Phosphophatidylcholine - AnabolicMinds.com

Phosphophatidylcholine

  1. New Member
    TheGame46's Avatar
    Join Date
    Jan 2005
    Posts
    223
    Rep Power
    229

    Reputation

    Phosphophatidylcholine


    got my phosphophatidylcholine today (30mL 100mg/mL) from TLR. Problem is it is not really liquid, it is like jello (not a solid). I can't find what to dilute it with, and what concetration i need to make it. Anyone use this before or have an idea. It's gonna be hell to get out of that vial i bet.
    Thanks

  2. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by TheGame46
    got my phosphophatidylcholine today (30mL 100mg/mL) from TLR. Problem is it is not really liquid, it is like jello (not a solid). I can't find what to dilute it with, and what concetration i need to make it. Anyone use this before or have an idea. It's gonna be hell to get out of that vial i bet.
    Thanks
    What are people using this for and how is it being administered?
  3. Banned
    hogiejoe's Avatar
    Join Date
    Dec 2003
    Age
    32
    Posts
    250
    Rep Power
    0

    Reputation

    all you got is 3000 mgs of the stuff? that is like a 2-3 day supply. how much did you pay for it?

    it is supposed to be a mood enhancer and cortisol suppressant. it is just a form of choline.
    Last edited by hogiejoe; 03-18-2005 at 08:19 PM.
    •   
       

  4. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Well, I'm not sure if he spelled it wrong or what, but I was thinking it was just lecithin, which swells in water to form a suspension.
  5. New Member
    dego's Avatar
    Join Date
    Oct 2003
    Posts
    192
    Rep Power
    230

    Reputation

    Lipostabil.... this is meant to be injected. And a little goes a long way. And I'd ask instynct if you can dilute it but I'm pretty sure you cant use water.
  6. Banned
    hogiejoe's Avatar
    Join Date
    Dec 2003
    Age
    32
    Posts
    250
    Rep Power
    0

    Reputation

    are you trying to inject this stuff? now that i read your post over i am not sure you know what exactly it is that you have.
  7. Banned
    hogiejoe's Avatar
    Join Date
    Dec 2003
    Age
    32
    Posts
    250
    Rep Power
    0

    Reputation

    i went to their website and i could not even find that. and some of the prices on the site are freaking ridiculous.
  8. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Don't be stupid guys! I don't know what he's charging, but I can go to Walmart and buy liquid lecithin for 10$ per 32oz! The thick liquid is just as pure as the sticky solid. If the solid is white it's actually purer, but if the solid is yellow or brown, you may as well get some liquid and micron filter if you plan to inject. It's lipotropic so I assume you mean spot injections to mobilize local fat in specific areas or something?
    Last edited by DR.D; 03-19-2005 at 10:31 AM.
  9. New Member
    TheGame46's Avatar
    Join Date
    Jan 2005
    Posts
    223
    Rep Power
    229

    Reputation

    Quote Originally Posted by DR.D
    Don't be stupid guys! I don't know what he's charging, but I can go to Walmart and bye liquid lecithin for 10$ per 32oz! The thick liquid is just as pure as the sticky solid. If the solid is white it's actually purer, but if the solid is yellow or brown, you may as well get some liquid and micron filter if you plan to inject. It's lipotropic so I assume you mean spot injections to mobilize local fat in specific areas or something?
    There is a difference between lechtin and the phosphophatidylcholine used in lipodissolve. It has something to do with the number or chains and carbon rings i think, as well as they come from different plants. Only one type rom one plant works for this I beleive.
  10. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Good links, but I'm having trouble finding the ingredients of Lipostabil, just that it 250mg/ml PC, but what the other 750mg are, who knows! How were you going to formulate this stuff?
  11. Banned
    biggjohn's Avatar
    Join Date
    Mar 2004
    Posts
    180
    Rep Power
    0

    Reputation

    Quote Originally Posted by DR.D
    Don't be stupid guys! I don't know what he's charging, but I can go to Walmart and buy liquid lecithin for 10$ per 32oz! The thick liquid is just as pure as the sticky solid. If the solid is white it's actually purer, but if the solid is yellow or brown, you may as well get some liquid and micron filter if you plan to inject. It's lipotropic so I assume you mean spot injections to mobilize local fat in specific areas or something?
    16 oz for $2.50 at my local grocery store (Wegman's)
  12. New Member
    TheGame46's Avatar
    Join Date
    Jan 2005
    Posts
    223
    Rep Power
    229

