Creatine, yay or nay?
- 04-01-2013, 09:03 PM
- 04-01-2013, 11:53 PM
"The only good is knowledge and the only evil is ignorance." - Socrates
- 04-01-2013, 11:57 PM
This one is pretty controversial
Three weeks ofsupplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players.
This study investigated resting concentrations of selected androgens after 3 weeks of creatine supplementation in male rugby players. It was hypothesized that the ratio of dihydrotestosterone (DHT, a biologically more active androgen) to testosterone (T) would change with creatine supplementation.
Double-blind placebo-controlled crossover study with a 6-week washout period.
SETTING:Rugby Institute in South Africa.
PARTICIPANTS:College-aged rugby players (n = 20) volunteered for the study, which took place during the competitive season.
INTERVENTIONS:Subjects loaded with creatine (25 g/day creatine with 25 g/day glucose) or placebo (50 g/day glucose) for 7 days followed by 14 days of maintenance (5 g/day creatine with 25 g/day glucose or 30 g/day glucose placebo).
MAIN OUTCOME MEASURES:Serum T and DHT were measured and ratio calculated at baseline and after 7 days and 21 days of creatine supplementation (or placebo). Body composition measurements were taken at each time point.
After 7 days of creatine loading, or a further 14 days of creatine maintenance dose, serum T levels did not change. However, levels of DHT increased by 56% after 7 days of creatine loading and remained 40% above baseline after 14 days maintenance (P < 0.001). The ratio of DHT:T also increased by 36% after 7 days creatine supplementation and remained elevated by 22% after the maintenance dose (P < 0.01).
Creatine supplementation may, in part, act through an increased rate of conversion of T to DHT. Further investigation is warranted as a result of the high frequency of individuals using creatine supplementation and the long-term safety of alterations in circulating androgen composition.
STATEMENT OF CLINICAL RELEVANCE: Although creatine is a widely used ergogenic aid, the mechanisms of action are incompletely understood, particularly in relation to dihydrotestosterone, and therefore the long-term clinical safety cannot be guaranteed."The only good is knowledge and the only evil is ignorance." - Socrates
04-02-2013, 12:27 AM
04-07-2013, 04:18 PM
I can't fathom any reason creatine would even be questioned except dumb asses spreading ridiculous broscience about.
04-07-2013, 08:47 PM
04-08-2013, 01:03 PM
04-08-2013, 03:01 PM
It's worth a try, if you've been on beta alanine for a while I would add it to everything you're currently using so you will be able to tell if any difference is made.
04-08-2013, 03:10 PM
In a world full of snake oil, creatine is one of the only supplements not emptying peoples' wallets based on the placebo effect. It actually works. Imagine that.
04-08-2013, 03:19 PM
04-08-2013, 03:22 PM
04-08-2013, 03:26 PM
04-08-2013, 03:32 PM
I was just saying in general its best to assess new ingredients when using them solo. I also encourage people to try both solo to see which ingredient they prefer, I find COP to outperform BA personally, so I wonder if that is the case for many.
04-08-2013, 06:48 PM
04-09-2013, 12:46 PM
04-09-2013, 08:11 PM
Similar Forum Threads
- By Elizabeth0215 in forum Female FitnessReplies: 7Last Post: 09-10-2012, 06:12 PM
- By Y2Jversion1 in forum General ChatReplies: 103Last Post: 06-21-2006, 03:55 PM
- By rampage jackson in forum Nutrition / HealthReplies: 6Last Post: 06-11-2006, 02:03 AM
- By ex_banana-eater in forum Weight LossReplies: 13Last Post: 02-03-2003, 10:02 PM