No libido and ED for 7 months after two weeks of Olympus Arimistane at 50 mg/week.

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tengopregunta

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Basically what the title says, everyone.

Two months ago, test was at 700 (300-1100) and E2 at 18 on the sensitive assay. Prolactin was high at 16 so I was on caber for one month. I'm 23 years old. Is Arimistane a DHT blocker? In a similar way to finasteride? Is this permanant? What can I do to fix this? Thyroids and other hormones look normal.

I feel tired, brain fog, gyno, nipples hurt, my balls are always high and tight and seem to have gotten smaller. My dick now has a curve to it as well. I'm not joking, everyone. Can someone suggest something? Does someone know something sinister about this product? Will time be my cure?

I've never ran steroids in the past. Only taken this product. Currently taking tribulus, I have pine pollen and tongkat underway.
 
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Basically what the title says, everyone.

Two months ago, test was at 700 (300-1100) and E2 at 18 on the sensitive assay. Prolactin was high at 16 so I was on caber for one month. I'm 23 years old. Is Arimistane a DHT blocker? In a similar way to finasteride? Is this permanant? What can I do to fix this? Thyroids and other hormones look normal.

I feel tired, brain fog, gyno, nipples hurt, my balls are always high and tight and seem to have gotten smaller. My dick now has a curve to it as well. I'm not joking, everyone. Can someone suggest something? Does someone know something sinister about this product? Will time be my cure?

I've never ran steroids in the past. Only taken this product. Currently taking tribulus, I have pine pollen and tongkat underway.
It’s in your head
 
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I have a feeling that arimistane messes with the 5ar. Exemestane binds to 5ar. Accutane does too. They all have this "tane" suffix. Are there any prohormones out there that raise my DHT but are not extremely suppressive and wouldn't require clomid PCT? I'm thinking about something like R-andro.

Thoughts, anyone?
 
iamyourfather

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Basically what the title says, everyone.

Two months ago, test was at 700 (300-1100) and E2 at 18 on the sensitive assay. Prolactin was high at 16 so I was on caber for one month. I'm 23 years old. Is Arimistane a DHT blocker? In a similar way to finasteride? Is this permanant? What can I do to fix this? Thyroids and other hormones look normal.

I feel tired, brain fog, gyno, nipples hurt, my balls are always high and tight and seem to have gotten smaller. My dick now has a curve to it as well. I'm not joking, everyone. Can someone suggest something? Does someone know something sinister about this product? Will time be my cure?

I've never ran steroids in the past. Only taken this product. Currently taking tribulus, I have pine pollen and tongkat underway.
maybe speak to you doctor and tell him whats going on?! i would search for an endocrinologist and ask him whats the best way to treat your problem. anyone in this forum can just guess but no one knows whats really going on.
 
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maybe speak to you doctor and tell him whats going on?! i would search for an endocrinologist and ask him whats the best way to treat your problem. anyone in this forum can just guess but no one knows whats really going on.
I've spoken to two already. They both just gave me viagra. They had no idea what's up and that time will tell.

I really could use your guys' advice. Your more experts on this than I am since I've never taken anabolics. What would you do in this case?
 
iamyourfather

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I've spoken to two already. They both just gave me viagra. They had no idea what's up and that time will tell
you spoke to two normal doctors or to two endocrinologists? only a specialist could help you. if you already asked two of them, go and search for a third one!
 
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you spoke to two normal doctors or to two endocrinologists? only a specialist could help you. if you already asked two of them, go and search for a third one!
I've spoken to two endocrinologists. The thing is, money is short man! These docs are expensive. And the bloodwork is everything they care about and it looks practically normal. I fear I've done something epigenetically.
 
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No it's not. I don't have morning wood and I can't jerk off even, sometimes.
If your hormones levels are what you posted them at then YES, it’s in your head. No reason why you should have no libido with normal ranges
 
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If your hormones levels are what you posted them at then YES, it’s in your head. No reason why you should have no libido with normal ranges
You're wrong. Have you ever heard of post finasteride syndrome? People take finasteride, and lose libido and develop ED persistently. Their hormone levels are often normal yet symptoms persist.
 
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You're wrong. Have you ever heard of post finasteride syndrome? People take finasteride, and lose libido and develop ED persistently. Their hormone levels are often normal yet symptoms persist.
I ate arimstane for 7 months straight 150mg a day and my dick is rock solid everyday still
 
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I ate arimstane for 7 months straight 150mg a day and my dick is rock solid everyday still
Compounds effect everyone differently. Lucky for you and your magic johnson, you didn't get what I got. People have posted on here in regards to libido loss and arimistane, however.
 
