Why isn't Pregnenolone more popular?

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  1. Why isn't Pregnenolone more popular?


    Seems to me like one of the few 'wow this works' supplements at a low price range, and the list of benefits and quality of reviews suggests that this should be more prominent, but I hardly hear about it. I am aware there are some slight side effects, but nothing that really concerned me.

    Any thoughts on Pregnenolone? A must try? I'm 36, young enough to see a benefit?



    Thank you in advance, gentlemen!


  2. IMO I think it is because it is not one of those Supps that give you a rush of energy, so people donít see the overall value in it. Itís more of a sustained energy level and effects.
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  3. Because itís the mother hormone. It converts to test, estrogen and cortisol depending on your needs/state
    Antaeus Labs Rep

  4. Preg is a pretty potent neurosteroid but the problem is the absorbability. Like any exogenous hormone, it can be a good thing if you're deficient in it but unwanted side effects/conversion could possibly arise.

  5. several guys using preg to cut back on stims...seems to be pretty effective
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  6. Quote Originally Posted by thebigt View Post
    several guys using preg to cut back on stims...seems to be pretty effective
    Diesel Nut uses it in a few their supplements and you do feel the effects .

  7. mr. godstregth provided this from dr crisler -

    Much of Pregnenolone’s benefits are because it is converted in the body to Allopregnenolone, which is like Nature’s benzodiazepine (i.e. Valium, Xanax, Ativan). That is why it can be so effective (and safe!), for treating serious issues such as anxiety, and depression. In fact, Pregnenolone was routinely—and very effectively—employed to treat anxiety, depression, and adrenal insufficiency in the United States in the 1930’s and 40’s....To treat anxiety with oral PREG (hopefully, the Sustained Release version), take right before going to bed at night. We usually start with 30-50mg. IF you are not groggy in the morning, and are still suffering anxiety during the day, try taking a similar dose with breakfast. Some people can only tolerate 10mg, once per day. Others use as much as 300mg per day, in divided doses. Is PREG powerful? I’ve seen people go into a stupor on fairly low doses…don’t drive or operate machinery until you have tried it safely.
    i take 100mg at night per my dr for hrt - so if it has acute effect, i not notice it (although I take it actually around 7pm - still nothing noticeable) so its very individual dependent it seems. if it does as above, i wouldn't want it pre-workout, lol!

  8. Quote Originally Posted by DaeshDontSurf View Post
    mr. godstregth provided this from dr crisler -



    i take 100mg at night per my dr for hrt - so if it has acute effect, i not notice it (although I take it actually around 7pm - still nothing noticeable) so its very individual dependent it seems. if it does as above, i wouldn't want it pre-workout, lol!
    I recommend using iconic formulations transdermal preg and applying it in the morning.
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  9. Quote Originally Posted by thebigt View Post
    I recommend using iconic formulations transdermal preg and applying it in the morning.
    Can vouch as well. I used their preg and was pleasantly surprised.
    kaos weckt das beste in uns. ruhe in frieden bruder

  10. Quote Originally Posted by TheVenom View Post
    Can vouch as well. I used their preg and was pleasantly surprised.

    very cool!!!
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  11. Doesnít it increase estrogen?

  12. Quote Originally Posted by horizons View Post
    Doesnít it increase estrogen?
    Yes, but not enough to cause an issue.
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  13. Quote Originally Posted by cheftepesh1 View Post
    Yes, but not enough to cause an issue.
    agreed!!!

    my trt is 100mg weekly and no AI, I can use preg along with my trt and have no issues.
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  14. Quote Originally Posted by thebigt View Post
    agreed!!!

    my trt is 100mg weekly and no AI, I can use preg along with my trt and have no issues.
    Whatís the best brand?

    I am suspect to estrogen issues though. Very prone

  15. Quote Originally Posted by thebigt View Post
    I recommend using iconic formulations transdermal preg and applying it in the morning.
    only if you don't have the benzodiazepene effect, i would say, so test needed. if it is as dr crisler stated (for indiv that are effected that way), it would be like starting day with xanax :-)

  16. Quote Originally Posted by cheftepesh1 View Post
    Yes, but not enough to cause an issue.
    how much did it increase your estrogen from baseline reading?

