ALCAR Vs. PLCAR....Whats better? Benefits?

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    ALCAR Vs. PLCAR....Whats better? Benefits?


    been reading on these 2 supps.....but.....i want to know what you guys feel as the benefits of this stuff...and the difference between the 2.......do they both have mental bonuses...ive heard alcar is better mentally than plcar....but some people say that plcar is all around better than alcar....also.....fat loss benefits?? some say yes....some dont mention it.....let me know what you guys think

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    damn..no one has tried either of these products?
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    I have tried ALCAR, but never PLCAR. I havn't seen many reviews on PLCAR, all I know is Primaforce's Durablast has it in it. Thats the only supplement besides buying it in bulk, that I have seen. I tried to get some PLCAR but it was sold out when I tried to get it. Otherwise I would be able to chime in on the differences.
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    I use Alcar when I feel like doggy doo-doo, I take it with R-ala. Never heard of the other one. Alcar is nice for sure, but I wouldnt want to take it everyday. Its a great pick me up when your not feeling good or overly tired.
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    Originally Posted by Propionyl-L-carnitine and acetyl-L-carnitine in chronic fatigue syndrome
    OBJECTIVES: We compared the effects of acetylcarnitine, propionylcarnitine and both compounds on the symptoms of chronic fatigue syndrome (CFS).
    METHODS: In an open, randomized fashion we compared 2 g/d acetyl-L-carnitine, 2 g/d propionyl-L-carnitine, and its combination in 3 groups of 30 CFS patients during 24 weeks. Effects were rated by clinical global impression of change. Secondary endpoints were the Multidimensional Fatigue Inventory, McGill Pain Questionnaire, and the Stroop attention concentration test. Scores were assessed 8 weeks before treatment; at randomization; after 8, 16, and 24 weeks of treatment; and 2 weeks later.
    RESULTS: Clinical global impression of change after treatment showed considerable improvement in 59% of the patients in the acetylcarnitine group and 63% in the propionylcarnitine group, but less in the acetylcarnitine plus propionylcarnitine group (37%). Acetylcarnitine significantly improved mental fatigue (p =.015) and propionylcarnitine improved general fatigue (p =.004). Attention concentration improved in all groups, whereas pain complaints did not decrease in any group. Two weeks after treatment, worsening of fatigue was experienced by 52%, 50%, and 37% in the acetylcarnitine, propionylcarnitine, and combined group, respectively. In the acetylcarnitine group, but not in the other groups, the changes in plasma carnitine levels correlated with clinical improvement.
    CONCLUSIONS: Acetylcarnitine and propionylcarnitine showed beneficial effect on fatigue and attention concentration. Less improvement was found by the combined treatment. Acetylcarnitine had main effect on mental fatigue and propionylcarnitine on general fatigue.
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    Quote Originally Posted by 1HP
    Originally Posted by Propionyl-L-carnitine and acetyl-L-carnitine in chronic fatigue syndrome
    OBJECTIVES: We compared the effects of acetylcarnitine, propionylcarnitine and both compounds on the symptoms of chronic fatigue syndrome (CFS).
    METHODS: In an open, randomized fashion we compared 2 g/d acetyl-L-carnitine, 2 g/d propionyl-L-carnitine, and its combination in 3 groups of 30 CFS patients during 24 weeks. Effects were rated by clinical global impression of change. Secondary endpoints were the Multidimensional Fatigue Inventory, McGill Pain Questionnaire, and the Stroop attention concentration test. Scores were assessed 8 weeks before treatment; at randomization; after 8, 16, and 24 weeks of treatment; and 2 weeks later.
    RESULTS: Clinical global impression of change after treatment showed considerable improvement in 59% of the patients in the acetylcarnitine group and 63% in the propionylcarnitine group, but less in the acetylcarnitine plus propionylcarnitine group (37%). Acetylcarnitine significantly improved mental fatigue (p =.015) and propionylcarnitine improved general fatigue (p =.004). Attention concentration improved in all groups, whereas pain complaints did not decrease in any group. Two weeks after treatment, worsening of fatigue was experienced by 52%, 50%, and 37% in the acetylcarnitine, propionylcarnitine, and combined group, respectively. In the acetylcarnitine group, but not in the other groups, the changes in plasma carnitine levels correlated with clinical improvement.
    CONCLUSIONS: Acetylcarnitine and propionylcarnitine showed beneficial effect on fatigue and attention concentration. Less improvement was found by the combined treatment. Acetylcarnitine had main effect on mental fatigue and propionylcarnitine on general fatigue.
    very nice little study...thank you
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    I have used ALCAR for the past year and just recently changed to PLCAR to see if I notice any difference (Keep in mind that I stack this with Piracatem and Choline). After two weeks of using it, I have noticed that I feel more alert and less mentally tired. Not sure if this is due to the fact that I just changed over to it, but I will continue to monitor.

