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Toxic hepatitis in group of 20 male bodybuilders on supplements

Ballesteri

Ballesteri

Member

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Medical Toxicology Research Center, School of Medicine, Mashhad University of Medical Sciences, and Department of Clinical Bacteriology, Ghaem University Hospital, Mashhad, Iran.

Abstract

Dietary supplements have been used for decades for enhancing muscle growth. The harm caused by some of these products is well documented. We investigated and reported toxic hepatitis in 20 male athletes following self-prescribing of a number of dietary supplements which are lesser known. The patients' ages ranged from 24 to 32 with a mean of 28 years. They had taken three kinds of supplements for 1 year including testosterone optimizer agent T Bomb II, a creatine supplement Phosphagen and an amino acid based supplement Cell-Tech. Based on the history, clinical examination, and laboratory findings the cases were diagnosed as toxic hepatitis. After discontinuation of taking the supplements, clinical recovery and improvement of liver function tests were achieved within 30 days. Causality assessment with the CIOMS (Council for International Organization Medical Sciences) scale showed a "possible" grade of causality (+5 points) for these supplements. It can be concluded that these newer anabolic supplements may induce toxic hepatitis. Since the health risks of them may be severe, the use of these kinds of dietary supplements should be discouraged.

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[TABLE="class: outer_label"]
[TR]
[TD]
[TABLE="class: facts_label"]
[TR]
[TD="class: seq_span label_serving, colspan: 3"]Serving Size3Tablets
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_serving, colspan: 3"]Servings Per Container112
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_divider medium, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_heading_l"]Amount Per Serving
[/TD]
[TD="class: seq_span label_heading_r, colspan: 2"]% Daily Value
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_divider narrow, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_ing"]Magnesium(as Magnesium Oxide)
[/TD]
[TD="class: seq_span label_qty"]15mg
[/TD]
[TD="class: seq_span label_dv"]4%
[/TD]
[/TR]
[TR]
[TD="class: line_above seq_span label_ing"]Zinc(as Zinc Aspartate)
[/TD]
[TD="class: line_above seq_span label_qty"]25mg
[/TD]
[TD="class: line_above seq_span label_dv"]167%
[/TD]
[/TR]
[TR]
[TD="class: line_above seq_span label_ing"]Copper(as Copper Gluconate)
[/TD]
[TD="class: line_above seq_span label_qty"]2mg
[/TD]
[TD="class: line_above seq_span label_dv"]100%
[/TD]
[/TR]
[TR]
[TD="class: line_above seq_span label_divider medium, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_ing, colspan: 3"]optimone 5™:
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_divider narrow, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_ing"]Five Phase Hormone Optimizing Blend:
[/TD]
[TD="class: seq_span label_qty"]903mg
[/TD]
[TD="class: seq_span label_dv"]*
[/TD]
[/TR]
[TR]
[TD="class: line_above seq_span label_ing line_indent, colspan: 3"]Tribulus Terrestris (Standardized To 60% Furastanol Saponins And 15% Protodiocin), Fenugreek 4:1 Extract (Seed), Tongkat Ali 20:1 Extract (Root)(Eurycoma Longifolia Jack), Red Clover Extract (40% Isoflavones), Chrysin, Kudzu Root (Pueraria Lobota)(40% Isoflavones), DIM (Diindolymethane), Avena Sativa 10:1 Extract (Aerial Parts), Zinc (As Zinc Aspartate), Pygeum Africanum Extract (25% Total Sterol)(Bark), Stinging Nettle Leaf 4:1 Extract, Beta Sitosterol, Saw Palmetto Berry Extract (90% Total Sterols & Free Fatty Acids), Bioperine® (Black Pepper Extract).
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_divider narrow, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_ing, colspan: 3"]2nd Messenger™ Hormone Amplifiers:
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_divider narrow, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_ing"]Receptor Signal Transduction Blend:
[/TD]
[TD="class: seq_span label_qty"]625mg
[/TD]
[TD="class: seq_span label_dv"]*
[/TD]
[/TR]
[TR]
[TD="class: line_above seq_span label_ing line_indent, colspan: 3"]Flaxseed (Fatty Acid Profile [Linolenic 8.0%, Linoleic 2.5%, Oleic 2.5%]), Glycine, L-Arginine, Magnesium Oxide, Dipotassium Phosphate, DL-Malic Acid, L-Methionine, Cordyceps (Cordyceps Sinensis), NADH.
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_divider medium, colspan: 3"][/TD]
[/TR]
[TR]
[TD="class: seq_span label_notes_sm, colspan: 3"]* Daily Value not established
[/TD]
[/TR]
[/TABLE]
[/TD]
[/TR]
[TR]
[TD]
[TABLE="class: other_label"]
[TR]
[TD="class: seq_span label_title_2, colspan: 3"]Other Ingredients
[/TD]
[/TR]
[TR]
[TD="class: seq_span label_ing_2"]Di-Calcium Phosphate, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silica, White Film Coat Ingredients: (Hypromellose, Hydroxypropyl Cellulose, Polyethylene Glycol, Propylene Glycol, Titanium Dioxide)
[/TD]
[/TR]
[/TABLE]
[/TD]
[/TR]
[/TABLE]
 