    Reputation

    PC is the only active ingrediant, the rest is the solvent. and there is not always 1g/ml in any solution FYI
  13. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by TheGame46
    PC is the only active ingrediant, the rest is the solvent. and there is not always 1g/ml in any solution FYI
    Yes, you are correct. I was just trying to make a point. In fact, I'm sure ingredient #2 is DI H2O or isotonic saline, and since PC swells in water, I'm sure the specific gravity will not be 1.0, however, you'd have to be insane to discount the inacitives as unimportant and just shoot it in some water as an untreated, aqueous suspension. If you get the rest of the components (should be 5 or 6 I'd think) I'll help you formulate a sterile, effective mixture. You may wanna ask dego, I think he has some experience with this too.
  14. Pityin' fools since '81
    chasec's Avatar
    Join Date
    Dec 2003
    Age
    32
    Posts
    1,220
    Rep Power
    742

    Reputation

    check out the pics he posted in his log; looks very, very, painful
  15. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by chasec
    check out the pics he posted in his log; looks very, very, painful
    Isn't this his log? I can't find them in the cycles or pics forum
  16. Registered User
    Beowulf's Avatar
    Join Date
    Dec 2004
    Age
    36
    Posts
    3,430
    Rep Power
    2150

    Reputation

    This is the log. He has 2 or 3 logs on this topic. Confusing.
    my phosphophatidylcholine log w/pics
  17. New Member
    TheGame46's Avatar
    Join Date
    Jan 2005
    Posts
    223
    Rep Power
    229

    Reputation

    Quote Originally Posted by DR.D
    Yes, you are correct. I was just trying to make a point. In fact, I'm sure ingredient #2 is DI H2O or isotonic saline, and since PC swells in water, I'm sure the specific gravity will not be 1.0, however, you'd have to be insane to discount the inacitives as unimportant and just shoot it in some water as an untreated, aqueous suspension. If you get the rest of the components (should be 5 or 6 I'd think) I'll help you formulate a sterile, effective mixture. You may wanna ask dego, I think he has some experience with this too.
    The solution you get from TLR is formula ready sterile and ready to use. the conc. is 100mg/ml. Pc would not be soluble in water i think it needs an organic solvent or ionic solutoin.
  18. New Member
    TheGame46's Avatar
    Join Date
    Jan 2005
    Posts
    223
    Rep Power
    229

    Reputation

    Quote Originally Posted by Beowulf
    This is the log. He has 2 or 3 logs on this topic. Confusing.
    my phosphophatidylcholine log w/pics
    this thread started as a question I had but more people responded to this one. I was keeping the original log on anabolex but they are just flamming me for even trying the product. People here seem more optamistic and at least repect the fact that I'm taking the time to log the results.
  19. Registered User
    Beowulf's Avatar
    Join Date
    Dec 2004
    Age
    36
    Posts
    3,430
    Rep Power
    2150

    Reputation

    I hear you bro. Maybe you should post a link to the other...duh, I just did, and leave a note for anyone curious to go to the other thread. Just a thought.
  20. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by TheGame46
    got my phosphophatidylcholine today (30mL 100mg/mL) from TLR. Problem is it is not really liquid, it is like jello (not a solid). I can't find what to dilute it with, and what concetration i need to make it. Anyone use this before or have an idea. It's gonna be hell to get out of that vial i bet.
    Thanks
    Like I said, PC swells in water to form a thick, aqueous suspension. Was it at all turbid? I saw your pics, I was not surprised as edema and bruising are common up to weeks after. They suggest compression to help. So how did you dilute this "jello" or did you use as is?
  21. Pityin' fools since '81
    chasec's Avatar
    Join Date
    Dec 2003
    Age
    32
    Posts
    1,220
    Rep Power
    742

    Reputation

    i know this actually kills the adipose cells and not just reduce their size, but damn; i'll stick with clen/ECA
  22. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by chasec
    i know this actually kills the adipose cells and not just reduce their size, but damn; i'll stick with clen/ECA
    Yeah, I'd rather just lift my ass off and take drugs too! But I was interested at first because it forces the fat out by emulsifying it and making it water soluble. May still be an idea for stubborn fatty areas if I ever get that obsessed again. As for now, my 16% bf ass really don't care enough to shoot my abs 40x with 2mm points every two weeks 4x total. Give me the damn yo and let my skin crawl!
    Last edited by DR.D; 03-21-2005 at 06:09 AM.
  23. Advanced Member
    x_muscle's Avatar
    Join Date
    Oct 2003
    Posts
    639
    Rep Power
    85477

    Reputation Reputation

    this was discussed here before many times:
    finaly study on Lipostabil
  24. Have you seen my stapler???
    ChemicalD's Avatar
    Join Date
    Feb 2005
    Posts
    196
    Rep Power
    215

    Reputation

    Just curious Game, how many forums are you going to post this perplexing log under?

