The most underrated supplement : curcumin
03-07-2006 10:30 AM
The most underrated supplement : curcumin
Found on the life extension foundation site :
Believe it or not, curcumin has something in it that repairs muscle better than anything presently known. Derived from the spice turmeric, curcumin speeds recovery without injections or side effects. Although the data is preliminary, it appears that when curcumin is taken orally, it has the ability to home in on injured muscle. Once there, it changes the biochemistry of baby muscle cells, causing them to grow faster and clump together quicker to create new tissue. According to the study, curcumin caused muscle cells to fuse together twice as fast as they ordinarily would.
It’s not known exactly how curcumin works. Researchers do know, however, that curcumin suppresses a factor that influences growth factors. This factor, NF B (nuclear factor kappa B), plays a prominent role in immunity and cell growth. Immediately after muscle injury, the immune system dispatches cells to the area. Their job is to destroy old tissue and begin new construction. NF B is one of the lines of communication immune cells use to get things done. By influencing NF B, curcumin modulates the repair process.
The regeneration of muscle is a complex phenomenon. Curcumin works in part by changing the ar***** time and status of chemical messengers known as cytokines. Cytokines appear at the scene early on, and they have a powerful effect on inflammation and cell growth. A cytokine known as IL-6 (interleukin-6), for example, makes muscle cells multiply. Another one called TNF (tumor necrosis factor) keeps cells from growing up, developing. By suppressing one, and enhancing the other, curcumin can speed things up.
The authors of the study believe that curcumin works by other mechanisms that probably involve growth factors, but this has not been proven yet. In other attempts to make muscles regenerate, researchers have tried injecting synthetic growth factors or transplanting myoblasts–all with limited success. Curcumin seems to be a much safer, more effective treatment–at least in the early stages. The effects of curcumin are felt early on–right after injury when the body first sends out the repair squads. So if you want to try curcumin for muscle regeneration, make sure you take it as soon as the injury occurs. The authors of the study predict that curcumin may be useful not only for accidental injuries or sports, but also to help repair surgical damage.
Thaloor D, et al. 1999. Systemic administration of the NF- B inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am J Physiol 277(2 pt 1):C320-29.
Other links about curcumin properties :
...Many documented studies :
Maybe one of the best best things you can take if you're interested in :
-lowering your cholesterol levels
-prevent (or even fight) cancer
-get better muscular recovery after workouts
-anti-inflammatory activity (same as aspirin without sides)
-improving gastro intestinal tract (did you say gaz from whey protein ?? )
and many others...
03-07-2006 10:48 AM
Good article. I just googled it to learn more about it. Tumeric (curcumin) is good for alot of things, surprising. I'll be adding it to my arsenal for it's benefits here soon. Thanks
03-07-2006 11:09 AM
Yeah, definitely a good addition and its cheap, so why not right.
03-07-2006 11:11 AM
In the scientific community, the wide-ranging benefits of curcumin are well known. Recently (with further support soon to come ), several 'anti-cancer' benefits of curcumin have been revealed.
Originally Posted by jeffas66
03-07-2006 02:10 PM
Thanks for the info. Have you ever taken curcumin? And if so, did you notice anything from it?
03-07-2006 02:33 PM
My dad and mom take it, (Turmeric) they get the powder from any grocery store. It tastes pretty bad, but my dad said his stomach ailments have improved very much so since he started taking it 2 times a day.
03-07-2006 02:53 PM
This comes from the place where I get my bulk herbs from. http://www.mountainroseherbs.com/learn/tumeric_root.php
A volatile oil in the spice is as effective in relieving pain, under laboratory conditions, as equal amounts of steroids. Nice.
03-07-2006 11:49 PM
I've been taking turmeric for about a year for general wellness. Have only done one PH cycle and no gear during that time. I wasn't attributing any muscle-related benefits to it, although I have noticed that injuries and soreness go away faster than they usually did-- but I attributed that to CEE, because the recovery effects were similar to when I first used creatine monohydrate.
03-08-2006 12:51 AM
Curcumin works great when combined with bioperine. 500 mg twice a day does wonders for my cholesterol.
03-09-2006 04:53 PM
I think Ryanism used Circumin to lower his BP on his M-TRN cycle. So far it:
1) Helps repair damaged muscles
2) Acts as an anti-Cancer agent (maybe)
3) Cures stomach ailments
4) helps cholesterol levels
5) Lowers BP
sounds under rated to me.....
03-11-2006 12:36 AM
looks like a good supp to add
03-11-2006 01:58 PM
I found this....
Clusters of men on Internet prostate cancer support groups (notably Don Cooley's lists) began seriously experimenting with turmeric to cope with a troublesome side-effect of androgen-suppression therapy, gynecomastia
(sore swollen breasts). Most men who take antiandrogen drugs like Flutamide (Eulexin) or Casodex experience this breast swelling, which can be painful. Gynecomastia can occur also with use of finasteride(Proscar), prescribed for BPH (benign growth of the prostate) and now under discussion as a chemo-preventive for prostate cancer. Before starting Casodex some patients opt to receive a brief course of radiation to the breasts. Others have tried low-dose tamoxifen, which raises levels of circulating estradiol. Then there are the turmeric warriors, who report that dietary intake of turmeric (in salads, soups and sandwiches made with fresh root) and use of curcumin paste externally brings some relief.
03-11-2006 07:54 PM
I've used it for a while as an antioxiant, but I never knew about this. Maybe I'll start combining it with CEE when I cap the CEE.
03-11-2006 07:59 PM
Wow might have to give this stuff a try.
03-11-2006 08:14 PM
I think I just threw up in my...mouf yep, I did.
Originally Posted by Chippewa
03-11-2006 08:26 PM
I just capped a bunch of tumeric (about 80 cents per ounce at the herb store) in some OOO caps. About 15-20 minutes after taking a single cap I could notice that my lungs and sinuses were opening up and this lead to less restricted breathing. I almost always have some low grade allergies going on and my sinuses are rarely fully open.
03-11-2006 08:54 PM
Originally Posted by methusaleh
As is the case with so many herbs, turmeric should be used in moderation. Too much turmeric for too long can cause stomach distress. Since turmeric is included in Ayurvedic formulas for birth control, women trying to become pregnant should limit their consumption of the herb, and it should be avoided while pregnant. Excessive use of turmeric should also be avoided in people with congestive heart failure. The curcumin in turmeric activates a gene called p53. This gene deactivates cancer cells, but it also deactivates damaged cells in the heart.
03-11-2006 11:32 PM
Does the herb that you find at the grocery store provide these benefits, or is it a different form that is needed? Also, what dosages are recommended?
03-12-2006 12:09 AM
I've heard it's also good for the joints but never really looked into it.
03-12-2006 02:49 AM
The best is to take a standardised extract with bioperine, because the bioavaibility is low.
Originally Posted by jarhead
Sabinsa's stuff is very good (the "C3" stuff) but I think you could find another source for it. I don't really know about groceries, because I have to import it from USA : prices are much higher in France for supplements (even with shipping charges...)
Something like 500mg of a 95% extract 2 x a day is enough I believe. Anything over 3-4g/d could be too much for sides (but I have to find a report for this...)
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