Agmatine, muscle builder or prostate breaker?
- 02-26-2013, 12:28 PM
Moretti RM, Montagnani MM, Sala A, Motta M, Limonta P. Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase. Int J Cancer. 2004 Oct 20;112(1):87-93.
Hassan S, Carraway RE. Involvement of arachidonic acid metabolism and EGF receptor in neurotensin-induced prostate cancer PC3 cell growth. Regul Pept. 2006 Jan 15;133(1-3):105-14.
Ghosh J, Myers CE. Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. Biochem Biophys Res Commun. 1997 Jun 18;235(2):418-23.
Ghosh J. Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase. Biochem Biophys Res Commun. 2003 Jul 25;307(2):342-9.
- 02-26-2013, 12:28 PM
- 02-26-2013, 12:29 PM
02-26-2013, 12:31 PM
02-26-2013, 12:31 PM
02-26-2013, 12:34 PM
Actually carbohydrates do fuel tumor grouth. But ingesting or not carbohydrate is a personal choice. Same for ARA or agmatine
02-26-2013, 12:37 PM
02-26-2013, 12:39 PM
This thread is ironic. On a forum that most are okay with hitting peptides up like candy (IGF).
The Historic PES Legend
02-26-2013, 12:49 PM
"Autopsies in 70-year-old patients show that 46% of males have prostate cancer, but fortunately, it is very slow growing compared to other cancers. About 90% of prostate cancers remain latent over decades. Microscopic foci of adenocarcinoma can be found in 85-90% of men over 80 years of age, which confirms that most men with prostate cancer die from causes unrelated to the malignant tumour."
So while I'm not even close to being convinced that agmatine has anything to do with prostate cancer, you can learn something new in every thread.
02-26-2013, 01:11 PM
Or I'll take it a step further in your logic - lifting weights increases Testosterone, which increases the substrate for estrogen in the male body, which is also implicated in cancer.
Brb, canceling gym membership cause of cancer.
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02-26-2013, 01:49 PM
Anyway, I can't stress enough that this extrapolation of agmatine is nonsensical! Arachidonic acid is an intermediate in agmatine imidazoline signaling....SO WHAT? Arachidonic acid is an intermediate in a million signaling processes. What about all the other net effects of agmatine?
In fact, all the data I see on agmatine shows ANTI-cancer effects. This is because, like any compound, agmatine has mixed roles in the body. And the net effect of these various roles leads to the prevention, not production, of carcinoma.
The above is my own opinion and does not reflect the opinion of PES
02-26-2013, 02:17 PM
I remember as a kid someone making the statement that "if you live long enough you'll die from cancer."
As stated there are millions of 70, 80 and 90 year olds who are now corpses in the ground. If you did autopsies on them you would discover a variety or early to later stage cancers. They just happened to die from something else before the cancer could get them.
Look at all these little kids takin' care of the music biz don't their bus'ness take good care of me...
02-26-2013, 02:34 PM
02-26-2013, 03:17 PM
Thank you cooper for your constructive posts. Much appreciated.
How do you know Rostam is Persian? : )
02-26-2013, 04:29 PM
04-04-2013, 04:57 AM
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