John Smeton
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Hey ,
I can benifit from your brains. I got a product that has
6 -Bromodione and as I said Im anabolic free and like to stay that way. Is 6 -Bromodione an AI? from what I understand it is. Would you consider 6 -Bromodione an anabolic or "un-natural? I am kind of hesitate about using it and could use some assistance here from more knoweldgable source(s).
Here's the write-up.. 6 -Bromodione is the same thing in ALRI's Restore. I used Nolvadex XT from Gaspari 13 months ago, that was an AI and I didnt like it at all. Any expirience with it is wlecomed.
6-Bromodione: There are two types of estrogen aromatase inhibitors and application of only one leaves the other pathway open for feminizing potential.
1) 6 alpha-Bromodione is a competitive inhibitor of aromatase enzymes. Basically this means it works by way of binding to the active binding site of the aromatase enzyme resulting in prevention of interaction with other steroids that aromatize like testosterone and the rest of our favorite male androgens. This is great for rapid binding and short term aromatase control, but unfortunately a competitive inhibitor will eventually let go of the enzyme and allow it to do feminizing things to manly hormones. So, only half of the job is done, but it has its important role as well.
2) 6 beta-Bromodione is a mechanism-based irreversible inhibitor of the aromatase enzyme. An irreversible aromatase inhibitor is also referred to as a suicide inhibitor. It’s pretty cool in that it acts similar to a competitive inhibitor in the way it binds, but like a pissed-off ex-girlfriend, it is both highly selective and it will not let go until death do they part.
Together the two analogs in 6-Bromodione make sure that estrogen is under control, and many would assume that less estrogen means the prolactin would be under control as well. Often, once prolactin increases are stimulated, shutting it back down takes some extra effort and a protracted period of time. How long are you willing to wait to be an optimized male?
I can benifit from your brains. I got a product that has
6 -Bromodione and as I said Im anabolic free and like to stay that way. Is 6 -Bromodione an AI? from what I understand it is. Would you consider 6 -Bromodione an anabolic or "un-natural? I am kind of hesitate about using it and could use some assistance here from more knoweldgable source(s).
Here's the write-up.. 6 -Bromodione is the same thing in ALRI's Restore. I used Nolvadex XT from Gaspari 13 months ago, that was an AI and I didnt like it at all. Any expirience with it is wlecomed.
6-Bromodione: There are two types of estrogen aromatase inhibitors and application of only one leaves the other pathway open for feminizing potential.
1) 6 alpha-Bromodione is a competitive inhibitor of aromatase enzymes. Basically this means it works by way of binding to the active binding site of the aromatase enzyme resulting in prevention of interaction with other steroids that aromatize like testosterone and the rest of our favorite male androgens. This is great for rapid binding and short term aromatase control, but unfortunately a competitive inhibitor will eventually let go of the enzyme and allow it to do feminizing things to manly hormones. So, only half of the job is done, but it has its important role as well.
2) 6 beta-Bromodione is a mechanism-based irreversible inhibitor of the aromatase enzyme. An irreversible aromatase inhibitor is also referred to as a suicide inhibitor. It’s pretty cool in that it acts similar to a competitive inhibitor in the way it binds, but like a pissed-off ex-girlfriend, it is both highly selective and it will not let go until death do they part.
Together the two analogs in 6-Bromodione make sure that estrogen is under control, and many would assume that less estrogen means the prolactin would be under control as well. Often, once prolactin increases are stimulated, shutting it back down takes some extra effort and a protracted period of time. How long are you willing to wait to be an optimized male?
