Via Pubmed: Supplements have negligible effect in humans

[Colin]

I thought this was humorous.Apparently,a good handful of the well touted,staple supplements for fat loss don't do jack balls in non-obese,relatively healthy humans.


Aging (Albany NY). 2013 Sep 4. [Epub ahead of print]
[h=1]Multiple dietary supplements do not affect metabolic and cardiovascular health.[/h]Soare A, Weiss EP, Holloszy JO, Fontana L.
[h=3]Source[/h]Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63130, USA.

[h=3]Abstract[/h]Dietary supplements are widely used for health purposes. However, little is known about the metabolic and cardiovascular effects of combinations of popular over-the-counter supplements, each of which has been shown to have anti-oxidant, anti-inflammatory and pro-longevity properties in cell culture or animal studies. This study was a 6-month randomized, single-blind controlled trial, in which 56 non-obese (BMI 21.0-29.9 kg/m2) men and women, aged 38 to 55 yr, were assigned to a dietary supplement (SUP) group or control (CON) group, with a 6-month follow-up. The SUP group took 10 dietary supplements each day (100 mg of resveratrol, a complex of 800 mg each of green, black, and white tea extract, 250 mg of pomegranate extract, 650 mg of quercetin, 500 mg of acetyl-l-carnitine, 600 mg of lipoic acid, 900 mg of curcumin, 1 g of sesamin, 1.7 g of cinnamon bark extract, and 1.0 g fish oil). Both the SUP and CON groups took a daily multivitamin/mineral supplement. The main outcome measures were arterial stiffness, endothelial function, biomarkers of inflammation and oxidative stress, and cardiometabolic risk factors. Twenty-four weeks of daily supplementation with 10 dietary supplements did not affect arterial stiffness or endothelial function in nonobese individuals. These compounds also did not alter body fat measured by DEXA, blood pressure, plasma lipids, glucose, insulin, IGF-1, and markers of inflammation and oxidative stress. In summary, supplementation with a combination of popular dietary supplements has no cardiovascular or metabolic effects in non-obese relatively healthy individuals.


PMID: 24036417

 

[JudoJosh]

Would have been a better study if they used better dosages of some of them.



Plus

56 non-obese (BMI 21.0-29.9 kg/m2) men and women, aged 38 to 55 yr, were assigned to a dietary supplement (SUP) group or control (CON) group

Would suggest that they were basically already healthy to begin with. Cant say im surprised that healthy people didnt benefit from them. That like raising protein intake on a sedentary individual and expecting hypertrophy.

 

[FL3X MAGNUM]

That like raising protein intake on a sedentary individual and expecting hypertrophy.

Kind of far fetched analogy but I get where you're going lol.

 

[mw1]

Would have been a better study if they used better dosages of some of them.

.

This^^^ and they could have used some better supps~ half of those I would pass on

 

[Jiigzz]

Does it allude to what their daily intake was like? If it was ad libitum then perhaps thats your answer.