Creatine is a "methyl" compound?

[Jeff Rippe]

The chemical name for creatine is "N-Methyl-N-Guanylglycine".

Why is this "methyl" compound not toxic to the liver?

 

[motiv8er]

Hey Jeff,
While I am not certain of the answer to your question, I think creatine would better fit the supplements section. Thanks

 

[Jeff Rippe]

I placed it in the "Anabolics" forum because of the "methyl" question. Thought the visitors there would know the answer.

 

[Jblake]

Not all methyl bonds are harmful to the liver. We put all kinds of compounds in and on our bodies every day that are methylated in some way. Caffeine is a methylxanthine and there aren't millions of Americans dropping dead from their daily cups'o joe.

It's when a STEROID molecule is methylated that the detrimental effects can occur on the liver.

It's not actually the methylated compound that causes the harm, but the compounds that the 17 alpha alkylated steroid breaks down into. These are called 17-glucuronide metabolites. The way the body metabolizes these is what causes harm to the liver.

A good article to learn more:

http://www.mindandmuscle.net/mindandmuscle/magpage.php?issueID=37&artID=16

 

[thetimbomb]

creatine may contain a methyl bond but... i am quite sure it is neither an anabolic, nor a ph, nor a steroid. Have fun