Inositol Hexaphosphate (IP6) and hair - AnabolicMinds.com

Inositol Hexaphosphate (IP6) and hair

  1. Senior Member
    rrgg's Avatar
    Join Date
    Feb 2004
    Age
    41
    Posts
    1,018
    Rep Power
    638

    Reputation

    Inositol Hexaphosphate (IP6) and hair


    I saw somewhere that a study showed inositol hexaphosphate plus some B vitamins helped arrest or regrow hair in some balding patients. Does anyone have the actual study on this? Or know the dosing that was used? Thanks.

  2. New Member
    charliewat's Avatar
    Join Date
    Oct 2004
    Age
    34
    Posts
    131
    Rep Power
    186

    Reputation

    Will this stuff help me grow a Mustache my brother is 35 and still does not have one.
  3. New Member
    WhutEvr's Avatar
    Join Date
    Jan 2005
    Age
    54
    Posts
    329
    Rep Power
    282

    Reputation

    Haven't seen anything about hair regrowth.

    Here's what I did find:
    http://www.pdrhealth.com/drug_info/n...ino_0333.shtml
    Inositol Hexaphosphate

    DESCRIPTION

    Inositol hexaphosphate, also known as phytate, is a component of most cereal grains and seeds, occurring in conjunction with plant fiber, and is a source of myo-inositol in the diet. Inositol hexaphosphate is responsible for storing more than 80 percent of the total phosphate in cereals and legumes. Phytate has strong chelating power for doubly charged metal ions, such as magnesium, calcium and zinc. Some studies suggest that phytate may slow tumor growth rates.

    Inositol hexaphosphate, in addition to being known as phytate, is known as myo-inositol hexaphosphate, and myo-inositol 1,2,3,4,5,6-hexakisphosphate. Inositol hexaphosphate is abbreviated as InsP6 and sometimes as IP-6. The structural formula is:


    Inositol hexaphosphate
    ACTIONS AND PHARMACOLOGY

    ACTIONS

    Inositol hexaphosphate is a putative antiproliferative agent and may have antioxidant activity.

    MECHANISM OF ACTIONS

    Some speculate that inositol hexaphosphate's possible antiproliferative activity is due to its chelating divalent cations which may be important for tumor growth. Others speculate that inositol hexaphosphate, along with inositol, are metabolized to inositol triphosphates, which are believed to be involved in cell signaling and regulating cell growth, and that this may underlie its possible effects. Chelation by inositol hexaphosphate of ferrous cations could inhibit the Fenton reaction, a reaction which generates reactive oxygen species. Enhancement of natural killer cell activity is offered as still another speculative mechanism.

    PHARMACOKINETICS

    It is unclear how much inositol hexaphosphate is absorbed in humans following ingestion. Inositol hexaphosphate may, in part, be hydrolyzed to myo-inositol. (See myo-inositol.)

    INDICATIONS AND USAGE

    There is preliminary evidence that inositol hexaphosphate may eventually find some use in the treatment of some cancers.

    RESEARCH SUMMARY

    A few studies performed in vitro and in animal models suggest that inositol hexaphosphate inhibits some cancers, specifically epithelial cancers, including breast and colon cancers. It has also significantly inhibited human rhabdomyosarcoma in an animal model. More research is needed to see whether this substance can play a role in the clinical treatment of some cancers. There is some epidemiologic data suggesting that dietary phytate may have chemopreventive activity.

    CONTRAINDICATIONS, PRECAUTIONS, ADVERSE REACTIONS

    CONTRAINDICATIONS

    None known.

    PRECAUTIONS

    Supplemental inositol hexaphosphate should be avoided by pregnant women and nursing mothers, due to lack of long-term safety studies.

    ADVERSE REACTIONS

    No significant adverse effects were noted in one report on the use of a daily dose of 8.8 grams of inositol hexaphosphate taken for several months.

    INTERACTIONS

    Inositol hexaphosphate may form chelates with divalent cations such as calcium, magnesium, manganese, zinc, copper and iron found in foods, if taken with foods or nutritional supplements containing these elements. It may also interact with food proteins.

    OVERDOSAGE

    No reports of overdosage.

    DOSAGE AND ADMINISTRATION

    None recommended.

    LITERATURE

    Graf E, Eaton JW. Antioxidant function of phytic acid. Free Rad Biol Med. 1990; 8:61-69.

    Jariwalla RJ, Sabin R, Lawson S, Herman ZS. Lowering of serum cholesterol and triglycerides and modulation by dietary phytates. J Appl Nutr. 1990; 42:18-28.

    Jariwalla RJ, Sabin R, Lawson S, et al. Effect of dietary phytic acid (phytate) on the incidence and growth rate of tumors promoted in Fisher rats by magnesium supplement. Nutr Res. 1988; 8:813-827.

    Porres JM, Stahl CH, Cheng W-H, et al. Dietary intrinsic phytate protects colon from lipid peroxidation in pigs with a moderately high dietary iron intake. Proc Soc Exp Biol Med. 1999; 221:80-86.

    Shamsuddin AM. Inositol phosphates have novel anticancer function. J Nutr. 1995; 125:725S-732S.

    Shamsuddin AM. Reduction of cell proliferation and enhancement of NK-cell activity. 1992. United States Patent Number 5,082,833.

    Vucenik I, Kalebic T, Tantivejkulk, Shamsuddin A. Novel anticancer function of inositol hexaphosphate. Inhibition of human rhabdomyosarcoma in vitro and in vivo. Anticanc Res. 1998; 18:1377-1384.
    •   
       

Similar Forum Threads

  1. 1-ad vs 4-ad and hair
    By comrade in forum Anabolics
    Replies: 36
    Last Post: 01-01-2007, 05:31 PM
  2. topical spiro and hair gel
    By corteztk1982 in forum Anabolics
    Replies: 18
    Last Post: 04-02-2004, 04:58 AM
  3. PH's and Hair loss
    By Bryan in forum Anabolics
    Replies: 32
    Last Post: 12-22-2003, 12:03 PM
  4. 1-test, 3 alpha and hair
    By captainbicept in forum Anabolics
    Replies: 1
    Last Post: 07-21-2003, 09:05 PM
  5. PH's and hair
    By kwantz2 in forum Anabolics
    Replies: 5
    Last Post: 03-07-2003, 01:01 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in