Ala seems to work, but maybe I just don't use enough. Vanadyl Sulfate, however, is the real deal. No doubt about it, I've used it for years. Inorganic minerals are not that toxic, very little is even absorbed. 100-150mg with a carb load after a w/o or with a good meal before bed works very impressively. Hardness and fullness that can't be denied. I've read studies involving use with diabetics and toxicity is not noted either, but it only works at these higher doses and it must be cycled 2on/2off to retain effeciveness.