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    Does anyone whant to buy some alcar from me? I personally don't like the stuff. It maks me tired, even at the lowest dosage, even with choline. I probably have 80 grams left, so message me if you whant it.

    I have to warn you that I'm not even sure how I would ship it yet.
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    I've been on PLCAR for 2 weeks @ 2g twice a day, it does seem to help burn fat a little but mainly it's an overall good feeling. Not a boost of energy, just a well rested feeling.

    Never tried ALCAR.
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    ALCAR geared for the brain
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    I've been on ALCAR for a while. 3g, 2x/day. Haven't noticed much honestly.
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    OK I am about to be a noob, I searched PLCAR even propionylcarnitine and only found Lcarnitine. Can someone help me find PLCAR as an actual supplement.
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    Quote Originally Posted by ABNRanger View Post
    OK I am about to be a noob, I searched PLCAR even propionylcarnitine and only found Lcarnitine. Can someone help me find PLCAR as an actual supplement.
    Strong 5 year bump, but I believe SNS has an ALCAR supplement. The only supp that I know that has PLCAR is DCP 2.0
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    Thanks will look at both products. I am looking to stack with sns x-gel hence my search.
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    There are still some SNS PLCAR bottles out there.
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    Quote Originally Posted by kbayne View Post
    There are still some SNS PLCAR bottles out there.
    I didn't know that, where?
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    Quote Originally Posted by Jackedjack View Post
    I didn't know that, where?
    Looks like TF Supplements still has some,

    http://www.tfsupplements.com/store/p...plcar-500.html


    SNS discontinued PLCAR based on low sales. It's really too bad. I really love the stuff. Long term for fat loss it's great. Also it seemed to give me a physical type of energy not noticed from any other supplement. It's subtle but its there and you definitely notice a difference after you stop when you've been taking it a while. Really wish they would bring the stuff back.
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    Nutraplanet sell their own brand, 100g tubs of PLCAR
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    GPLC seems easier to find than PLCAR. Any functional difference between the two? Does the glycine component make any difference other than providing glycine, i.e. PLCAR + glycine?
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    Quote Originally Posted by test112 View Post
    GPLC seems easier to find than PLCAR. Any functional difference between the two? Does the glycine component make any difference other than providing glycine, i.e. PLCAR + glycine?

    I've tried both. The Glycine version just isn't the same. It puts me straight to sleep. I'd never use it again.
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    If fat loss is your goal, yet you want to reap the benefits of added mental boost and non-stim energy then ALC (Acetyl-L-Carnitine) is the right approach IMO.
    There are studies that point to the addition of CLA (Cunjugated Linoeic Acid) being the right approach. The two work synergisticly.

    Do your research and then research some more and make an educated choice.
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    Quote Originally Posted by test112 View Post
    GPLC seems easier to find than PLCAR. Any functional difference between the two? Does the glycine component make any difference other than providing glycine, i.e. PLCAR + glycine?
    You can just buy glycine and combine it with PLCAR to make GPLC.
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    Quote Originally Posted by Synapsin View Post
    You can just buy glycine and combine it with PLCAR to make GPLC.
    How would you dose the Glycine say if i was dosing 1g-1.5g PLCAR twice a day?
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    Quote Originally Posted by Synapsin View Post
    You can just buy glycine and combine it with PLCAR to make GPLC.
    That's kinda the opposite of what I was asking - I wouldn't buy it as a source of glycine, more it was whether the glycine component changed the PLCAR component's effects.
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    Quote Originally Posted by T-Bone View Post
    I've tried both. The Glycine version just isn't the same. It puts me straight to sleep. I'd never use it again.
    And that's the thing - I like glycine specifically as a sleep aid. Wouldn't TMG theoretically have the same issues?

    But I've used GPLC and haven't found it to be sedating. I was more wondering if the PLCAR- like benefits are identical despite the glycine.
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    Quote Originally Posted by Chub View Post
    How would you dose the Glycine say if i was dosing 1g-1.5g PLCAR twice a day?
    I wouldn't bother doing this, PLCAR is good enough.

    Quote Originally Posted by test112 View Post
    That's kinda the opposite of what I was asking - I wouldn't buy it as a source of glycine, more it was whether the glycine component changed the PLCAR component's effects.
    Yes it would.

    Quote Originally Posted by test112 View Post
    And that's the thing - I like glycine specifically as a sleep aid. Wouldn't TMG theoretically have the same issues?

    But I've used GPLC and haven't found it to be sedating. I was more wondering if the PLCAR- like benefits are identical despite the glycine.
    IMO GPLC is not worth the expense, much better products out there. Also interesting to note that GPLC has a u-curve that's small, so some of the common doses I see people using are actually bad for performance.
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    Quote Originally Posted by Synapsin View Post
    http://www.ncbi.nlm.nih.gov/pubmed/20979659
    This study? Long-term glycine propionyl-l-carnitin... [J Int Soc Sports Nutr. 2010] - PubMed - NCBI

    I love it when the titles have "paradoxical" in them.

