Fucoxanthin ups UCP1 in WAT

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    Fucoxanthin ups UCP1 in WAT


    Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.

    Maeda H, Hosokawa M, Sashima T, Funayama K, Miya****a K.

    Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.

    Mitochondrial uncoupling protein 1 (UCP1) is usually expressed only in brown adipose tissue (BAT) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. However, there is little BAT in adult humans. Therefore, UCP1 expression in tissues other than BAT is expected to reduce abdominal fat. Here, we show reduction of abdominal white adipose tissue (WAT) weights in rats and mice by feeding lipids from edible seaweed, Undaria pinnatifida. Clear signals of UCP1 protein and mRNA were detected in WAT of mice fed the Undaria lipids, although there is little expression of UCP1 in WAT of mice fed control diet. The Undaria lipids mainly consisted of glycolipids and seaweed carotenoid, fucoxanthin. In the fucoxanthin-fed mice, WAT weight significantly decreased and UCP1 was clearly expressed in the WAT, while there was no difference in WAT weight and little expression of UCP1 in the glycolipids-fed mice. This result indicates that fucoxanthin upregulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight.

    PMID: 15896707 [PubMed - as supplied by publisher]

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    Bump. Anyone source this yet?
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    I believe Dsade said he found a source and is working on gettin a small batch.
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    Quote Originally Posted by riseboi View Post
    I believe Dsade said he found a source and is working on gettin a small batch.
    Ive used it a few times before. I used the brand my store carries(seathin) and I double dosed it. It seemed to give a good 'leaning' effect, but its not very cost effective with the national brands. If DSADE brings it in, Ill definately use it when Im cutting.
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    Going to bring in a kilo fo this.

    I have a product in mind, but we will offer bulk through NP initially.

    We need dosage protocols...anyone?
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    Fucothin by Garden of Life is a mainstream product that uses that theory and that herbal compound to get the so called desired results. Of course, this program needs to be followed with a change of eating habits, however, most of the results seem to be successful. I currently sell nutritional supplements at a local health food store and Fucothin is by far one of our biggest sellers. However, I noticed that most customers usually see the best results after 21 days or so of taking the product. Good luck with the research and keep posting.

    Product: Fucothin
    Company: Garden of Life
    Price: 29.99
    Quantity: 90 softgels

    Product info: Serving Size 1 softgel
    -Proprietary Fucothin blend 200mg
    -Brown Seaweed (Undaria pinnatifida,Laminaria japonica)
    Concentrate (contains 5mg of fucoxanthin), Pomegranate
    Seed Oil

    Hopefully, this is somewhat useful information

    -Have fun fellas
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    If this is true, and effective, dosage...then you will love the price we got.

    SHould run around $1.25 a gram at a 40% extract, I believe.
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    Quote Originally Posted by dsade View Post
    If this is true, and effective, dosage...then you will love the price we got.

    SHould run around $1.25 a gram at a 40% extract, I believe.
    Bring it on! I luv it when you talk like that!!!!!!!!
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    Hell yea D. Sounds great!
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    I stopped by my local VS and decided to pick up a bottle of the fucothin. I'm wondering what type of "effects" someone would be on the lookout for while dosing. Any ideas?
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    Seeing as it is Mitochondrial uncoupler. I would suspect that you will get hot and sweaty as a result of taking this. Obviously this is not as strong as DNP, but the method of action remains the same and I would suspect that the sides would be similar.
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