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Bulk powders can be used for multiple purposes. They are an excellent way to save money on supplements, and can also be used in making supplements for transdermal, sublingual, nasal, or other forms of administration. Following are some of the ways to use supplement powders.
A. Measure out the desired amount of powder and mix in with a beverage.
This is the simplest method. However, it should be noted that some powders do not mix very easily, and also that some powders have a taste that is difficult to hide. The best way to hide the taste of most powders is with a beverage high in citric acid such as Kool-Aid. Mixing in with a protein shake can hide the taste of some powders. The amount per ¼ teaspoon is given with each bulk powder, but make note of the fact that ¼ teaspoon is not necessarily the recommended dose for many powders. Sometimes, this is multiple doses, and other times the dose will be much larger. Make sure to establish the standard dosage before using any powder. For more accurate measurement of doses, a scale is recommended, and if you plan on making a lot of your own supplements, it is well worth the investment.
You can take this idea further by mixing powders together. For example, take a 30 day supply of three bulk powders, add them together, and shake thoroughly. You should know how many grams of the mixture you want to take daily by adding up the total daily doses of the powders you used. You can then find out how many grams of the powder there are per teaspoon (or tablespoon, or any other measurement) using a scale, and calculate how many teaspoons you should take daily to get the desired dosage. Note that to get an even mixture, you need to shake up the ingredients quite well, with the container upside down (as some ingredients will tend to settle near the top, and this will help mitigate this). Some powders will clump together and not mix well, but most will mix adequately, and clumps can be broken apart. Because hot spots are possible, this method is not recommended with powders you want to avoid overdosing on, such as stimulants like yohimbine and caffeine. These should be taken separately.
For some ideas for powder mixtures, see the next section of this article.
B. Put the powder in capsules.
This option is useful for those who would rather take pills then mix powder in a drink a few times daily, and is especially convenient if doses are being taken throughout the day. It is also helpful for powders with a strong taste. To put powders in capsules, a Cap Em Quik and empty capsules can be used (these can be found in the capping supplies section of the store). The Cap Em Quik is very easy to use, and with a little practice, it takes 5-10 minutes per 50 capsules. The size 00 capsules are the best deal, as the 000 size capsules hold more but are disproportionately more expensive. If you are not going for pure volume, and want less material per capsule, the size 0 capsules also work well.
To tell how much of the supplement is in each capsule, just divide the quantity of powder used by the number of capsules it took to encapsulate all of the powder. For example, if you use 100 grams of powder, and end up with 180 capsules, there is about 550 mg of powder in each capsule (100 grams divided by 180). Another option is to weigh a few capsules with a scale, and take the average weight minus the weight of an empty capsule. A mixture of powders can also be made as described above and then put into capsules. The easiest way to do this is encapsulate all of the supplements you plan on taking for a certain period of time. For example, mix together a one month supply of each powder you plan on taking, put it all into capsules, then count the capsules and divide that number by 30 to get how many capsules you should take daily.
Trying to get a certain amount of an ingredient per capsule is more difficult, but can be done using a filler and some trial and error. Maltodextrin, or just about any other powder, can be used as filler. Mix the filler and the active substance together in a certain ratio (such as 50/50), and then make some capsules. Then find out the amount of powder in each capsule using one of the methods described above – by weighing the capsules or dividing the amount of powder used by the amount of capsules made. From this you can determine how much active is in each capsule, and then change the ratio of filler to active ingredient accordingly to get the desired amount in each capsule. Once you get an idea of the density of the filler you are using, this process becomes a lot easier.
C. Create an oral solution.
This is primarily useful for powders where small doses are required (such as yohimbine). To create and use an oral solution, you will need an oral syringe (these can be found at most pharmacies), a way of measuring liquid, and information on the solubility of the powder you are using (what it is soluble in, and how soluble it is). Yohimbine HCl is soluble in water, and distilled water as opposed to tap water is recommended. To create an oral solution, put a known amount of powder in a known amount of solvent. For example, adding one gram of yohimbine HCl to 200 mL of water will make a 5 mg/mL solution. This is then easy to dose with an oral syringe. Shaking the solution before each use is recommended.
D. Make a transdermal, sublingual, etc.
Many powders are much more effectively delivered through routes other than oral administration. Depending on the powder, transdermal, sublingual, intranasal, or other delivery methods may be superior to standard oral administration. This is particularly the case with hormone powders (which is all that will be covered here).
To make a transdermal with a hormone powder (these include prohormones, steroids, androstenetrione, formestane, and 7-keto-DHEA), the Dermabolics Transport Matrix is an effective delivery agent. Each bottle can hold a total of about 7 grams of hormone powder (sometimes more, depending on the powder), and it is as simple as adding the powder and then shaking vigorously. The saturation point can be increased by lightly heating it, but this is often more trouble than it is worth unless you have already accidentally added too much powder. The effective transdermal dose is usually about 1/4th to 1/3rd of the standard oral dose. For more information on transdermal administration, see the Transdermal Prohormone FAQ. Note that the Transport Matrix is designed specifically for hormone powders, so it may not be an effective carrier for other powders.
Another option with hormone powders is creation of a cyclodextrin complex for sublingual or intranasal delivery. This is done using hydroxypropyl-beta cyclodextrin powder. For further information on this form of delivery, see this article: HPBCD Basics.
