nutrient timing with regard to DopaDex (L-Dopa)

[JudoJosh]

Effect of glucose on the growth hormone response to L-dopa in normal and diabetic subjects.

Abstract

The effect of hyperglycemia on the growth hormone response to oral L-dopa (500 mg.) was assessed in eight normal and eight insulin-dependent diabetic subjects. A peak growth hormone response of 21.0 +/- 4.0 ng./ml. (mean +/- S.E.M.), significantly above baseline (p less than 0.01), was achieved in the normal group following oral L-dopa. Glucose concentrations did not change and were approximately 80 mg./100 ml. throughout. Administration of 100 gm. oral glucose with the L-dopa, or thirty minutes thereafter, totally suppressed the growth hormone response in all eight and six of the subjects, respectively. A peak growth hormone response of 20.0 "/- 1.7 ng./ml. (mean +/- S.E.M.), significantly above baseline (p less than 0.001), was obtained in eight nonobese, insulin-dependent diabetics, in spite of prevailing hyperglycemia (mean plasma glucose 243-258 mg./100 ml.) throughout the test. Endogenous hyperglycemia was achieved in these patients by lessening the usual strict adherence to plasma glucose control for the purpose of the study. These results suggest an abnormality in the hypothalamus or pituitary of diabetic subjects allowing growth hormone responsiveness in spite of hyperglycemia.

PMID: 1158029

If you are supplementing with DopaDex in hopes of increasing GH than it is advisable to avoid taking it with food or within 1 hour of DopaDex

Additional dose/use suggestions for DopaDex (L-Dopa)

Timing
• Before bed
• Before workout
• Before fasted cardio

Amount
• l-Dopa, when supplemented via Mucuna Pruriens, is more bioactive than L-dopa itself. So to achieve a Mucuna equivalent of say 500mg straight L-Dopa, you would need to take about 1/2 (250mg)

Putting it together
• Workout day - Upon waking take 1 cap DopaDex in a fasted state (avoid food for the next hour), 2 caps pre-exercise, 1-2 cap pre-bed
• On non-workout day - Upon waking take 2 caps DopaDex 30mins pre fasted cardio, 1-2 caps pre bed

Suggested Complimentary Products
• ChloroTEST(Chlorophytum borivilianum)

 

[amarula]

Good info, thanks

 

[Grayson]

How do you dose this pre-bed if ingesting casein?

 

[T-Bone]

How do you dose this pre-bed if ingesting casein?

Do people still drink casein protein before bed?.

 

[Grayson]

Do people still drink casein protein before bed?.

Cottage cheese, casein, it's all the same. Plus if I haven't hit protein macros for the day it's nice just to have a shake.

Plus by casein it could be any one of our favorite and trusted brand's protein