- 03-17-2005, 12:28 PM
got my phosphophatidylcholine today (30mL 100mg/mL) from TLR. Problem is it is not really liquid, it is like jello (not a solid). I can't find what to dilute it with, and what concetration i need to make it. Anyone use this before or have an idea. It's gonna be hell to get out of that vial i bet.
- 03-18-2005, 12:43 AM
03-18-2005, 05:38 PM
all you got is 3000 mgs of the stuff? that is like a 2-3 day supply. how much did you pay for it?
it is supposed to be a mood enhancer and cortisol suppressant. it is just a form of choline.
Last edited by hogiejoe; 03-18-2005 at 10:19 PM.
03-18-2005, 07:02 PM
Well, I'm not sure if he spelled it wrong or what, but I was thinking it was just lecithin, which swells in water to form a suspension.
03-18-2005, 08:00 PM
Lipostabil.... this is meant to be injected. And a little goes a long way. And I'd ask instynct if you can dilute it but I'm pretty sure you cant use water.
03-18-2005, 10:20 PM
are you trying to inject this stuff? now that i read your post over i am not sure you know what exactly it is that you have.
03-18-2005, 10:25 PM
i went to their website and i could not even find that. and some of the prices on the site are freaking ridiculous.
03-19-2005, 09:49 AM
Don't be stupid guys! I don't know what he's charging, but I can go to Walmart and buyfor 10$ per 32oz! The thick liquid is just as pure as the sticky solid. If the solid is white it's actually purer, but if the solid is yellow or brown, you may as well get some liquid and micron filter if you plan to inject. It's lipotropic so I assume you mean spot injections to mobilize local fat in specific areas or something?
Last edited by DR.D; 03-19-2005 at 12:31 PM.
03-19-2005, 10:05 AM
Here are some link with info and before and after pictures http://www.findarticles.com/p/articl...2/ai_110220257
03-19-2005, 10:07 AM
There is a difference between lechtin and the phosphophatidylcholine used in lipodissolve. It has something to do with the number or chains and carbon rings i think, as well as they come from different plants. Only one type rom one plant works for this I beleive.Originally Posted by DR.D
03-19-2005, 02:20 PM
Good links, but I'm having trouble finding the ingredients of Lipostabil, just that it 250mg/ml PC, but what the other 750mg are, who knows! How were you going to formulate this stuff?
03-19-2005, 11:04 PM
03-20-2005, 11:56 AM
PC is the only active ingrediant, the rest is the solvent. and there is not always 1g/ml in any solution FYI
03-20-2005, 01:48 PM
Yes, you are correct. I was just trying to make a point. In fact, I'm sure ingredient #2 is DI H2O or isotonic saline, and since PC swells in water, I'm sure the specific gravity will not be 1.0, however, you'd have to be insane to discount the inacitives as unimportant and just shoot it in some water as an untreated, aqueous suspension. If you get the rest of the components (should be 5 or 6 I'd think) I'll help you formulate a sterile, effective mixture. You may wanna ask dego, I think he has some experience with this too.Originally Posted by TheGame46
03-20-2005, 08:39 PM
03-20-2005, 09:44 PM
03-20-2005, 09:54 PM
03-20-2005, 10:17 PM
The solution you get from TLR is formula ready sterile and ready to use. the conc. is 100mg/ml. Pc would not be soluble in water i think it needs an organic solvent or ionic solutoin.Originally Posted by DR.D
03-20-2005, 10:22 PM
this thread started as a question I had but more people responded to this one. I was keeping the original log on anabolex but they are just flamming me for even trying the product. People here seem more optamistic and at least repect the fact that I'm taking the time to log the results.Originally Posted by Beowulf
03-20-2005, 10:54 PM
I hear you bro. Maybe you should post a link to the other...duh, I just did, and leave a note for anyone curious to go to the other thread. Just a thought.