A. Measure out the desired amount of powder and mix in with a beverage.
This is the simplest method. However, it should be noted that some powders do not mix very easily, and also that some powders have a taste that is difficult to hide. The best way to hide the taste of most powders is with a beverage high in citric acid such as Kool-Aid. Mixing in with a protein shake can hide the taste of some powders. The amount per ¼ teaspoon is given with each bulk powder, but make note of the fact that ¼ teaspoon is not necessarily the recommended dose for many powders. Sometimes, this is multiple doses, and other times the dose will be much larger. Make sure to establish the standard dosage before using any powder. For more accurate measurement of doses, a scale is recommended, and if you plan on making a lot of your own supplements, it is well worth the investment.
You can take this idea further by mixing powders together. For example, take a 30 day supply of three bulk powders, add them together, and shake thoroughly. You should know how many grams of the mixture you want to take daily by adding up the total daily doses of the powders you used. You can then find out how many grams of the powder there are per teaspoon (or tablespoon, or any other measurement) using a scale, and calculate how many teaspoons you should take daily to get the desired dosage. Note that to get an even mixture, you need to shake up the ingredients quite well, with the container upside down (as some ingredients will tend to settle near the top, and this will help mitigate this). Some powders will clump together and not mix well, but most will mix adequately, and clumps can be broken apart. Because hot spots are possible, this method is not recommended with powders you want to avoid overdosing on, such as stimulants like yohimbine and caffeine. These should be taken separately.
For some ideas for powder mixtures, see the next section of this article.
B. Put the powder in capsules.
This option is useful for those who would rather take pills then mix powder in a drink a few times daily, and is especially convenient if doses are being taken throughout the day. It is also helpful for powders with a strong taste. To put powders in capsules, a Cap Em Quik and empty capsules can be used (these can be found in the capping supplies section of the store). The Cap Em Quik is very easy to use, and with a little practice, it takes 5-10 minutes per 50 capsules. The size 00 capsules are the best deal, as the 000 size capsules hold more but are disproportionately more expensive. If you are not going for pure volume, and want less material per capsule, the size 0 capsules also work well.
To tell how much of the supplement is in each capsule, just divide the quantity of powder used by the number of capsules it took to encapsulate all of the powder. For example, if you use 100 grams of powder, and end up with 180 capsules, there is about 550 mg of powder in each capsule (100 grams divided by 180). Another option is to weigh a few capsules with a scale, and take the average weight minus the weight of an empty capsule. A mixture of powders can also be made as described above and then put into capsules. The easiest way to do this is encapsulate all of the supplements you plan on taking for a certain period of time. For example, mix together a one month supply of each powder you plan on taking, put it all into capsules, then count the capsules and divide that number by 30 to get how many capsules you should take daily.
Trying to get a certain amount of an ingredient per capsule is more difficult, but can be done using a filler and some trial and error. Maltodextrin, or just about any other powder, can be used as filler. Mix the filler and the active substance together in a certain ratio (such as 50/50), and then make some capsules. Then find out the amount of powder in each capsule using one of the methods described above – by weighing the capsules or dividing the amount of powder used by the amount of capsules made. From this you can determine how much active is in each capsule, and then change the ratio of filler to active ingredient accordingly to get the desired amount in each capsule. Once you get an idea of the density of the filler you are using, this process becomes a lot easier.
C. Create an oral solution.
This is primarily useful for powders where small doses are required (such as yohimbine). To create and use an oral solution, you will need an oral syringe (these can be found at most pharmacies), a way of measuring liquid, and information on the solubility of the powder you are using (what it is soluble in, and how soluble it is). Yohimbine HCl is soluble in water, and distilled water as opposed to tap water is recommended. To create an oral solution, put a known amount of powder in a known amount of solvent. For example, adding one gram of yohimbine HCl to 200 mL of water will make a 5 mg/mL solution. This is then easy to dose with an oral syringe. Shaking the solution before each use is recommended.
D. Make a transdermal, sublingual, etc.
Many powders are much more effectively delivered through routes other than oral administration. Depending on the powder, transdermal, sublingual, intranasal, or other delivery methods may be superior to standard oral administration. This is particularly the case with hormone powders (which is all that will be covered here).
To make a transdermal with a hormone powder (these include prohormones, steroids, androstenetrione, formestane, and 7-keto-DHEA), the Dermabolics Transport Matrix is an effective delivery agent. Each bottle can hold a total of about 7 grams of hormone powder (sometimes more, depending on the powder), and it is as simple as adding the powder and then shaking vigorously. The saturation point can be increased by lightly heating it, but this is often more trouble than it is worth unless you have already accidentally added too much powder. The effective transdermal dose is usually about 1/4th to 1/3rd of the standard oral dose. For more information on transdermal administration, see the Transdermal Prohormone FAQ. Note that the Transport Matrix is designed specifically for hormone powders, so it may not be an effective carrier for other powders.
Another option with hormone powders is creation of a cyclodextrin complex for sublingual or intranasal delivery. This is done using hydroxypropyl-beta cyclodextrin powder. For further information on this form of delivery, see this article: HPBCD Basics.
