Freezing on Alpha T2

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  1. Quote Originally Posted by lronFist View Post
    Those thyroidals may cause one to become cold because they are anti thyrotrophic.

    And furthermore, a thermogenic causes one to become warm, not cold.

    If you activate the SNS with VR-type compounds then you would stimulate sweating in the absence of thermogenesis.

    This is one of the dumbest threads I've ever read.
    Never heard of cold sweats?

    A quick google search of "yohimbe cold sweats" sure does give a lot of hits...

    Not saying you were wrong, just curious if you believe that if this is physically impossible, why exactly there are sensitive users to yohimbe extracts and yohimbine HCl who get cold sweats, even from pure yohimbine and nothing else
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  2. Quote Originally Posted by mr.cooper69 View Post
    Oleuropein/olive leaf extract is but an ingredient in the formula. It wasn't included with the intention of mimicking supraphysiological levels of T4/T3. Rather, it has beneficial effects on metabolism in the murine model (the HED for increased peripheral deiodinase activity, even at ~60%, is very low), blood glucose, and the cardiovascular system.

    I'll look into the old veterinary research for sure, I'm assuming in dogs? Anecdotally, caffeine + yohimbine makes my extremeties cold, which can give the illusion of a lowered overall body temperature.
    Olive leaf is becoming very popular for multiple benefits. As we discussed before, one of the more frequently studied extracts the past 2-3 years
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  3. Quote Originally Posted by nattydisaster View Post
    Never heard of cold sweats?

    A quick google search of "yohimbe cold sweats" sure does give a lot of hits...
    It increases central SNS tone which also happens to increase sweating and subsequent evaporative cooling. Ascribing thermogenesis to feeling cold is moronic.

  4. Quote Originally Posted by nattydisaster View Post
    Olive leaf is becoming very popular for multiple benefits. As we discussed before, one of the more frequently studied extracts the past 2-3 years
    I could really care less about its "multiple benefits." This thread is about thermogenesis, of which olive leaf does not modulate.

  5. Quote Originally Posted by mr.cooper69 View Post
    the HED for increased peripheral deiodinase activity, even at ~60%, is very low

    How do you figure?
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  6. Quote Originally Posted by lronFist View Post
    How do you figure?
    http://www.ncbi.nlm.nih.gov/pubmed/12164280

    From the full text, 500 ug resulted in a ~300% increase in T3. Fed to rats at 125-150g bodyweight. About 3.33mg/kg.

    Scaling for BSA, you're looking at 37.5-50mg/day for a human male of reasonable bodyweight.
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