    And how many sites are you posting this on?

    I ask because I have seen it on multiple sites and on multiple AM forums.

  25. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by ChemicalD
    Just curious Game, how many forums are you going to post this perplexing log under?

    And how many sites are you posting this on?

    I ask because I have seen it on multiple sites and on multiple AM forums.

    Hey Chem, good to see you around here. He has got it mixed up pretty well on this one.
  26. Have you seen my stapler???
    ChemicalD's Avatar
    Join Date
    Feb 2005
    Posts
    196
    Rep Power
    215

    Reputation

    Quote Originally Posted by DR.D
    Hey Chem, good to see you around here.
    Same to you buddy. This is my new home.
  27. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by ChemicalD
    Same to you buddy. This is my new home.
    To those that don't know, Chem D is an analytical chemist from Avant. Glad you made the switch! I tried to log on to Avant earlier today and they had my account all messed up. This is a great board, the guys are knowledgable and mature to one another (no ego driven flamers).
  28. Pityin' fools since '81
    chasec's Avatar
    Join Date
    Dec 2003
    Age
    32
    Posts
    1,220
    Rep Power
    742

    Reputation

    well, welcome!
  29. New Member
    mass_builder's Avatar
    Join Date
    Nov 2003
    Posts
    294
    Rep Power
    280

    Reputation

    surfactants+ phosphotydlecholin = cell lysis

    Many results of many studies indicate that nonionic surfactants interact not only with proteins but also with membrane phospholipids by modifying their structure and permeability. As phospholipids are chemically simple compounds, the principles of various surfactant-phospholipid interactions and the character of forces involved are fairly well known.


    Surfactants generally increase the permeability of phospholipid membranes and vesicles, causing leakage of compounds with low molecular mass. The loss of ions, amino acids, etc., may result in cell damage or cell death. It is generally accepted that the increased permeability is the result of membrane disruption. Supramolecular surfactants (polyethylene glycol + dicarboxylic acid esters) as well as Triton X-100 readily disrupt egg yolk phosphatidylcholine membranes (32). An increase in permeability has been observed in many model systems: Triton X-100 and some new synthetic surfactants caused leakage from palmitoyloleoyl phosphatidylcholine/cholesterol vesicles, which are large and unilamellar (33). The concentration and aggregation state of surfactants also exert a considerable effect on their membrane-damaging capacity: monomeric Triton X-100 causes leakage of dipalmitoyl phosphatidylcholine vesicles, whereas micellar solutions result in the catastrophic rupture of membrane

    well i look into transdermal delivery of lecithin, its seams that phosphtidylecholin can be delivered systematicly, and localy since its amphiphilic.



    Localized and systemic drug delivery. Liposomes as drug carriers. Liposomes
    have shown great potential as novel drug carriers for
    dermal and transdermal systems. Liposomes are microscopic
    vesicles composed of membrane-like lipid layers surrounding
    an aqueous compartment (23). Phospholipids most often are
    used in the preparation of liposomes. Because of the amphiphilic
    nature of phospholipids, when they are dispersed in aqueous
    solutions they arrange in bilayers, with the fatty-acid tails
    (nonpolar) located in the membrane’s interior and the polar
    heads pointing outward. One of the advantages of using liposomes
    as drug carriers is that both lipophilic as well as hydrophilic
    drugs can be incorporated within the lipid bilayers and
    aqueous compartment, respectively. They also serve as a reservoir
    for the prolonged release of drugs within various skin
    layers (23–28), thereby reducing the rapid elimination of drug
    into the blood or lymphatic circulation (29). This quality makes
    the liposome delivery system useful for treating various skin
    disorders. Because they are nongreasy and nontacky, liposomal
    preparations are cosmetically acceptable.
    Various mechanisms have been proposed for the delivery of
    drugs through the skin using liposomes as a drug carrier. In
    these systems, liposomes carry a drug in dissolved form to the
    skin surface, and their lipid bilayer ruptures as a result !!!!!!

    http://ptech.adv100.com/pharmtech/d...404/article.pdf
  30. Have you seen my stapler???
    ChemicalD's Avatar
    Join Date
    Feb 2005
    Posts
    196
    Rep Power
    215

    Reputation

    chasec, Dr. D.

    Thanks for the welcome.

    We all have to do our parts to keep brotelligence in check.

    And this is a wonderful board, not to say that Avant isn't.

