Agmatine? Precursor or Inhibitor?

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    Agmatine? Precursor or Inhibitor?


    Alright I've been trying to educate myself on agmatine. Does it increase NO production or inhibit it? Also would it be beneficial to take agmatine with arginine, citrulline, or ornithine?

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    Quote Originally Posted by Z28Luver7777 View Post
    Alright I've been trying to educate myself on agmatine. Does it increase NO production or inhibit it? Also would it be beneficial to take agmatine with arginine, citrulline, or ornithine?
    increases NO - arginine not so much - citrulline yes - ornithine? could not hurt imo
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    Also the Enhanced PES product has the agmatine also with nitrates for high end NO production
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    Quote Originally Posted by Z28Luver7777 View Post
    Alright I've been trying to educate myself on agmatine. Does it increase NO production or inhibit it? Also would it be beneficial to take agmatine with arginine, citrulline, or ornithine?
    Increases NO production. I would take it with CM. No need for arginine, Agmatine will replace that with much better results.
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    Agmatine would theoretically work better with nitrates than citrulline based on its action at the imidazoline receptor. Just saying
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    The above is my own opinion and does not reflect the opinion of PES
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    Quote Originally Posted by Z28Luver7777 View Post
    Alright I've been trying to educate myself on agmatine. Does it increase NO production or inhibit it? Also would it be beneficial to take agmatine with arginine, citrulline, or ornithine?
    From what I've seen it increases NO when there isn't too much but does inhibit it when there are unsafe levels. Taking it with enough citrulline should be fine, though a citrulline/norvaline/agmatine combo could be counter productive (also unnecessary imo).

    ...Still want to try Hemavol anyways.
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    Quote Originally Posted by mr.cooper69 View Post
    Agmatine would theoretically work better with nitrates than citrulline based on its action at the imidazoline receptor. Just saying
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    Quote Originally Posted by Z28Luver7777 View Post
    Alright I've been trying to educate myself on agmatine. Does it increase NO production or inhibit it? Also would it be beneficial to take agmatine with arginine, citrulline, or ornithine?
    Best not to overthink it as it isn't always as easy as a biochem flowchart. Agmatine will serve you well on its own. The others are not really needed.
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    Quote Originally Posted by Aleksandar37 View Post
    Best not to overthink it as it isn't always as easy as a biochem flowchart. Agmatine will serve you well on its own. The others are not really needed.
    I have heard much good from people taking CM as well as Nitrates with Agmatine. I will say I think a statement like "The others are not really needed" is relative, no offense to you personally.
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    Quote Originally Posted by Touey View Post
    I have heard much good from people taking CM as well as Nitrates with Agmatine. I will say I think a statement like "The others are not really needed" is relative, no offense to you personally.
    Where the **** are CM and nitrates mentioned in the post I quoted? I was talking about "arginine, citrulline, or ornithine" which is why I quoted him. This thread is about NO production.
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    Quote Originally Posted by Aleksandar37 View Post

    Best not to overthink it as it isn't always as easy as a biochem flowchart. Agmatine will serve you well on its own. The others are not really needed.
    Agreed always have nice results with just bulk agmatine
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