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Compounds effect everyone differently. Lucky for you and your magic johnson, you didn't get what I got. People have posted on here in regards to libido loss and arimistane, however.
I think you should take some dim for a long period of time, maybe think about running a compound like amortizes slightly but keep the estrogen in control. Try to shock your e levels and hormones to work again.
 
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I think you should take some dim for a long period of time, maybe think about running a compound like amortizes slightly but keep the estrogen in control. Try to shock your e levels and hormones to work again.
Okay! Thank you for the advice. I'll mull it over in my head. If anyone else can also input their two cents or broscience, I would greatly appreciate it. I'm freaking out.
 
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Okay! Thank you for the advice. I'll mull it over in my head. If anyone else can also input their two cents or broscience, I would greatly appreciate it. I'm freaking out.
I mean it might not be the best idea but that’s my advice if you don’t have any other ideas.
 
rowz4broz

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jeeze i have honestly no idea what could be wrong.

but i will tell you this i ran a ralox + exem a couple weeks ago to try to combat some prepubertal gyno.. while i didnt notice much in the gyno deparment something special happened with my libido. was always chasing my girlfriend around. rock ****ing hard as well
 
The_Old_Guy

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1. Arimistane is named that because some supplement companies like to make OTC stuff sound like drugs.
2. Anecdotal reports that include blood test results, rarely show a lowering of E2 with any practical effect when taking it.
3. I'm no chemist/endo/oncologist - but I'm not seeing Exemestane interfering with 5-alpha reductase - and Arimistane ain't Exemestane anyway.
4. Caber has a lot of side effects:

Dostinex (cabergoline) is a dopamine receptor antagonist used to treat a hormone imbalance in which there is too much prolactin in the blood (also called hyperprolactinemia). Common side effects of Dostinex include:

nausea,
vomiting,
stomach upset or pain,
indigestion,
constipation,
gas,
dizziness,
spinning sensation,
lightheadedness,
drowsiness,
nervousness,
tiredness,
headache,
depressed mood,
hot flashes,
numbness or tingly feeling, or
dry mouth.

Tell your doctor if you experience rare but serious side effects of Dostinex including:

shortness of breath,
persistent cough,
swelling ankles or feet,
unusual tiredness,
mental/mood changes (such as nervousness),
unusual strong urges (such as increased gambling, increased sexual urges),
vision changes,
5. Stop the Caber?:

The normal range for prolactin in your blood are: Males: 2 to 18 nanograms per milliliter (ng/mL)
Did a Doctor Rx you the Caber?
 
TheMovement

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Honestly sounds stress related. I 2nd the mental conclusion. Are you sleeping enough? How’s work been? Has the budget balanced out back in your favor? These are all things that if you overstress will eat you alive.
 
The_Old_Guy

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Are your prolactin levels back to normal?
His Prolactin *was* normal according to that ^ lab range I posted. No idea if his lab was different. Low Prolactin ain't no fun either. I'd love to hear if he had a Doctor Rx Cabergoline - or if he self treated, and with what - Pharma Rx or Research Chemical?
 
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Few things don't get caught up in the suffix "tane" accutane is a commercial name for Isotretinoin or 13-cis-retinoic acid, it's related to vitamin a. Arimistane is more so related to exemestane and formestane. Now it's possible arimistane could affect 5ar, exemestane for example is structurally related to 4-androstenedione which is a substrate for both aromatase and 5ar. I've seen two studies say that exemestane shows no interference with 5ar but the drug was made for breast cancer in women only so 5ar insnt of there concern. Formestane does have studied showing 5ar reduction but this could be because it converts to 4-hydroxytestosterone which is a 5ar inhibitor.
 
cheftepesh1

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I would speak to a specialist. This could be related to other things other than the supp. Best to see what more tests show than take shots in the dark.
 
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Lol at the curved johnson. Look at it this way, if its curving the right way you will be more likely to hit her G spot!
 
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Yes, a doctor Rxed me the Caber. I've only been on the caber for the past month and I'm stopping so it was not the cabergoline.
 
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No.

Consider adding a supp containing Anacyclus pyrethrum such as Anabeta Elite or Test1fy.

Are your prolactin levels back to normal?
Can you give me your experiences with those supplements of Anacyclus? What did you notice as a result of taking it?
 
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Few things don't get caught up in the suffix "tane" accutane is a commercial name for Isotretinoin or 13-cis-retinoic acid, it's related to vitamin a. Arimistane is more so related to exemestane and formestane. Now it's possible arimistane could affect 5ar, exemestane for example is structurally related to 4-androstenedione which is a substrate for both aromatase and 5ar. I've seen two studies say that exemestane shows no interference with 5ar but the drug was made for breast cancer in women only so 5ar insnt of there concern. Formestane does have studied showing 5ar reduction but this could be because it converts to 4-hydroxytestosterone which is a 5ar inhibitor.
I made a mental connection there that was wrong. Thanks for clearing it up. Yeah, I've seen a few studies saying that exemestane can bind the 5ar receptor and that isn't necessarily a good thing. DHT plays a pivotal role in health and wellbeing.
 
