*THE Beta-Alanine, Carnosine Thread, Brought to you by ATHLETIC EDGE NUTRITION*

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  1. Quote Originally Posted by Rhyalus View Post
    Did this text come from MD magazine or vice versa?

    Also, can beta alanine be useful without sugar to help shuttle the stuff into the cells?

    Regards,
    R
    Yes, I wrote it originally for MD. When the current issue of MD is off the newsstands, I will post the full article in MD's format. In the mean time, I figured it would be beneficial to post excerpts on the forums, for anyone who hasn't had a chance to read the full article.

    Oh yes, Beta-Alanine regardless of carbs will get into your cells and boost carnosine concentrations significantly. Carbs simply speed up the process.


  2. Who can benefit from Beta-Alanine?

    1 Individuals participating in weight training looking to gain lean muscle mass and increase strength.
    2 Any individual involved in athletic activities where strength, power and muscular endurance are needed.
    3 Active individuals who have reached a training plateau and are looking for a supplement to take them to the next level
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  3. Is there any info around how beta-alanine carnosine effects workout body temperature, it may be the Steeledge but i have been super warm and sweating like crazy, ideal for hard injury free workouts.

  4. Quote Originally Posted by somewhatgifted View Post
    Is there any info around how beta-alanine carnosine effects workout body temperature, it may be the Steeledge but i have been super warm and sweating like crazy, ideal for hard injury free workouts.
    That has been reported by most of our IntraXCell testers. If I remember correctly, there is no research to support a rise in body temp.......but I will check.

  5. Quote Originally Posted by somewhatgifted View Post
    Is there any info around how beta-alanine carnosine effects workout body temperature, it may be the Steeledge but i have been super warm and sweating like crazy, ideal for hard injury free workouts.
    That's a very good question and one I don't have the answer for as of yet. I know every time I take IXL I sweat more, I just don't know why specifically. I've been meaning to look further into it, I'll see what I can dig up.

    At last years ISSN conference I asked that EXACT question to none other than the pioneer of Beta-Alanine performance research, Dr.Harris. He told me they weren't seeing increases in temperature. There is something going on though in regards to sweating and I will see what I can come up with.

    BTW, I thought of you today, regarding a new project we have in the works.
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  6. So this must mean Athletic Edge has a Beta Alanine supp coming out?

  7. Quote Originally Posted by CryingEmo View Post
    So this must mean Athletic Edge has a Beta Alanine supp coming out?
    Yeah dude its here now at the planet called IntraXcell

    IntraXcell (180 caps) By Athletic Edge

    Supplement Facts
    Serving Size: 3 capsules
    Servings per Container: 60

    Amount Per Serving % Daily Value
    Vitamin E (as d-alpha tocopherol Acetate) 15 IU
    50%
    2XCell Blendô:
    -(Beta-Alanine (2g), N-Acetyl L-Cysteine, Alpha-Lipoic Acid) 2,201mg **


    * Percent Daily Values are based on a 2000 calorie diet.
    ** Percent Daily Values not established.

    INGREDIENTS: Gelatin, cellulose, silicon dioxide, magnesium stearate, titanium dioxide, FD&C blue #2.

  8. Would that be comparable to Incarnate?

  9. Quote Originally Posted by CryingEmo View Post
    So this must mean Athletic Edge has a Beta Alanine supp coming out?

    No, we have had our Beta-Alanine supplement IntraXCell out for over a year now. We have many IntraXCell/Beta-Alanine threads on many forums, but we thought we would do something different with this one. This thread is specific to the science of Beta-Alanine and separate from our product. It's intended for people to have a place to go and learn about Beta-Alanine.

  10. Quote Originally Posted by Athletic Edge N View Post
    No, we have had our Beta-Alanine supplement IntraXCell out for over a year now. We have many IntraXCell/Beta-Alanine threads on many forums, but we thought we would do something different with this one. This thread is specific to the science of Beta-Alanine and separate from our product. It's intended for people to have a place to go and learn about Beta-Alanine.
    Oh my bad bro. I'm trying to keep up with all the supps!

  11. Quote Originally Posted by CryingEmo View Post
    Oh my bad bro. I'm trying to keep up with all the supps!
    LOL, I hear you, it can get pretty overwhelming at times.

    IntraXCell was the first capsule Beta-Alanine product in the world.
    It was actually the first dedicated Beta-Alanine product out there,that didn't use a handful of other ingredients along with the Beta-Alanine, such CM or creatine.


    BTW, if you have a chance, check out our five page Beta-Alanine article in this months issue of Muscular Development.

  12. How long will it take to start noticing benefits?


    Performance benefits typically occur in as little as two weeks, although some individuals will notice benefits within one week. As carnosine levels increase, the benefits will follow. The most dramatic results are generally experienced within the 3-4 week range but they donít stop there. Recent research is now showing carnosine levels continue to increase for a minimum of 12 weeks which is why we recommend staying on Beta-Alanine for at least three months to optimize your carnosine levels.