  17. Quote Originally Posted by DaeshDontSurf View Post
    only if you don't have the benzodiazepene effect, i would say, so test needed. if it is as dr crisler stated (for indiv that are effected that way), it would be like starting day with xanax :-)
    When I tried it a while back, the effect varied based on how it was taken. Oral pregnenolone was very calming/sedating. However, sublingual was very stimulating. Never tried transdermal.

  18. Quote Originally Posted by jarrellt67 View Post
    When I tried it a while back, the effect varied based on how it was taken. Oral pregnenolone was very calming/sedating. However, sublingual was very stimulating. Never tried transdermal.
    Transdermal wasn't exactly stimulating as it was awakening. For me it was like having a full battery with a higher capacity, instead of a regular battery that's just pumping more amps.

    Sorry if that doesn't make sense, but the clarity and sense of wellbeing is hard to explain with normal descriptors.
    kaos weckt das beste in uns. ruhe in frieden bruder

  19. Quote Originally Posted by horizons View Post
    What’s the best brand?

    I am suspect to estrogen issues though. Very prone
    if estrogen is a worry then I suggest dermacrine-it has both preg and dhea plus a mild anti-aromatase added.
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  20. Quote Originally Posted by TheVenom View Post
    Transdermal wasn't exactly stimulating as it was awakening. For me it was like having a full battery with a higher capacity, instead of a regular battery that's just pumping more amps.

    Sorry if that doesn't make sense, but the clarity and sense of wellbeing is hard to explain with normal descriptors.
    sounds like you enjoy it as much as I do!!!

    thanks for sharing.
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  21. Quote Originally Posted by thebigt View Post
    if estrogen is a worry then I suggest dermacrine-it has both preg and dhea plus a mild anti-aromatase added.
    This is exactly my worry when I think about ever experimenting with it for lethargy and anxiety issues I suffer. Ashwaghanda seemed to work , but it also made me feel a bit “off” if that makes sense. I think it actually made my anxiety worse but with the relaxing effects of Ashw, I couldn’t tell. Loved the body composition effects , though.

  22. Quote Originally Posted by Iwilleattuna View Post
    This is exactly my worry when I think about ever experimenting with it for lethargy and anxiety issues I suffer. Ashwaghanda seemed to work , but it also made me feel a bit “off” if that makes sense. I think it actually made my anxiety worse but with the relaxing effects of Ashw, I couldn’t tell. Loved the body composition effects , though.
    dermacrine sounds like better option over solo preg for this reason...



    do some research, many guys find Invictus very good for anxiety and is also excellent for body composition.


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    good luck!!!
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  23. Quote Originally Posted by thebigt View Post
    if estrogen is a worry then I suggest dermacrine-it has both preg and dhea plus a mild anti-aromatase added.
    Forgive my stupidity but doesnít DHEA also increase estrogen

    I canít stand anti-aromatase supplements. Always get the worst side effects

    Maybe Iíll give a oral a go

  24. Quote Originally Posted by horizons View Post
    Forgive my stupidity but doesnít DHEA also increase estrogen
    Broadly speaking, I guess the answer is yes. DHEA is often looked at as a precursor hormone, it can be converted into many sex hormones. It wonít necessarily increase estrogen, but itís similar to taking testosterone. While testosterone itself doesnít ďincreaseĒ estrogen, it provides substrate for aromatase, which can of course lead to an increase in estrogen.

  25. Quote Originally Posted by TheVenom View Post
    Transdermal wasn't exactly stimulating as it was awakening. For me it was like having a full battery with a higher capacity, instead of a regular battery that's just pumping more amps.

    Sorry if that doesn't make sense, but the clarity and sense of wellbeing is hard to explain with normal descriptors.
    I made similar observations.
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