Ballesteri said:
Dietary supplements have been used for decades for enhancing muscle growth. The harm caused by some of these products is well documented. We investigated and reported toxic hepatitis in 20 male athletes following self-prescribing of a number of dietary supplements which are lesser known. The patients' ages ranged from 24 to 32 with a mean of 28 years. They had taken three kinds of supplements for 1 year including testosterone optimizer agent T Bomb II, a creatine supplement Phosphagen and an amino acid based supplement Cell-Tech. Based on the history, clinical examination, and laboratory findings the cases were diagnosed as toxic hepatitis. After discontinuation of taking the supplements, clinical recovery and improvement of liver function tests were achieved within 30 days. Causality assessment with the CIOMS (Council for International Organization Medical Sciences) scale showed a "possible" grade of causality (+5 points) for these supplements. It can be concluded that these newer anabolic supplements may induce toxic hepatitis. Since the health risks of them may be severe, the use of these kinds of dietary supplements should be discouraged.

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Medical Toxicology Research Center, School of Medicine, Mashhad University of Medical Sciences, and Department of Clinical Bacteriology, Ghaem University Hospital, Mashhad, Iran.
Click to expand...

Is there a reason you're spamming the supplement section with multiples of this same post?
 
Well if the "bodybuilders" said that's all they were taking, then it must be true
 
Ballesteri said:
Lol no, I thought after Chris223 Eh?, I should break the heading down in more layman friendly fashion
Click to expand...

fair enough. you can delete the other thread, ya know.
 
Congrats probably 90% of AM we all have hepatitis. Why aren't gym goers dying all around the US then? Fats are bad for you, salts bad for you, protein is bad for you, and now herbs and vitamins are bad for you. But take this acetaminophen and drink this diet coke. Really seems like they want us to be obese malnourished TV zombies.

Probably caused by the hooker period blood they put in cell tech to help you gain 10.4 lbs in 1 month !!!!!
 
That's an unnecessary amount of creatine. Like 15 grams if they only used 1 serving of each a day.

Too many other variables. Diet? Numerous other self prescribed supplements not mentioned? Hmm...
 
AngryOldMan said:
American supplements tested bad in a study done in Iran. Nope, no conflict of interest there ;)
Click to expand...

Iran is totally trustworthy. They've never lied about anything

:P
 
Ballesteri said:
Iran has bigger problems to fry than worring about making false studies about some tiny company like mhp:rolleyes:
Click to expand...

I think they would gladly take any opportunity to discredit any American company
 
Ballesteri said:
<img src="http://anabolicminds.com/forum/attachment.php?attachmentid=76389"/>Yes teh grand conspiracy is all falling into place
Click to expand...

Lol!!
 
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