    Immediate benefits: Many users experience intense vasodilation/pumps from the very first dose of Beta-Alanine. This experience occurs because Beta-Alanine increases carnosine and carnosine is a powerful precursor in generating nitric oxide synthase (a group of enzymes necessary for making the powerful vasodilator nitric oxide).

  13. Quote Originally Posted by CryingEmo View Post
    Would that be comparable to Incarnate?
    Nothing compares to IntraXcell it is the best BA capped product on the market.
    Diet and Nutrition Advisor

  14. Quote Originally Posted by Mickfootie View Post
    Nothing compares to IntraXcell it is the best BA capped product on the market.
    :bruce2:

  15. Quote Originally Posted by Athletic Edge N View Post
    How long will it take to start noticing benefits?


    Performance benefits typically occur in as little as two weeks, although some individuals will notice benefits within one week. As carnosine levels increase, the benefits will follow. The most dramatic results are generally experienced within the 3-4 week range but they don’t stop there. Recent research is now showing carnosine levels continue to increase for a minimum of 12 weeks which is why we recommend staying on Beta-Alanine for at least three months to optimize your carnosine levels.

    Immediate benefits: Many users experience intense vasodilation/pumps from the very first dose of Beta-Alanine. This experience occurs because Beta-Alanine increases carnosine and carnosine is a powerful precursor in generating nitric oxide synthase (a group of enzymes necessary for making the powerful vasodilator nitric oxide).
    I almost accussed BA of being a contributor to my high BP, until I read vasodilation. I looked it up, nitric oxide is my friend. I'm going to buy a case of this stuff.

    Spiraling high blood pressure linked to nitric oxide deficiency

  16. Quote Originally Posted by Mach .78 View Post
    I almost accussed BA of being a contributor to my high BP, until I read vasodilation. I looked it up, nitric oxide is my friend. I'm going to buy a case of this stuff.

    Spiraling high blood pressure linked to nitric oxide deficiency

    Much like creatine, there are MANY legit health/medical applications for Beta-Alanine that go far and beyond exercise performance.

    It's one of the best ingredients you could take for general health, regardless of the exercise performance benefits. We focus on the exercise performance benefits, as that alone is a huge topic that still isn't well understood by many and is most relevant to the the forum crowds we interact with. Other topics on beta-alanine and carnosine that are particularly impressive are on neuroprotection, neurodegenerative diseses, autism..ect.ect

  17. Are there any methods that may increase beta-alanine’s ability to increase carnosine levels?

    Yes. A recent study showed that a group of subjects taking Beta-Alanine with carbohydrates increased performance gains in half the time of the group taking an equal amount of beta-alanine without carbohydrates. Carbohydrates spike insulin and one of insulin’s effects is to increase amino acid (such as beta-alanine) transport into our cells.
    While not research supported as of yet, taking Beta-Alanine pre-workout and post-workout may increase the uptake of Beta-Alanine into our muscles. Amino acid nutrient timing studies have clearly shown, when amino acids are ingested Pre-Workout and Post-Workout, their rate of uptake into our muscle is increased. The improved uptake is largely due to increased blood flow during exercise.

  18. What is the prickling I feel when I first take Beta-Alanine?

    The prickling - called parathesia - is caused by beta-alanine binding to nerve receptors, activating them and causing them to discharge/fire. Many of these nerves are below the skin, giving a prickling/pins-and-needles sensation. This sensation begins approximately 15-20 minutes after ingesting beta-alanine and usually continues for 1-1.5 hours. The intensity varies depending on dosing, individual sensitivity and potentially from activators of Ca2+ channels, such as caffeine. This sensation, though generally enjoyed, often subsides over a few weeks of continued use. Carbohydrates/food may also blunt the prickling effect from beta-alanine.

  19. If I donít feel the prickling does that mean beta alanine isnít working on me?


    The prickling sensation does not occur at all in some individuals, even when taking 4-6 grams of beta-alanine at one time. Do not worry if you are in this group. The prickling is NOT a sign that beta-alanine is working or being absorbed by your muscles and converted to carnosine. If you are feeling nothing, you need not be concerned as it is still increasing your carnosine stores as research has repeatedly shown.

    A good example of this phenomenon is when combining carbohydrates with beta-alanine. Not only do carbohydrates blunt much of the prickling sensations, they also increase beta-alanine's performance gains faster than beta-alanine without carbohydrates.

    Another good example is comparing studies that measure carnosine concentrations using multiple small 800 mg doses of beta-alanine vs. studies using multiple doses of 1.6 g of beta-alanine. The total daily amount of beta-alanine ingested is similar and the duration of the studies using both dosage strategies is matched up as well. 800 mg is low enough to cause little to no prickling, based off feedback from both research and anecdotal, where as 1.6 g can cause quite a lot. The outcome of both studies showed carnosine concentrations were very similar.


