hsk
Active member
I have been using 6-8 grams of Citrulline Malate daily for quite some time now and have found it to be beneficial for increased endurance, improved circulation, and increased NO production among many other benefits. Would there be any benefit or synergy by adding in Ornithine HCL?
Everywhere I looked, I could not seem to find the answer. So I wanted to get some discussion going regarding these two supplements. I found plenty of threads and information regarding L-Citrulline, Citrulline Malate, and L-Ornithine HCL individually, but I could not really find anything with regards to L-Citrulline/Citrulline Malate vs. L-Ornithine HCL and/or pairing of the two together.
From my understanding, Ornithine, Citrulline, and Arginine are the 3 main components of the Urea Cycle. Ornithine is a precursor to Citrulline, which is in turn is a precursor to Arginine. Also Citrulline can convert back to Ornithine as well. I know there are many pre-workout supps that include both Ornithine and Citrulline, but seeing as how Citrulline can convert back to Ornithine as well, would it be redundant to take both? I have spoken to a few knowledgeable people as well as read a few studies, and it would appear that Citrulline seems to be the more useful component of Urea Cycle seeing as how it can increase arginine and help maximize ornithine. And if that is the case, then for those of us who use the higher end dose of 6-8 grams of Citrulline Malate daily, is this enough to maximize Ornithine levels which would in turn make any additional Ornithine supplementation unecessary?
Everywhere I looked, I could not seem to find the answer. So I wanted to get some discussion going regarding these two supplements. I found plenty of threads and information regarding L-Citrulline, Citrulline Malate, and L-Ornithine HCL individually, but I could not really find anything with regards to L-Citrulline/Citrulline Malate vs. L-Ornithine HCL and/or pairing of the two together.
From my understanding, Ornithine, Citrulline, and Arginine are the 3 main components of the Urea Cycle. Ornithine is a precursor to Citrulline, which is in turn is a precursor to Arginine. Also Citrulline can convert back to Ornithine as well. I know there are many pre-workout supps that include both Ornithine and Citrulline, but seeing as how Citrulline can convert back to Ornithine as well, would it be redundant to take both? I have spoken to a few knowledgeable people as well as read a few studies, and it would appear that Citrulline seems to be the more useful component of Urea Cycle seeing as how it can increase arginine and help maximize ornithine. And if that is the case, then for those of us who use the higher end dose of 6-8 grams of Citrulline Malate daily, is this enough to maximize Ornithine levels which would in turn make any additional Ornithine supplementation unecessary?