03-21-2005, 12:36 AM
Like I said, PC swells in water to form a thick, aqueous suspension. Was it at all turbid? I saw your pics, I was not surprised as edema and bruising are common up to weeks after. They suggest compression to help. So how did you dilute this "jello" or did you use as is?Originally Posted by TheGame46
03-21-2005, 12:41 AM
i know this actually kills the adipose cells and not just reduce their size, but damn; i'll stick with clen/ECA
03-21-2005, 12:50 AM
Yeah, I'd rather just lift my ass off and take drugs too! But I was interested at first because it forces the fat out by emulsifying it and making it water soluble. May still be an idea for stubborn fatty areas if I ever get that obsessed again. As for now, my 16% bf ass really don't care enough to shoot my abs 40x with 2mm points every two weeks 4x total. Give me the damn yo and let my skin crawl!Originally Posted by chasec
Last edited by DR.D; 03-21-2005 at 08:09 AM.
03-21-2005, 03:12 AM
03-21-2005, 08:01 AM
Just curious Game, how many forums are you going to post this perplexing log under?
And how many sites are you posting this on?
I ask because I have seen it on multiple sites and on multiple AM forums.
03-21-2005, 08:10 AM
Hey Chem, good to see you around here. He has got it mixed up pretty well on this one.Originally Posted by ChemicalD
03-21-2005, 11:23 AM
03-21-2005, 10:17 PM
To those that don't know, Chem D is an analytical chemist from Avant. Glad you made the switch! I tried to log on to Avant earlier today and they had my account all messed up. This is a great board, the guys are knowledgable and mature to one another (no ego driven flamers).Originally Posted by ChemicalD
03-21-2005, 11:34 PM
03-22-2005, 01:12 AM
surfactants+ phosphotydlecholin = cell lysis
Many results of many studies indicate that nonionic surfactants interact not only with proteins but also with membrane phospholipids by modifying their structure and permeability. As phospholipids are chemically simple compounds, the principles of various surfactant-phospholipid interactions and the character of forces involved are fairly well known.
Surfactants generally increase the permeability of phospholipid membranes and vesicles, causing leakage of compounds with low molecular mass. The loss of ions, amino acids, etc., may result in cell damage or cell death. It is generally accepted that the increased permeability is the result of membrane disruption. Supramolecular surfactants (polyethylene glycol + dicarboxylic acid esters) as well as Triton X-100 readily disrupt egg yolk phosphatidylcholine membranes (32). An increase in permeability has been observed in many model systems: Triton X-100 and some new synthetic surfactants caused leakage from palmitoyloleoyl phosphatidylcholine/cholesterol vesicles, which are large and unilamellar (33). The concentration and aggregation state of surfactants also exert a considerable effect on their membrane-damaging capacity: monomeric Triton X-100 causes leakage of dipalmitoyl phosphatidylcholine vesicles, whereas micellar solutions result in the catastrophic rupture of membrane
well i look into transdermal delivery of lecithin, its seams that phosphtidylecholin can be delivered systematicly, and localy since its amphiphilic.
Localized and systemic drug delivery. Liposomes as drug carriers. Liposomes
have shown great potential as novel drug carriers for
dermal and transdermal systems. Liposomes are microscopic
vesicles composed of membrane-like lipid layers surrounding
an aqueous compartment (23). Phospholipids most often are
used in the preparation of liposomes. Because of the amphiphilic
nature of phospholipids, when they are dispersed in aqueous
solutions they arrange in bilayers, with the fatty-acid tails
(nonpolar) located in the membrane’s interior and the polar
heads pointing outward. One of the advantages of using liposomes
as drug carriers is that both lipophilic as well as hydrophilic
drugs can be incorporated within the lipid bilayers and
aqueous compartment, respectively. They also serve as a reservoir
for the prolonged release of drugs within various skin
layers (23–28), thereby reducing the rapid elimination of drug
into the blood or lymphatic circulation (29). This quality makes
the liposome delivery system useful for treating various skin
disorders. Because they are nongreasy and nontacky, liposomal
preparations are cosmetically acceptable.
Various mechanisms have been proposed for the delivery of
drugs through the skin using liposomes as a drug carrier. In
these systems, liposomes carry a drug in dissolved form to the
skin surface, and their lipid bilayer ruptures as a result !!!!!!
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