neodvl
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Is stacking x-factor with lean xtreme ideal/beneficial no? Any input on this?
Thanks a lot
Mike
Thanks a lot
Mike
It will not hurt you at all and both are solid productsIs stacking x-factor with lean xtreme ideal/beneficial no? Any input on this?
Thanks a lot
Mike
And why do you think that have you tried it or is that just your opnionimo,x-factor is trash.
Arachnidonic acid is the source compound of practically all prostaglandins.your body has tons of it already in circulation.therefore,you don't create any extra prostaglandins of any type by taking in morearachidonic acid. rendering this product pretty much useless over priced hype.And why do you think that have you tried it or is that just your opnion
max von
Skepticism is great H8duke.. I applaud your interest in investigating a supplement before simply taking it and accepting the marketing claims. If every consumer were like you, ****, there would be few **** pushers out there, wouldn't there?Arachnidonic acid is the source compound of practically all prostaglandins.your body has tons of it already in circulation.therefore,you don't create any extra prostaglandins of any type by taking in morearachidonic acid. rendering this product pretty much useless over priced hype.
Provide a link please so we can examine the study. It is afterall only 1 study and we all know how studies can be made to skew in favor of a particular hypothesis or the results be interpretted to come to an invalid conclusion.Skepticism is great H8duke.. I applaud your interest in investigating a supplement before simply taking it and accepting the marketing claims. If every consumer were like you, ****, there would be few **** pushers out there, wouldn't there?
On the note of discovery, I am sure you will apprecite the paper Clin Pharmacol Ther. 1975 Nov;18(5 Pt 1):521 "Increased arachidonate in lipids after administration to man: effects on prostaglandin biosynthesis.". It does show that PG biosynthesis can be augmented by taking oral AA. FWIW, I have been extensively researching this product for years, and feel it is going to be regarded as my greatest accomplishment in this field. It is no snake oil. I hope now that I have presented some data in contrary you might be interested in investigating this supplement a little further. I have a feeling you will be very interested in what you learn about it. If you have Q's, please feel free to post them.
Thanks, and best.
Interesting study, but it really doesn't have much relevance to how AA loading actually works in exercising humans. We have people winning shows using X-Factor for contest prep, so the thought that it might make you fat is a little counterintuitive at this point. I've heard the same before when it first came out, but that has not proven to be the case - quite the opposite.Provide a link please so we can examine the study. It is afterall only 1 study and we all know how studies can be made to skew in favor of a particular hypothesis or the results be interpretted to come to an invalid conclusion.
In the meantime I'm looking up studies on arachidonic acid administration, as well as other factors which may increase or decrease arachidonic acid in humans.
A little update...
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15304745&query_hl=2
This is not particularly about achidonaic acid, but it is about prostaglandins. It is about prostaglandins which cause adipogensis at the PPARgamma receptor. Arachidonic acid is the source compound of ALL prostaglandins in our body IIRC. Therefore, if increasing AA can increase PGF2a, it goes to reason that it increases other prostaglandins as well. Why is this important? Because it shows us that by merely showing that oral AA administration increases PGF2a you do not adequately prove effectiveness of AA for fat loss. This is because there may, and very likely, is a balance between synthesis of PGF2a and other prostaglandins manufactured from orally administered AA. Thus no noticeable change may occur, or worse, AA administration may result in an overabundance of adipocyte genesis caused by other prostaglandins that supercedes adipocyte necrosis caused by PGF2a.
Translation: no one should be satisfied with proof of efficacy until sufficient studies show that oral arachidonic acidadministration causes FAT LOSS. Not merely increases PGF2a levels.
Yes, I see where you are coming from, and you are 100% right for wondering about this. We don't recommend it to people with conditions like arthritis for this reason - it can exacerbate discomfort. Cox-2 is an enzyme (cyclooxygenase). AA increases the COX-2 products of AA, which includes anabolic PGF2alpha (the 2 denotes dienolic PG synthesis - or 2 series).Will these studies report adverse events and likely side effects? For example, AA administration is likely to increase COX-2 synthesis (as well as a host of other inflamatory factors and pro-inflamatories) which in turn may cause arthritic inflamation, and for those with arthritis may exacerbate symptoms. As we know, many of use have already problems with joint pain just from the exercise we do. Many a bodybuilder has fallen by the wayside due to abuse of NSAIDs and other painkillers used in order to train around the pain. So you can understand why this would be a major concern.
ADMA is an NO synthesis inhibitor, and may be detrimental to the body by effecting/reducing blood flow and endothelial relaxation. AA has an opposite effect, namely increasing blood flow by supporting NO synthesis (via PGE2). It has an arginine type effect, opposite of ADMA. I know of no study looking at AA and ADMA, but suspect you are not going to see an issue given the obvious vasodilatory nature of X-Factor.Are you checking for asymmetric dimethyl arginine increases? Prostaglandin levels have been linked to an increase in ADMA which is a major predictor for heart disease. In fact, DHA and EPA have been shown to lower many inflamatory prostaglandins, in turn decreasing ADMA. The current theory is that this is the manner by which EPA and DHA help cardiovascular health (and by which many other polyunsaturated fats do).
ADMA has been shown to be a better predictor than things like blood pressure and cholesterol, since there are a number of people who have high blood pressure and high cholesterol yet do not develop heart problems for many many years if at all.
That was my question too, really easy to say a producst is no goodSo you haven't tried it then?
Please do a log on here. I appreciate the fact that you are going to use the product. Keep me posted on how you do and if I can be of any help please let me knowI'm actually excited to try this product after my winter bulk. Around Feb/March I will start a detailed log.