R-ALA vs. ALA revisited - AnabolicMinds.com

R-ALA vs. ALA revisited

  1. Skye's Avatar
    Join Date
    Apr 2003
    Posts
    1,944
    Rep Power
    1112

    Reputation

    R-ALA vs. ALA revisited


    Everyone knows that ALA is a chiral molecule. And that the R version is supposed to be far better. What is not always clear is whether the greater cost for the R-ALA is worth it. Lots of opinions and tons of studies on this old topic so I wanted to see what the general consensus was now and want your opinions was on my particular situation.

    Being diabetic I take ALA regularly, recently I tried 300mg 4 times a day. Worked well but it has become a pain in the ass with my new schedule. So I was looking at trying 600mg twice a day. Then I thought about taking a look at R-ALA again. The price has come down and it is supposed to work better, anywhere from 2 to 12 times with a somewhat general consensus of about 3 times as effective as the ALA. So that comes to 200mg twice a day to maintain the same effectiveness as the ALA, supposedly.

    Here are the price breaks; I can get ALA 600mg capsules for 22 cents a gram. That would be 66 cents in “R-ALA terms”. R-ALA 200mg capsules can be had for $1.44 a gram. That is 2.18 times as much as the ALA for the same effective dose.

    As for the cost it really isn’t a big issue, I will spend money for a better product provided that there is a clear benefit to doing so. But on the other hand I am a cheap bastard by nature and hate to waste money regardless of circumstances. (I have driven across town to buy shallots just because I wasn’t going to pay the equivalence of 7 dollars a pound vs. 3 even for a half pound.)

    So the question here is there a clear benefit to using R-ALA that justifies the cost?

  2. Rodja's Avatar
    Stats
    5'10"  220 lbs.
    Join Date
    Jan 2006
    Age
    30
    Posts
    23,015
    Rep Power
    917973

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    I know they are slightly different, but I have had great results with KR-ALA as opposed to just ALA. I tried ALA at 1200mg/day and did not see the results I got from 600mg of KR-ALA.
  3. jjohn's Avatar
    Join Date
    Jun 2006
    Age
    26
    Posts
    6,538
    Rep Power
    77389

    Reputation Reputation

    Yeah, r-ala is supposed to be a lot more effective. I have tried ALA and really saw veins popping. I saw stick with what works. Glucophase did not do much for me, so I guess I would go for the least expensive first, and see...
    •   
       

  4. theshocker21's Avatar
    Join Date
    Jan 2006
    Age
    30
    Posts
    379
    Rep Power
    296

    Reputation

    Its worth it. Have you checked prices on R-ALA by Primaforce?
  5. Skye's Avatar
    Join Date
    Apr 2003
    Posts
    1,944
    Rep Power
    1112

    Reputation

    thanks for the replies, I think I am going to try the KR-ALA as I have a lot of pos responses.
  6. jmh80's Avatar
    Stats
    5'10"  180 lbs.
    Join Date
    Mar 2004
    Age
    34
    Posts
    8,110
    Rep Power
    9661

    Reputation

    Skye - try the Na-R-ALA.
    Custom has it.

    I love it's solubility. That was my major beef with K-R-ALA.

    I don't think ALA is "one for one" on a milligram basis with R-ALA.
  7. machinehead's Avatar
    Join Date
    Apr 2005
    Age
    35
    Posts
    606
    Rep Power
    418

    Reputation

    The S isomer of ALA actually cancels the benefits of the R isomer so you are much better of with R-ALA [or K-R-ALA or Na-R-ALA]. At least that's what Poliquin claims.
  8. Skye's Avatar
    Join Date
    Apr 2003
    Posts
    1,944
    Rep Power
    1112

    Reputation

    Thanks
  9. Robboe's Avatar
    Join Date
    Mar 2005
    Posts
    4,927
    Rep Power
    8379

    Reputation

    Seems like a done topic, but just fyi really, the S(-) enantiomer doesn't exist in nature. It is a byproduct of the chemical synthesis for the R(+) enantiomer, leading to racemic ALA (a 50:50 blend of each). A lot of the older research into r-ALA smply referred to the compound as "ALA" because at the time they were not aware of the synthetic byproduct.

    Why the S(-) does seem to give stability to the R(+) in this state, there does appear to be some antagonising effects between the two, so the r-ALA route is best to go in my opinion, preferably bonded to a stabilising element (the sodium-RALA looks good but my only experience in this regard is with the potassium-RALA in glucophase xr).
    The Driven Blog
    Follow DS on Facebook and Twitter!

    Craze™ is NOW AVAILABLE!
  10. jmh80's Avatar
    Stats
    5'10"  180 lbs.
    Join Date
    Mar 2004
    Age
    34
    Posts
    8,110
    Rep Power
    9661

    Reputation

    El Roberto,
    Y'all gonna reformulate with Na-R-ALA???
  11. Robboe's Avatar
    Join Date
    Mar 2005
    Posts
    4,927
    Rep Power
    8379

    Reputation

    Dunno. I'm not entirely convinced it'd be worth it. Stellar results are had with KR-ALA.

    The Na-RALA just seems like it yields more R-ALA but costs a little more (probably balancing out in the end). I'm not sold on it being anymore than that.
    The Driven Blog
    Follow DS on Facebook and Twitter!

    Craze™ is NOW AVAILABLE!
  

  
 

Similar Forum Threads

  1. r-ala vs. yellow gold
    By sanchezgreg18 in forum Supplements
    Replies: 0
    Last Post: 06-03-2009, 01:19 PM
  2. ALA vs. ALCAR
    By lawnboy246 in forum Supplements
    Replies: 6
    Last Post: 01-02-2007, 10:52 AM
  3. ALA vs R-ALA
    By Eunisx in forum Supplements
    Replies: 3
    Last Post: 10-30-2006, 09:04 AM
  4. K-R-ALA vs. GXR?
    By houseman in forum Supplements
    Replies: 2
    Last Post: 07-14-2005, 11:18 PM
  5. ala vs r-ala
    By Super Tri's in forum Supplements
    Replies: 2
    Last Post: 03-10-2003, 10:54 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in