Sarm-X...hilarious or harmful?

jasonschaffin

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Supplement Facts

Serving Size: 1 tablet
Servings per Container: 60


Amount Per Serving % Daily Value
Diandrone, Trans-4-Hydroxy-3-Methoxycinnamic Acid 200g **



* Percent Daily Values are based on a 2000 calorie diet.
** Percent Daily Values not established.

INGREDIENTS: Di-Calcium Phosphate, Microcrystalline Cellulose, Hydroxymethylcellulose Phthalate, Magnesium Stearate, Silica, Titanium Dioxide, Iron Oxide
Now I know everybody here knows this product is a joke but check out the "SARM" effects that ferulic acid has. Yeah its selective to androgen receptors. IN THE PROSTATE!!! Definately no effect on muscle receptors though.
Actually on second thought maybe this isn't hilarious...they could hurt someone.

Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid) inhibits the effect of androgens on the rat prostate
Journal Cellular and Molecular Life Sciences (CMLS)
Publisher Birkhäuser Basel
ISSN 1420-682X (Print) 1420-9071 (Online)
Issue Volume 35, Number 5 / May, 1979
Category Specialia
DOI 10.1007/BF01960405
Pages 696-699
Subject Collection Biomedical and Life Sciences
SpringerLink Date Tuesday, August 02, 2005

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Specialia
Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid) inhibits the effect of androgens on the rat prostate

T. Saito1, 2, T. Nohno1, 2, H. Yoshida1, 2 and H. Yokoya1, 2
(1) Department of Pharmacology, Kawasaki Medical School, 701-01 Kurashiki, (Japan)
(2) Department of Pharmacology, Iwate Medical University School of Dentistry, 020 Morioka, (Japan)

Summary Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid, FA) antagonized the effect of exogenous androgens on the ventral prostate (VP) in castrated rats as well as the effect of endogenous androgens in intact rats. FA, however, had no effect on the seminal vesicles (SV) and levator ani muscle (LAM), nor oestrogenic effect in female rats and mice. FA did not antagonize the receptor binding of testosterone nor inhibit the conversion of testosterone into 5agr-dihydrotestosterone (DHT).
Supported in part by the project fund (grant 53-403) of Kawasaki Medical School.
The authors would like to thank the Central Laboratory, Sankyo Pharmaceutical Co., Tokyo, for supplying 19-nortestosterone-17-ferulate.
 

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