ArnoldIsMyIdol
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Flaxseed supplementation in hyperlipidemic patients.
Mandasescu S, Mocanu V, Dascalita AM, Haliga R, Nestian I, Stitt PA, Luca V.
Roman City Hospital, Endocrinology/Diabetes Service, Gr.T. Popa University of Medicine and Pharmacy Iasi, School of Medicine.
The aim of this study was to investigate the effect of daily consumption of dietary flaxseed (as a source of linolenic acid, LNA) on plasma lipid concentrations in mildly hyperlipidemic patients. METHODS: 40 hyperlipidemic patients with plasma total cholesterol greater than 240 mg/dL were distributed in 3 groups: 10 patients who received hypolipidic diet (diet group), 10 patients who received hypolipidic diet plus statins (diet+HL group), 20 patients who received hypolipidic diet plus 20 g ground flaxseeds/day (diet+flax group). Body mass index (BMI), serum total cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), triglycerides (TG) and cholesterol/HDL-cholesterol ratio were measured at the beginning and after 60 days of treatment. RESULTS: Flaxseed supplementation was associated with significant reductions in TC (-17.2%), LDL-C (-3.9%), TG (-36.3%) and TC/HDL-C ratio (-33.5%). There were no significant differences in absolute change in BMI nor in percentaged change in TC, HDL-C, LDL-C, TC/HDL-C ratio between flaxseed and statin groups. CONCLUSIONS: Dietary flaxseed significantly improves lipid profile in hyperlipidemic patients and may favorably modify cardiovascular risk factors.
Mandasescu S, Mocanu V, Dascalita AM, Haliga R, Nestian I, Stitt PA, Luca V.
Roman City Hospital, Endocrinology/Diabetes Service, Gr.T. Popa University of Medicine and Pharmacy Iasi, School of Medicine.
The aim of this study was to investigate the effect of daily consumption of dietary flaxseed (as a source of linolenic acid, LNA) on plasma lipid concentrations in mildly hyperlipidemic patients. METHODS: 40 hyperlipidemic patients with plasma total cholesterol greater than 240 mg/dL were distributed in 3 groups: 10 patients who received hypolipidic diet (diet group), 10 patients who received hypolipidic diet plus statins (diet+HL group), 20 patients who received hypolipidic diet plus 20 g ground flaxseeds/day (diet+flax group). Body mass index (BMI), serum total cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), triglycerides (TG) and cholesterol/HDL-cholesterol ratio were measured at the beginning and after 60 days of treatment. RESULTS: Flaxseed supplementation was associated with significant reductions in TC (-17.2%), LDL-C (-3.9%), TG (-36.3%) and TC/HDL-C ratio (-33.5%). There were no significant differences in absolute change in BMI nor in percentaged change in TC, HDL-C, LDL-C, TC/HDL-C ratio between flaxseed and statin groups. CONCLUSIONS: Dietary flaxseed significantly improves lipid profile in hyperlipidemic patients and may favorably modify cardiovascular risk factors.
