Sesamin decreases exercise-induced lipid peroxidation?

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    Sesamin decreases exercise-induced lipid peroxidation?


    Hi there, I was reading through pubmed to help me to decide wheter to buy more sesamin or not when I encountered this strange article:

    Quote Originally Posted by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retri eve&dopt=AbstractPlus&list_uid s=12968212&query_hl=24&itool=p ubmed_DocSum
    1: Int J Sports Med. 2003 Oct;24(7):530-4.Click here to read Links
    Protective effect of sesamin administration on exercise-induced lipid peroxidation.

    * Ikeda T,
    * Nishijima Y,
    * Shibata H,
    * Kiso Y,
    * Ohnuki K,
    * Fushiki T,
    * Moritani T.

    Laboratory of Applied Physiology, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan.

    To investigate the mechanism of antioxidative effects of sesamin in vivo, 32 male ddY mice were administered with 10 mg/kg or 100 mg/kg of sesamin (S10, S100), 100 mg/kg of vitamin E (VE100) or control sample (C). They were subjected to 30 min of swimming exercise 2 h after the sample administration by using a new forced-swimming apparatus, i. e. an adjustable-current swimming pool. Exercise resulted in a significant increase in plasma lipid peroxides (LPO) in C and VE100 (p < 0.01), but not in S10 and S100. S100 showed significantly higher total glutathione peroxidase activity and glutathione S-transferase activity in liver compared to C (p < 0.05). In conclusion, sesamin may enhance LPO degradation in the liver resulting in the strong protective effects against exercise-induced plasma lipid peroxidation.

    PMID: 12968212 [PubMed - indexed for MEDLINE]
    Am I reading this correctly in saying that sesamin will shut-down fat-burning post-exercise?

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    Dr. Gonzo's Avatar
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    You're confusing a few terms here.

    Lipid Peroxidation is free radical induced electron theft resulting in cellular damage.

    Fatty acid oxidation is the burning off of fat in the mitochondria as a fuel source.
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    Oh ok, thanks for clearing that up
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    Is that you, Marc??

    I thought you abandoned that username.
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    If you are referring to me, then no, I am not Marc.

    Your friend must be a classy guy though
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    Quote Originally Posted by Sir Savage View Post
    Is that you, Marc??

    I thought you abandoned that username.
    I registered here with it a few years ago, as well as a few other places...I just changed it to my real name at Mind and Muscle for the Guru Panel purposes.
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