  31. Elite Member
    DR.D's Avatar
    Stats
    6'0"  228 lbs.
    Join Date
    Dec 2003
    Posts
    6,779
    Rep Power
    307852

    Reputation Reputation Reputation Reputation Reputation Reputation Reputation

    Quote Originally Posted by mass_builder
    surfactants+ phosphotydlecholin = cell lysis

    Many results of many studies indicate that nonionic surfactants interact not only with proteins but also with membrane phospholipids by modifying their structure and permeability. As phospholipids are chemically simple compounds, the principles of various surfactant-phospholipid interactions and the character of forces involved are fairly well known.


    Surfactants generally increase the permeability of phospholipid membranes and vesicles, causing leakage of compounds with low molecular mass. The loss of ions, amino acids, etc., may result in cell damage or cell death. It is generally accepted that the increased permeability is the result of membrane disruption. Supramolecular surfactants (polyethylene glycol + dicarboxylic acid esters) as well as Triton X-100 readily disrupt egg yolk phosphatidylcholine membranes (32). An increase in permeability has been observed in many model systems: Triton X-100 and some new synthetic surfactants caused leakage from palmitoyloleoyl phosphatidylcholine/cholesterol vesicles, which are large and unilamellar (33). The concentration and aggregation state of surfactants also exert a considerable effect on their membrane-damaging capacity: monomeric Triton X-100 causes leakage of dipalmitoyl phosphatidylcholine vesicles, whereas micellar solutions result in the catastrophic rupture of membrane

    well i look into transdermal delivery of lecithin, its seams that phosphtidylecholin can be delivered systematicly, and localy since its amphiphilic.



    Localized and systemic drug delivery. Liposomes as drug carriers. Liposomes
    have shown great potential as novel drug carriers for
    dermal and transdermal systems. Liposomes are microscopic
    vesicles composed of membrane-like lipid layers surrounding
    an aqueous compartment (23). Phospholipids most often are
    used in the preparation of liposomes. Because of the amphiphilic
    nature of phospholipids, when they are dispersed in aqueous
    solutions they arrange in bilayers, with the fatty-acid tails
    (nonpolar) located in the membrane’s interior and the polar
    heads pointing outward. One of the advantages of using liposomes
    as drug carriers is that both lipophilic as well as hydrophilic
    drugs can be incorporated within the lipid bilayers and
    aqueous compartment, respectively. They also serve as a reservoir
    for the prolonged release of drugs within various skin
    layers (23–28), thereby reducing the rapid elimination of drug
    into the blood or lymphatic circulation (29). This quality makes
    the liposome delivery system useful for treating various skin
    disorders. Because they are nongreasy and nontacky, liposomal
    preparations are cosmetically acceptable.
    Various mechanisms have been proposed for the delivery of
    drugs through the skin using liposomes as a drug carrier. In
    these systems, liposomes carry a drug in dissolved form to the
    skin surface, and their lipid bilayer ruptures as a result !!!!!!

    http://ptech.adv100.com/pharmtech/d...404/article.pdf
    Some great info, now do you know the proprietary ingredients in Limpo?
  32. Registered User
    ericnb_98's Avatar
    Join Date
    Dec 2004
    Age
    51
    Posts
    136
    Rep Power
    188

    Reputation

    Bump, This conversation just kinda fell off, Did you delute it with any thing, how is it now? I heard you need about four treatments to
    scuplt certain areas.
  33. Anabolic Innovations Owner
    CROWLER's Avatar
    Join Date
    Dec 2002
    Posts
    6,545
    Rep Power
    4828

    Reputation

    Quote Originally Posted by DR.D
    Some great info, now do you know the proprietary ingredients in Limpo?
    WHat are they?
  34. New Member
    die2live's Avatar
    Join Date
    May 2005
    Age
    54
    Posts
    5
    Rep Power
    116

    Reputation

    If someone could PM me with info about PC from TLR I would appreciate it.

    Thanks
  35. New Member
    biketuna's Avatar
    Join Date
    May 2003
    Age
    46
    Posts
    41
    Rep Power
    159

    Reputation

    I put in a hot water bath and shook it up. repeat as needed.

    It cleared it up for me.
  

  
 

Similar Forum Threads

  1. my phosphophatidylcholine log w/pics
    By TheGame46 in forum Anabolics
    Replies: 58
    Last Post: 05-19-2007, 03:17 PM
  2. Phosphophatidylcholine
    By TheGame46 in forum Anabolics
    Replies: 5
    Last Post: 11-01-2005, 07:07 PM
  3. Phosphophatidylcholine
    By TheGame46 in forum Anabolics
    Replies: 9
    Last Post: 03-19-2005, 08:58 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in