reps would do close to half the same for their products.

I kindly thank you for that! Thanks very much. Also, we have to consider that the MN reps have a lot of time to study and research AA, as it is (for now) the only supplement we produce. Some companies have products coming out every week it's harder to follow on these lol.

[Dancebot 2000]

Although I'm pro X-factor and am trying to buy some now, I don't think this report is really refering to mega dosing AA.

[jjohn]

Although I'm pro X-factor and am trying to buy some now, I don't think this report is really refering to mega dosing AA.

This has nothing to do with mega dosing AA. It just clearly indicates you that AA is beneficial for oxygenation in the muscle cells, prevents lactic acid buildup, and a lot more benefits.

[rpen22]

Although I'm pro X-factor and am trying to buy some now, I don't think this report is really refering to mega dosing AA.

That's what I was thinking. I didn't think anyone was saying that Arachidonic Acid wasn't beneficial in the body. Of course it's important, but that's not saying you need supplemental high doses.

[jjohn]

That's what I was thinking. I didn't think anyone was saying that Arachidonic Acid wasn't beneficial in the body. Of course it's important, but that's not saying you need supplemental high doses.

Talk to any nutritionist, most (probably all) of them will say avoid AA at all costs. They will limit your egg intake because of AA. And that's no joke.

AA has been shown to be significantly higher in obese people, and nutritionists say (think) that there is a correlation with this and blod clotting, and that's absolutely false. This was oe of my points when posting this article.

And by the way, if you supplement with AA 1-2 caps a day, you can use this long term as well. So 1 gram is not that high of a dose, and is completely safe and effective.

[rpen22]

Trust me, I know. I'm in a nutrition course. I realize that's what the author was targeting with this. They are associating the inflammatory response from AA with the higher rates of cardiovascular disease in people on a Western Diet.

I'm not saying either one is right or wrong, I'm just saying that that report didn't sound like it was exactly condoning supplemental AA, IMO.

Edited.

[strategicmove]

Trust me, I know. I'm in a nutrition course. I realize that's what the author was targeting with this. It's because most people on a Western diet's n-6:n-3 ratio is close to, I believe, 4:1 and should apparently be closer to 1:1. They are associating the inflammatory response from AA with the higher rates of cardiovascular disease in people on a Western Diet.

I'm not saying either one is right or wrong, I'm just saying that that report didn't sound like it was exactly condoning supplemental AA, IMO.

Did I understand you correctly that the ratio of Omega-3:Omega-6 should be closer to 1:1, or did you mean something entirely different? If you actually meant Omega-3:Omega-6, then the ratio should in fact be much higher than 1:1! Please clarify.

[luke1984]

I would like to try some of this, it's a very interesting substance.

But AA is not evil, but it does seem to make the insulin receptors less sensitive. So I'm wondering how hard gaining mass is after an AA cycle?

[rpen22]

Did I understand you correctly that the ratio of Omega-3:Omega-6 should be closer to 1:1, or did you mean something entirely different? If you actually meant Omega-3:Omega-6, then the ratio should in fact be much higher than 1:1! Please clarify.

Yes that was, indeed, a typo. Thank you. What I was meaning was that nutritionists(at least what I've been taught) say that the ratio of n-6:n-3 should be between 1:1 and 4:1, without experiencing excessive pro-inflammatory effects.

[beebab]

I would like to try some of this, it's a very interesting substance.

But AA is not evil, but it does seem to make the insulin receptors less sensitive. So I'm wondering how hard gaining mass is after an AA cycle?

bump.

[AdelV]

It may not be evil but I tried it and gained 0 results.

Same for 2 of my mates, one who came 3rd at the nationals.

Just like im on P-slin atm.. I dont get all the hype..

I think if u eat 4000calories a day, youll gain either way. Most loggers have perfect clean diets.

I might try it again now that its available in bulk and stack it with AE.

[ctrivedi]

It may not be evil but I tried it and gained 0 results.

Same for 2 of my mates, one who came 3rd at the nationals.

Just like im on P-slin atm.. I dont get all the hype..

I think if u eat 4000calories a day, youll gain either way. Most loggers have perfect clean diets.

I might try it again now that its available in bulk and stack it with AE.

Yea bro, I completely understand the disappointment when you spend your hard earned cash and see no results. I've been reading these forums and the x-factor logs - the discussions got me to try some - I'm on day 19 on x-factor -- off creatine, off NO products, off everything (including melatonin and caffeine) -- and though I've seen just slight weight gain (... still waiting), I continue to see steady strength gains (even tho I've cycled off creatine) -- and I've been lifting for 14 years, so I know when something works for me. It's the real deal (at least in my case) -- tho i gotta admit DOMS is no joke, and if someone wants to try this -- they better be willing to lift through some serious muscle soreness.

just my .02 cents

oh yeah, first post, so bless me or something hopefully I'll have more to say in the future!

[jjohn]

Yea bro, I completely understand the disappointment when you spend your hard earned cash and see no results. I've been reading these forums and the x-factor logs - the discussions got me to try some - I'm on day 19 on x-factor -- off creatine, off NO products, off everything (including melatonin and caffeine) -- and though I've seen just slight weight gain (... still waiting), I continue to see steady strength gains (even tho I've cycled off creatine) -- and I've been lifting for 14 years, so I know when something works for me. It's the real deal (at least in my case) -- tho i gotta admit DOMS is no joke, and if someone wants to try this -- they better be willing to lift through some serious muscle soreness.

just my .02 cents

oh yeah, first post, so bless me or something hopefully I'll have more to say in the future!

I bless you

[ReaperX]

What effects does AA have on the heart/cardiac muscle ?

[ReaperX]

and blood lipid levels too for that matter.

[ReaperX]

jjohn-


Any info on blood lipid levels/cardiac muscle/heart effects ?

[jjohn]

jjohn-


Any info on blood lipid levels/cardiac muscle/heart effects ?

I'll have to get back to you on that I ain't 100% sure. But I am positive it has beneficial properties on lipids and heart.

[DeerDeer]

I've read this study (if one even wants ot call it that) as well as several of the abstracts that tested for inflammatory markers. Short cycles may not be harmful (in those without any pre-existing inflammatory disorder).

I would still recommend everyone be wary given that AAcid is a precursor to MANY pro-inflammatory as well as anti-inflammatory regulators.

Take IBD or eczema for that matter - if you have it or a fam history of it - I would not recommend this product.

I'll have to get back to you on that I ain't 100% sure. But I am positive it has beneficial properties on lipids and heart.