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jeeze i have honestly no idea what could be wrong.

but i will tell you this i ran a ralox + exem a couple weeks ago to try to combat some prepubertal gyno.. while i didnt notice much in the gyno deparment something special happened with my libido. was always chasing my girlfriend around. rock ****ing hard as well
Interesting. I hope your girlfriend has recovered and that your gyno gets better.
 
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Lol at the curved johnson. Look at it this way, if its curving the right way you will be more likely to hit her G spot!
This newfound ability of my mine is amazing... I just need to find a woman first lol
 
TheNietzsche

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Can you give me your experiences with those supplements of Anacyclus? What did you notice as a result of taking it?
I had a similar set of effects as you from, I think, a supp a few years ago. I think it was divanil but I was on several things. Either way, I took the original Anabeta (the discontinued one with just anacyclus) and it seemed to resolve the issue. I was taking it for mass building not for this purpose. Whether it would have resolved itself without Anabeta, I can't be sure.

One study that I'm aware of demonstrated increases in LH with anacyclus (1). This mechanism may or may not be useful for you, as we don't know the cause for your symptoms.

This is only an anecdote of course. I'd agree with others to make sure all medical possibilities were covered. I'm assuming estradiol, free/total T, etc were covered.

(1) Sharma, V., Boonen, J., Spiegeleer, B. D., & Dixit, V. K. (2013). Androgenic and Spermatogenic Activity of Alkylamide‐Rich Ethanol Solution Extract of Anacyclus pyrethrum DC. Phytotherapy Research, 27(1), 99-106.
 
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His Prolactin *was* normal according to that ^ lab range I posted. No idea if his lab was different. Low Prolactin ain't no fun either. I'd love to hear if he had a Doctor Rx Cabergoline - or if he self treated, and with what - Pharma Rx or Research Chemical?
The prolactin range on my test was 0-15, and my level was at 16. Barely elevated, but granted my symptoms, the doctor thought I could benefit from a month long treatment of .25 mg/ 2x a week of cabergoline. It might've given me more energy, but nothing else to write home about really. I've tried searching low prolactin problems and can't seem to find any. Do you know of any issues with low prolactin?
 
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I had a similar set of effects as you from, I think, a supp a few years ago. I think it was divanil but I was on several things. Either way, I took the original Anabeta (the discontinued one with just anacyclus) and it seemed to resolve the issue. I was taking it for mass building not for this purpose. Whether it would have resolved itself without Anabeta, I can't be sure.

One study that I'm aware of demonstrated increases in LH with anacyclus (1). This mechanism may or may not be useful for you, as we don't know the cause for your symptoms.

This is only an anecdote of course. I'd agree with others to make sure all medical possibilities were covered. I'm assuming estradiol, free/total T, etc were covered.

(1) Sharma, V., Boonen, J., Spiegeleer, B. D., & Dixit, V. K. (2013). Androgenic and Spermatogenic Activity of Alkylamide‐Rich Ethanol Solution Extract of Anacyclus pyrethrum DC. Phytotherapy Research, 27(1), 99-106.
Thank you for you providing me with your anecdote! Hearing people get better gives me hope. It's just crazy to me that 14 pills have destroyed me mentally and physically for so long.

I'll look into a product with the anacyclus in it. I have a feeling that somewhere out there, there is something that'll make me feel better. Whether that product is time, an herb, or medication is unknown to me... but I can't give up.
 
TheNietzsche

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I've tried searching low prolactin problems and can't seem to find any. Do you know of any issues with low prolactin?
VERY low prolactin in men has been shown in a small handful of studies to have some negative effects. I'd be shocked if that's your issue, though. This is not at all a common issue. Also it seems like you developed the symptoms before you started the caber anyways.

All the studies I'm aware of on the topic of low PRL in men, of which there aren't many, were in older men, e.g.:

Corona et al. Low prolactin is associated with sexual dysfunction and psychological or metabolic disturbances in middle‐aged and elderly men: The European Male Aging Study (EMAS). The journal of sexual medicine, 11(1), pp.240-253.
 
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The_Old_Guy

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The prolactin range on my test was 0-15, and my level was at 16. Barely elevated, but granted my symptoms, the doctor thought I could benefit from a month long treatment of .25 mg/ 2x a week of cabergoline. It might've given me more energy, but nothing else to write home about really. I've tried searching low prolactin problems and can't seem to find any. Do you know of any issues with low prolactin?
The guy above found what I was thinking of. Your lab had a lower max normal - which is what I was curious about. What is your PRL now, after using the drug? Glad to see it was Dr. supervised, couldn't tell by the post.
 
