Oh woo, awesome. I will be running daa and other natty boosters and want all chances of gyno sides gone since I'm gyno prone.
Dopadex (Or Even "Lights Out" from iForce)+I3C+Magnesium for PRL control
Zinc would also be beneficial, it tends to be absorbed best with the least side effects if in glycinate/arginate, amino acid, or gluconate bound forms
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Team En Vitro
Dopamine agonists, like vitex, negatively regulate adrenal androgen production (1), while promoting LH/FSH secretion from the pituitary in the presence of hyperprolactinemia. In the absence of the latter, DA agonists produce negligable effects in raising serum testosterone, although if prolactin is lowered too much, testosterone will actually decrease (2).
In this (3) en vivo study, Vitex was given to male mice with normal serum prolactin levels. Vitex treatment resulted in a statistically significant decrease in both testosterone and LH. The take-home message is that dopamine agonism should be used only in the presence of hyperprolactinemia. The exact quantity of prolactin required to necessitate dopamine agonism is up for speculation, but human studies have clearly shown only mild (or none) elevations in testosterone, or other testosterone-induced end-points in those with mild hyperprolactinemia (4).
(1) [www] ncbi [dot] nlm [dot] nih [dot] gov/pubmed/11499189
(2) [www]ncbi . nlm . nih.gov/pubmed/10624504Our data suggest a modulation by PRL of adrenal androgen production. DA treatment reduces PRL and serum androgens. It results in a significant clinical improvement in acne and hirsutism.
(3) [www] ncbi . nlm . nih.gov/pubmed/19070148hypoprolactinemia produces a decrease of basal testosterone levels without any alteration of the response of this steroid to hCG.
\Vitex agnus castus (Vac.) extract decreased significantly the LH and testosterone levels. The coadministration of Vac. extract and bromocriptine decreased LH and testosterone.
(4) [www] ncbi. nlm. nih. gov/pubmed/10624504
No relationship between the PRL and other hormone concentrations was found. No changes were noted in the LH, FSH, testosterone, or estradiol concentrations, or in the sperm density and motility after treatment. ... In infertile men who are mildly hyperprolactinemic, bromocriptine administration does not improve semen analysis, although it does normalize the PRL.
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