glutamine i dont like before, during, after, before bed or anytime (ha). as for creatine, if you're taking only one serving (5-10grams) after your workout, the preworkout really isnt necessary. I would say no, and save some servings. if you're using glutamine and creatine however (seriously though, if you're taking a good amount of protein from powder and other whole food source with decent amount of glutamine... glutamine supplementaion isnt necessary) i would take the glutamine before your workout and keep the creatine afterwords. Sage