    We have an exciting announcement on Monday.

  20. Quote Originally Posted by Athletic Edge N View Post
    LOL, I hear you, it can get pretty overwhelming at times.

    IntraXCell was the first capsule Beta-Alanine product in the world.
    It was actually the first dedicated Beta-Alanine product out there,that didn't use a handful of other ingredients along with the Beta-Alanine, such CM or creatine.


    BTW, if you have a chance, check out our five page Beta-Alanine article in this months issue of Muscular Development.
    I just read this article last night in MD now i come on here and see this..............it must be love.

  21. Quote Originally Posted by Australian made View Post
    I just read this article last night in MD now i come on here and see this..............it must be love.
    What did you think of it?

  22. Good article, very informative. I'll most likely give your product a try in the next month or two when i finish using my current stash of creatyine.

    I'm in London by the way.

  23. Is taking taurine at the same time as beta-alanine going to stop beta-alanine from boosting carnosine and performance levels?

    While there is certainly potential for problems when taking these two together (they share the same transporter into tissues), it hasnít yet been supported in the research to any level of significance. In fact, a recent study by Dr. Harris, showed that the increase in muscle carnosine with beta-alanine was NOT reduced when taurine was taken along with it. Also, everyone bare in mind, CARN is concentrated much higher in Type 2 muscle fibers, while taurine is in much higher concentrations in Type 1. further limiting their competition issues related to muscle performance.


    We could get into the biochemistry of why taking taurine with beta-alanine may not seem like a good idea but we have a more simple and conclusive explanation just in case you wanted more proof to support Dr. Harrisís study. Since there is a group of studies that used either beta-alanine by itself or beta-alanine with taurine, we examined them to determine if there were any differences in the resulting carnosine concentrations. While more research is always needed, there are quite a few beta-alanine vs. beta-alanine plus taurine studies, and their outcomes are all the same. There is little to no difference in carnosine concentrations. In other words, taurine does not inhibit beta-alanine from being absorbed to any level of significance, otherwise carnosine levels would have been lower in the beta-alanine plus taurine studies.


    That concludes our summary, please feel free to jump in with any questions. We will continuously update this thread as more research and information comes out on Beta-Alanine

  24. Exclamation


    Rationale for taking beta-alanine pre&postWO timing.


    While, we have explained within this thread and others, why we suggest to take advantage of the pre&postWO windows on training days whenever possible. Here is a more detailed explanation from a post of mine in a recent thread, as many are giving advice that there is no reason/benefit in taking beta-alanine, pre&postWO. They are wrong.


    We do not suggest pre&postWO beta-alanine ingestion for acute performance benefits, but for the purpose of increased delivery and increased intramuscular uptake. That's not to say, there aren't possible acute benefits from pre&postWO timing of BA, but at this time there is no support one way or the other. There is however amino acid pre&postWO nutrient timing studies, that can be used as support for the rationale of suggesting BA taken pre&postWO.

    The reasoning on why we have always suggested taking BA, Pre&PostWO, is actually very simple and it should make sense to anyone familiar with nutrient timing amino acid or creatine studies. In a nutshell, our body's greatly increase the delivery and uptake of amino acids/creatine ect, when taken Pre/PostWO, largely due to exercise induced increased blood flow . Beta-Alanine is an amino acid and its rate of uptake is HIGHLY likely to be increased when taken pre/postWO. We will likely also see some other benefits when taking BA pre/post, but that's for another time.

    You don't have to take beta-alanine, pre/postWO(especially if you find the prickling bothersome during your workout) and the most important thing is to take it everyday, regardless of timing. But when ever possible, we will always suggest, you take advantage of the pre&postWO windows of opportunity for increased BA uptake and reap the benefits from BA as fast as possible.

    We have also, always recommended BA be taken with carbs when ever possible for both uptake reasons as well as blunting the prickling sensation if you find it bothersome. The reason is, a beta-alanine study, comparing beta-alanine to beta-alanine+carbs, showed the group using Beta-alanine+carbs, had equivalent performance gains in HALF the time as the beta-alanine only group in the first month. This quite significant, especially for someone looking to get the benefits from beta-alanine as fast as possible.


    Neither of these recommendations are musts, but taking advantage of the combination, should greatly increase BA uptake and bring on the performance benefits much faster, especially in the first month.


    None of us, have to take advantage of nutrient timing science, be it with creatine,beta-alanine, protein/carb shakes ect. But if you are looking to maximize most of your supplements absorption and get the positive effects as fast as possible, I can't see any reason why you wouldn't want to take advantage of these windows of opportunity.
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