    That would indeed be pretty funny if guys were blowing out cash on 4.5g doses of GPLC and actually worsening their performance versus control, especially if they're going right past a 1.5g beneficial dose.
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    Quote Originally Posted by Nyrin View Post
    This study? Long-term glycine propionyl-l-carnitin... [J Int Soc Sports Nutr. 2010] - PubMed - NCBI

    I love it when the titles have "paradoxical" in them.

    That would indeed be pretty funny if guys were blowing out cash on 4.5g doses of GPLC and actually worsening their performance versus control, especially if they're going right past a 1.5g beneficial dose.
    Wasn't that supposed to be due to the pump from the GPLC hindering knee extension during the cycle erg test?
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    I remember taking a pre-workout with the glycine version and just wanting to go to sleep. PLCAR on the other hand is awesome stuff, and works well on an empty stomach pre-workout.
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    Quote Originally Posted by T-Bone View Post
    I remember taking a pre-workout with the glycine version and just wanting to go to sleep. PLCAR on the other hand is awesome stuff, and works well on an empty stomach pre-workout.
    I'd love to try it but it's not very easy to find! Only a few places seem to stock it. Reckon you guys could get nutra to sell it again? My options are limited as I'm not in the states.
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    Quote Originally Posted by test112 View Post
    I'd love to try it but it's not very easy to find! Only a few places seem to stock it. Reckon you guys could get nutra to sell it again? My options are limited as I'm not in the states.

    Tf supplements ships internationally,

    http://www.tfsupplements.com/store/p...plcar-500.html


    I wish I could get SNS to bring it back again.
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    I think I would prefer ALCAR to PLCAR anyway for the acetyl donor group.
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    Quote Originally Posted by test112 View Post
    I'd love to try it but it's not very easy to find! Only a few places seem to stock it. Reckon you guys could get nutra to sell it again? My options are limited as I'm not in the states.
    Unfortunately PLCAR is as underrated as they come and so it is doubtful it will make a come back in our line.
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    Quote Originally Posted by Jiigzz View Post
    Unfortunately PLCAR is as underrated as they come and so it is doubtful it will make a come back in our line.
    Didn't realise you guys had discontinued it! Nutra's always out as well.

    In that case, apart from residual SNS stock, PLCAR is currently all but unavailable to consumers at a retail level.
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    I personally "feel" alcar more. I get a nice cognitive boost when I take it, and i definitely notice it when its not in my stack. I typically take around 2g per day, usually with my carb meal. Studies show intramuscular carnitine concentrations wont increase (with supplementation) without the presence of insulin, so something to keep in mind.
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    Quote Originally Posted by kevinhy View Post
    I personally "feel" alcar more. I get a nice cognitive boost when I take it, and i definitely notice it when its not in my stack. I typically take around 2g per day, usually with my carb meal. Studies show intramuscular carnitine concentrations wont increase (with supplementation) without the presence of insulin, so something to keep in mind.
    What about dosing with Bcaa's since leucine itself elicits an insulin response?
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    Quote Originally Posted by money0351 View Post
    What about dosing with Bcaa's since leucine itself elicits an insulin response?
    shiiiiitt, Hows it going man!?

    I'm honestly not sure, I dont think they elicit "enough" of an insulin response to be honest. How many times have you been fasted, drank aminos with a high leucine content and went hypoglycemic? If it was causing a strong response everyone would need to have glucose with their BCAAs to prevent themselves from passing out.
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    Quote Originally Posted by kevinhy View Post

    shiiiiitt, Hows it going man!?

    I'm honestly not sure, I dont think they elicit "enough" of an insulin response to be honest. How many times have you been fasted, drank aminos with a high leucine content and went hypoglycemic? If it was causing a strong response everyone would need to have glucose with their BCAAs to prevent themselves from passing out.
    Pretty great bro, how did the move go?

    IIRC I read that leucine itself is very insulinogenic, however that the results are very short lived. I didn't know that if, lets say, a bolus containing 15g of a BCAA/EAA (like amino IV) with a gram of ALCAR during "fasted training" would saturate carnatine levels comparable to consuming with carbohydrates.
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    Quote Originally Posted by money0351 View Post
    Pretty great bro, how did the move go? IIRC I read that leucine itself is very insulinogenic, however that the results are very short lived. I didn't know that if, lets say, a bolus containing 15g of a BCAA/EAA (like amino IV) with a gram of ALCAR during "fasted training" would saturate carnatine levels comparable to consuming with carbohydrates.
    Yeah it huge but very short lived. That's a good question. During prep I added LCLT to my intra that was mostly EAA with a high leucine content, I got pretty ripped soooo yeah? Lol can't hurt?
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    Quote Originally Posted by ABNRanger View Post
    OK I am about to be a noob, I searched PLCAR even propionylcarnitine and only found Lcarnitine. Can someone help me find PLCAR as an actual supplement.
    mod edit: nice try.
  

  
 

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