Phenibut tolerance and reset-ad
- 06-19-2007, 08:04 PM
- 06-19-2007, 11:23 PM
at first i would say no, i do not think reset ad would have much benefit for this as this is not really a stimulating substance.
but when i think about it, and i am not positive of the action of phenibut. although it does seem phenibut would cause a spike in dopamine leaves based on the ability to build such a tolerance and feeling is similar to products the surge dopamine. what i am gettin at is if it does cause an increase in dope, well dope is a precursor to norepinephrine and epinephrine. thus, with high useage, could drain the adrenal's.
- 06-19-2007, 11:26 PM
actually, your best bet might be to take a break from phen. then when u start back up, cycle 2 weeks on, 2 off...
06-20-2007, 05:03 AM
Thanks for the info. I've been using about 2 grams twice a week for about 8 months spaced apart on a monday and thursday. It still works well but it would be nice to get the same effects as when I first started it. I've ordered a bottle of reset so if it doesnt work i'll just have to give it a break for a while.
06-20-2007, 11:08 AM
And let us know if you have ANY questions about the product or any other PAL products. You can also hop over to the PAL subforum.
06-20-2007, 11:15 AM
06-20-2007, 11:16 AM
Ok here is the deal on this.. obviously your body can build a tolerence to Phenibut. From what I can tell this tolerence is built by your a1 receptors being upregulated from over abuse..ie this is very similiar to what happens with over consumption of stimulants like Caffiene... in neonatal rats Pregnenolone has been shown to help downregulate A1 receptors... So in theory Reset-ad should help downregulate your tolerence to Phenibut. That being said I would still suggest cycling off of it for atleast two weeks.
There is a real good study about this upregulation of a1 and a2 receptors and preg's ability to help down regulate them done by the Department of Neuropsychiatry, Kagoshima University Faculty of Medicine, Kagoshima, Japan.
edit: if you need more info let me know....
06-20-2007, 08:43 PM
I've seen a few people recommeding piracetam w/ the phenibut. I've noticed no tolerance when I combine the two, but I only use it (phenibut) once a week tops.
06-21-2007, 01:39 AM
08-01-2007, 04:10 PM
08-07-2007, 11:22 AM
08-07-2007, 01:20 PM
Note to Mods: Please open up a Nootropics forum
08-07-2007, 02:02 PM
11-19-2007, 04:57 AM
hahah im so glad this topic is up here because i was wondering the same thing myself...
ive been using reset ad for the past couple of weeks and i LOVE the results i am getting..i feel like a new person.
I also had some phenibut laying around so i was wondering if i would react differently to phenibut with reset ad...
i just took 1g of phenibut so ill let u know how it turns out
11-19-2007, 10:14 AM
08-12-2009, 10:56 PM
I used Phenibut for a few days at 2 grams and it was great the first two days but then tolerance developed. Do you know whether there is a limit to tolerance, meaning beyond a certain point the effects will remain and not have tolerance (even if that means having to take many grams)?
08-16-2009, 06:35 PM
Ease off Phenibut gradually - forget the Reset. You could start using GABA, Picamilon, threanine to ease the anxiety.
Oh... dang. Its an old thread from over 2 years ago. Information irrelevant.
To the poster above Phenibut is a very powerful nootropic agent and should be used occassionally. Don't try using on any sort of regular basis unless you want to keep taking it.
Phenibut is massively powerful stuff - all with synthetic B1 (sulbutiamine) its the strongest nootropic agent I know.
10-07-2009, 02:36 PM
taking piracetam (up regulate gaba receptors? as i hvae read that it lowers alcohol tolerance) and taking pregnenolone good amount (as PAL has written it antagonizes GABA) might be a good idea to combat phen tolerance,,,who wants to try it?
well some already say piracetam can reduce tolearance so that proves it
ive taken 60mg pregnenolone 3 times a day spread apart and took GABA and i had a huge flushig effect more noticeable than the night before when i wasnt taking prg.
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