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If your current bloods are normal, then this is most likely stress, which is the biggest cause of ED by far.
Try some ksm-66, make sure you are getting 7-8 hours sleep a night and if necessary get some Cialis until you get your confidence back.
 
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If your current bloods are normal, then this is most likely stress, which is the biggest cause of ED by far.
Try some ksm-66, make sure you are getting 7-8 hours sleep a night and if necessary get some Cialis until you get your confidence back.
I'm entertaining the possibility of it being stress related. But as far as I know, stress doesn't kill morning wood, does it? I have only jerked off like once in the last 12 days. I don't feel much libido and spontaneous erections are extremely rare.
 
TheNietzsche

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I'm entertaining the possibility of it being stress related. But as far as I know, stress doesn't kill morning wood, does it? I have only jerked off like once in the last 12 days. I don't feel much libido and spontaneous erections are extremely rare.
Could very well be a reaction to stress. These issues themselves are clearly stressing you out, which can be fueling the fire. And when you expect symptoms to occur they are more likely to occur (similar to a placebo effect). But for 7 months...
 
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Could very well be a reaction to stress. These issues themselves are clearly stressing you out, which can be fueling the fire. And when you expect symptoms to occur they are more likely to occur (similar to a placebo effect). But for 7 months...
I'll try and stay off of forums and see what happens. I just feel like I have too many symptoms that are strange for it to be stress induced. Frequent urination, fatigue, tight balls...

When I quit the arimistane, I was dead. No energy. I couldn't work. I even threw up after eating one time. It felt like a flu with a side of erectile dysfunction. Fun times
 
TheNietzsche

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I'll try and stay off of forums and see what happens. I just feel like I have too many symptoms that are strange for it to be stress induced. Frequent urination, fatigue, tight balls...

When I quit the arimistane, I was dead. No energy. I couldn't work. I even threw up after eating one time. It felt like a flu with a side of erectile dysfunction. Fun times
Frequent urination and fatigue could be caused by a number of things. So could tight balls, I'd suppose. In addition to stressing less (meditation may help, the above poster's advice to try KSM-66 not bad either... the best form of ashwagandha, an adaptogen). I'd see another doctor making sure not to leave out any symptoms.
 
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Ksm-66 prevents the rise in cortisol with chronic stress, it doesn't reduce baseline cortisol levels.

The feel good effect, relaxation and slight increase in testosterone may also benefit.
 
Conagher

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My experience with dopamine agonists is that is a road better left untraveled.
DA's have very troublesome side effects that last for a long time after discontinuation.
 
Conagher

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Stress can very much destroy libido,including morning wood.
Gabapentin has helped me a lot to regain sexual desire.
 
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Some websites say it inhibits cortisol formation, and cortisol is the get up, and go, motivation, stress, and energy hormone. The endocrine system maintains tight homeostatic control of itself, and tampering with this can cause huge problems. Do a cortisol saliva/blood/urine test if you haven't already done one. That can be supplemented if it is low but hopefully the body would start making it again.
I thought the problem was cortisol/adrenal related, too! But I checked my cortisol through blood and saliva and both came out normal. Along with angiotensin and ACTH. I'll do another cortisol check though to see if anything is wrong with it.
 
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Frequent urination and fatigue could be caused by a number of things. So could tight balls, I'd suppose. In addition to stressing less (meditation may help, the above poster's advice to try KSM-66 not bad either... the best form of ashwagandha, an adaptogen). I'd see another doctor making sure not to leave out any symptoms.
I've been taking ashwagandha and it's definitely helped me chill out a little. It's honestly really hard to relax when these symptoms stay on your mind, you know? But thank you. I just meditated with some candles and it felt nice to breathe :)
 
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Stress can very much destroy libido,including morning wood.
Gabapentin has helped me a lot to regain sexual desire.
Hi Conagher! I'll try that stuff out. Did you have any sides as a result of it? Any withdrawal effects? Dopamine agonists are scary. They're used by people with Parkinson's in high doses and I noticed tremors at my fingertips at a low dose of .25 mgs twice a week. I'm off now, and thankfully I have no side effects as a result of the medication.
 
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Maybe find a urologist
That's a good idea. They may be able to look at this from a different point of view and find something hormone specialists cannot. I'm a poor student in optometry school and get insurance through the state. Let's hope they have a soft spot in their hearts for soft boners.
 
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Join a yoga class, not only will you de-stress, you will suddenly find you libido goes through the roof
 

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