Arachidonic Acid and Cancer
- 10-07-2007, 12:37 PM
Arachidonic Acid and Cancer
In my opinion there is not a sexier sounding supplement on the market than X-Factor. 10-15 lbs of lean gains, no hormonal side effects, what more could a guy want? But arachidonic acid is linked to prostate cancer because it converts into 12-HETE and 5-HETE.
I have two questions in realtion to this; First of all, how risky is a cycle of X-factor. It claims to be clinically safe, but that's a pretty vague statement. Are the claims of AA being dangerous overstated?
My other question is whtether the conversion of AA into 12 and 5 -HETE is integrial to the muscle gaining process of X-Factor, or if taking something like saw palmetto, which blocks conversion into 12 and 5 HETE, would help prevent the tumorous growth while still maintaining muscular gains.
I really want to give this product a go, but my family has a history of cancer, so I'm naturally cautious. Let me know if you have any info.
- 10-07-2007, 03:35 PM
10-07-2007, 03:42 PM
if you have a family history of cancer, I would say avoid x-factor. x-factor does not cause cancer but it will speed it up if you already have prostate cancer. saying x-factor causes cancer is like saying red meat and eggs will give you cancer as well. Maybe someone can chime in here with some more knowledge than me. for what it's worth, as a healthy individual, one cycle wont kill me. Although i dont have a family history of cancer however. tough call.
10-07-2007, 04:08 PM
10-07-2007, 05:36 PM
What i've seen as far as link to prostate cancer is that it increases rate of growth of cancer cells in vitro. Thats not creation of cancer, nor is it actually as measured in living humans. So I take it with a grain of salt. Also, I have so far been unable to find any reasonable numbers to use to convert the dosage of AA in those studies to human ingestion levels. So its hard to say whether for the purpose of the studies the level of AA is the equivalent to 1g a day or 100 or 1000. Similar to the old studies done on saccarin. I'm not surprised that the equivalent of 50,000 cans of diet soda a day of saccarin (metabolism + weight adjusted) would cause cancer in the rats.
10-07-2007, 05:38 PM
my father has just recently had his prostate removed, and i'm still going to do an xfactor cycle starting in 2 weeks.
10-07-2007, 05:51 PM
Okay, there has been many questions about this, and been answered many times already.
Arachidonic will NOT cause cancer, it is also stated on the bottle that it has to been consumed by HEALTHY INDIVIDUALS. Which means that you do not have a tumor already. And saw palmetto is not advised because it will hinder AA's effects. Hope this clears up the confusion.
AA is found in baby formulas to help with growth. Do you think they would add that if there is a detrimental effect on a baby?
X Factor is very sexy and will be for a long time. We stand by our products and will always do. Let me know if you have any questions!
10-07-2007, 07:16 PM
10-08-2007, 12:44 AM
FYI, everything causes cancer, everything.
You think that water you drink out of the sink tap is really all that clean ? Hello carcinogen city.
10-08-2007, 12:51 AM
10-08-2007, 02:03 AM
10-08-2007, 05:56 AM
Basically i can show you statistical evidence that swallowing your own saliva is fatal - in 100% of cases it ends in death. Might take 90 years...
10-08-2007, 07:07 AM
10-08-2007, 08:07 AM
10-08-2007, 07:31 PM
10-08-2007, 07:32 PM
10-08-2007, 07:40 PM
Easy I do sometimes buy organic but again, I think the point I was trying to make is that I try to do good things but even at that in todays world it isn't easy or cheap.So I can definitely do better but I can't be in fear of everything either.I do think that me and a lot of people on these boards do a hell of a lot better than the general public.Just watch people at work what they eat or just look at them-To quote Tipsta-"the proof is in the pudding and their physiques are Tapioca".Again I'm hardly perfect but I try. I've been doing really good for a while again now(still adjusting to a big move,etc.)and I think it should only get better.
10-08-2007, 07:47 PM
yeah, its hard too to even figure out which risks are worse than which other risks. Almost impossible to know really
I buy organic on and off, depends on the product. I dont really go out of my way, and I wont spend a 50% premium either.
06-14-2014, 04:01 PM
06-14-2014, 04:07 PM
06-14-2014, 05:27 PM
06-14-2014, 06:41 PM
06-14-2014, 09:55 PM
Hahahha, wow. I remember this thread from all those years ago.
Yeah. This is old news. We basically put the cancer issue (and every other issue) to rest. I do not exaggerate when I say that MN, William Llewellyn, and X-Factor have literally rewritten the book on fatty acids.
06-14-2014, 10:07 PM
06-14-2014, 10:56 PM
06-14-2014, 11:01 PM
http://www.ncbi.nlm.nih.gov/m/pubmed/24435810/ Date of the information was just posted may of 2014 which brings it to current status
BACKGROUND: Arachidonic acid (AA) pathway has been shown to play a role in the development and progression of prostate cancer (PCa). In this study we aimed to assess the changes in concentrations of hydroxyeicosatetraenoic acids (HETEs) in serum samples from patients diagnosed with PCa compared to controls.
METHODS: HETEs were determined using ultrahigh pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
RESULTS: Elevated concentrations of 5-HETE, 8-HETE, 11-HETE and 15-HETE were observed in 6 out of 20 patients diagnosed with PCa; no statistical differences with controls were observed for 12-HETE and AA in the discovery set. An independent validation set composed of 222 samples divided in five groups ranging from subjects with low PSA and no PCa, to patients with advanced PCa was included. In 30% of the patients in the advanced PCa group, up to ten times higher concentrations of the same set of HETEs were observed with a significant concomitant decrease of the concentration of AA. Logistic regression and Kaplan-Meier curves illustrate that a decreased concentration of AA is a predictor of PCa biochemical recurrence after radical prostatectomy (RP).
CONCLUSIONS: From the present study we conclude that a significant association between AA and AA metabolites in serum and PCa progression exists, although serum concentrations of HETEs exhibited low sensitivity toward the diagnosis of PCa.
Last edited by symbianblack; 06-14-2014 at 11:03 PM. Reason: Added date of information
06-14-2014, 11:03 PM
06-14-2014, 11:05 PM
06-14-2014, 11:10 PM
Serious Nutrition Solutions Representative
X-gels: Arachidonic Acid made affordable
06-14-2014, 11:12 PM
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