There are several forms of phosphatidylcholine supplements. Typical commercial lecithin supplements contain 20 to 30% phosphatidylcholine. Softgel capsules containing 55% and 90% phosphatidylcholine are available. Liquid concentrates containing 3 grams of phosphatidylcholine per 5 milliliters (one teaspoon) are also available.
Recommended doses range from 3 to 9 grams of phosphatidylcholine daily in divided doses.
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Phosphatidylcholine has been used to lower serum cholesterol levels, based on the premise that lecithin cholesterol acyltransferase (LCAT) activity has an important role in the removal of cholesterol from tissues. A few studies have shown reduction in serum cholesterol with phosphatidylcholine intake. The results were quite modest, and most studies have not shown any significant cholesterol-lowering activity.
