New Idea for increase Bioavailability.
- 05-12-2007, 11:51 PM
New Idea for increase Bioavailability.
Incredibly novel and possibly silly idea.
There are many great compounds out there that we as humans simply do not use, because of the absolutely terrible bioavailability.
The studies show amazing, out-of-this-world benefits using lets say 50mg of an injected supplement.
We see these studies, run to the nearest store and take 50mg of this same supplement orally, then wait... nothing happens. Why? Because of the 50mg we took of whatever the supplement is at the time, only 0.25mg made it pass the liver.
Here comes the novel idea.
If the liver is preoccupied with dealing with alcohol, is it possible that we could get more active supplement by it?
- 05-13-2007, 08:59 AM
Clarify: Serious question?Applied Nutriceuticals Representative
Better Results Through Science
Success occurs when everything you have is APPLIED.
Have you heard about N.O. Uptake? ;-)
- 05-13-2007, 09:23 AM
Well, yeah. Silly, but serious.
I was reading some theories on the French Parodox on various boards, and some people came up with the theory that~
Although Resveratrol has something like 0% Bioavailability in humans, wine drinkers somehow get a lot of the benefits of it (Resveratrol).
One of the answers I saw a few posters come up with was that...
Resveratrol got by the liver in wine drinkers to administer its amazing effects, because the liver was preoccupied dealing with the alcohol content of the wine.
05-14-2007, 07:50 AM
05-14-2007, 08:50 AM
05-14-2007, 11:08 PM
05-14-2007, 11:25 PM
05-15-2007, 03:20 AM
transdermals or injections of everything!
grapefruit juice helps with bioavailablity of orals.
05-15-2007, 09:01 PM
You've given me absolutely nothing thought-provoking or convincing, except an "I don't think that will work" answer.
How do we know alcohol doesn't disrupt the normal routines of the brain and organs, for reduced functioning?
Also, using alcohol to skew the efficiency screening of the Liver, and adding a methyl group to a steroid, are nowhere near the realm, of the same thing.
First off, "adding" a methyl group, completely changes the compound to a different one, with completely different effects.
Alcohol wouldn't change the effect of the compound to a different one, it would remain in the intended state, but hopefully with increased bioavailability.
05-15-2007, 11:22 PM
05-15-2007, 11:31 PM
05-15-2007, 11:54 PM
05-16-2007, 12:05 AM
05-16-2007, 12:16 AM
05-16-2007, 09:38 PM
Ive heard of people making orals into transdermals in the transdermal section, but im not sure.
05-29-2009, 08:51 PM
05-29-2009, 09:26 PM
the thing is in occational drinkers we only use the ADH pathway which is why more damage occurs to binge drinkers as oppoesed to alcoholics (brain vs liver respectivly)
05-29-2009, 09:28 PM
05-29-2009, 09:34 PM
sounds like a great way to fu*k yourself over and possibly stress damage your liver at the same time...
05-29-2009, 11:44 PM
Just buy "Sustain alpha" [non-prohormone thread]. Its transdermal that solves most of the problem.
Transdermal->all over the body.
05-31-2009, 04:13 AM
05-31-2009, 04:26 AM
05-31-2009, 07:52 AM
While this is a weird idea.. I've always thought that certain supps should be sublingual.. such as NO products: The sublingual route is shunted directly to your veins and your heart: leading to faster substance effects in your arteries and veins- a sublingual NO product should be fast acting and more effective!
05-31-2009, 09:01 AM
05-31-2009, 01:53 PM
Increasing bioavailability of a substance by decreasing the effeciency of your liver via bombardment with alcohol is asinine.
06-01-2009, 03:11 AM
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