GDA, Insulin mim and repartitioner

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  1. Sorry, I can't read that post lol. Titrate it down to a few key points and/or questions


  2. Quote Originally Posted by mr.cooper69
    Sorry, I can't read that post lol. Titrate it down to a few key points and/or questions
    Yea. That was a bit crazy. Cliff notes.

    But by inhibiting glucose similar to acarbose. The way I see it put simply is... Creating poo
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  3. Sorry, I can't read that post lol. Titrate it down to a few key points and/or questions

    OK Mr Coopersixtynine... I split question...


    Quote Originally Posted by mr.cooper69 View Post
    A. How can something dispose of blood glucose if its modality is endogenous enzyme inhibition?
    B. Numerous ingredients found in GDAs inhibit digestive enzymes. Virtually every popular GDA on the market has such an ingredient, or multiple.
    C. Of course only complex carbs are affected. Simple carbs are already in a digested form (no enzymes necessary) and ready for absorption.
    I'm confused on what you say in A) and B). it seems you are saying (with A) that Is stupid to inhibit enzyme (I think you are referring to Alpha amilase) and with B) you are saying that many (if not all) GDA's HAS such kind of ingredients..
    Im confused on what you wanted to say. (i'm happy YOU are in this thread)

    Probably is only a language problem and I can't understand what you are saying (Im Italian)

    C ) OK .

  4. Quote Originally Posted by pectus View Post
    OK Mr Coopersixtynine... I split question...




    I'm confused on what you say in A) and B). it seems you are saying (with A) that Is stupid to inhibit enzyme (I think you are referring to Alpha amilase) and with B) you are saying that many (if not all) GDA's HAS such kind of ingredients..
    Im confused on what you wanted to say. (i'm happy YOU are in this thread)

    Probably is only a language problem and I can't understand what you are saying (Im Italian)

    C ) OK .
    No, I do not mean that in a negative sense.

    You need to remember that most "GDAs" are plants with a variety of constituents. A great example is Banaba. Some constituents block enzymatic release; others do indeed reduce blood glucose. What I'm trying to show you is that "GDAs" have mixed activity because no single plant is composed of just one compound. So when you buy a GDA, you're usually buying more than just glucose disposal; you're also buying agents that reduce or delay (reduce in more extreme cases; merely delay at reasonable doses) glucose absorption. Either way, BOTH of these effects serve to allow for the true purpose of GDAs: reduction of insulin release for a given meal.

    Does that make sense? Thanks for your patience.

  5. Quote Originally Posted by mr.cooper69 View Post
    No, I do not mean that in a negative sense.

    You need to remember that most "GDAs" are plants with a variety of constituents. A great example is Banaba. Some constituents block enzymatic release; others do indeed reduce blood glucose. What I'm trying to show you is that "GDAs" have mixed activity because no single plant is composed of just one compound. So when you buy a GDA, you're usually buying more than just glucose disposal; you're also buying agents that reduce or delay (reduce in more extreme cases; merely delay at reasonable doses) glucose absorption. Either way, BOTH of these effects serve to allow for the true purpose of GDAs: reduction of insulin release for a given meal.

    Does that make sense? Thanks for your patience.
    Thanks to YOU to YOUR patience.
    I'll try to re-formulate the next questions i have posted in the big long post.
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  6. Quote Originally Posted by Distilled Water

    "New" 60cap
    Phellodendron (Bark), Crape Mertle (Lagerstroemia Speciosia)(Stem) (Extract)

    750 mg **

    "Old" 90cap
    P-Insulin Engineered Extract from

    Phellodendron

    Tannins Complex Engineered Extract from
    My phones messing up....edit
    Lagerstroemia Speciosa

    700 mg

    Active extracts in bold, notice anything

    EDIT: phones messing up, it's all bold. :-(
    Yeah... So what changed between the old and new bottle?
    Thought it was just count/size.
    Hardcore Purus Labs {Rep}
    Lift the fücking weight from the floor, or leave it on the ground. The thoughts are supposed to be daunting. The pain is meant to be tormenting.

  7. Quote Originally Posted by AaronJP1

    Yeah... So what changed between the old and new bottle?
    Thought it was just count/size.
    More extract in the new one, per serving. Same product though.
    Serious Nutrition Solutions Representative

  8. OK , next question:
    " I do not understand if they act as synergic, agonist, antagonist to INSULIN. If they lower or raise the REAL insulin action.

    if they acts as substitute/complementary of insulin and if it desiderabele to have more or less (real insuline) AND WHEN.

    So if they acts like insulin (in a way), why NOT using straight INSULIN or wait that the endogenous one will appears after a rich glucidic meal?

    This question made me think that probably the key (or one of the keys) is that we USE GDA's BEFORE meal and that
    endogenous insuline appears ONLY when the meal is finished.

  9. Quote Originally Posted by pectus View Post
    OK , next question:" I do not understand if they act as synergic, agonist, antagonist to INSULIN. If they lower or raise the REAL insulin action. if they acts as substitute/complementary of insulin and if it desiderabele to have more or less (real insuline) AND WHEN.So if they acts like insulin (in a way), why NOT using straight INSULIN or wait that the endogenous one will appears after a rich glucidic meal?This question made me think that probably the key (or one of the keys) is that we USE GDA's BEFORE meal and thatendogenous insuline appears ONLY when the meal is finished.
    None of the above, biochemically. They reduce insulin output because:a. they dispose of blood glucose in an insulin-independent fashion (GENERALLY, with few exceptions)b. they block carbs so less insulin is requiredYou use GDAs for health reasons, not body composition reasons. Excessive insulin output is associated with a TON of pathologies; conversely, low insulin levels seem to promote a healthy hormonal atmosphere and longevity. Insulin is a highly anabolic hormone though, so we don't want to kill it, but rather reduce spikes (similar to cortisol). And endogenous insulin is present during the meal as with the GDA-effects of the ingredients.

  10. Hey guys,

    sorry for digging up this old thread but im still super confused about this whole GDA thing.

    So GDAs are supposed to shuttle carbs/glucose into the glycogen stores of our muscles and at the same time keep them away from the fat cells. Well thats at least what it says on the description of my bottle of AP...

    But then again i read that nutrients are non-selectively shuttled to both fat and muscle:

    Quote Originally Posted by Smitty77 View Post
    Because GLUT4 originates in both adipose and muscle tissue, you can see what I mean by non-selectivity.

    So, for however indiscreetly these products serve to aid in muscle growth, you're looking at the same impact on fat as well. Simply put, if you can get swole from GDA utilization, you may be able to get fatter, too.
    (quote is from page 1 of this thread)

    Doesnt this mean GDAs are completely useless if youre cutting? Even counter-productive, since it will be easier for nutrients/carbs to go into fat cells...

    This is so confusing, since so u can find so many positive reviews of people who are using GDAs for cutting...

  11. Quote Originally Posted by Paramount View Post
    Hey guys,

    sorry for digging up this old thread but im still super confused about this whole GDA thing.

    So GDAs are supposed to shuttle carbs/glucose into the glycogen stores of our muscles and at the same time keep them away from the fat cells. Well thats at least what it says on the description of my bottle of AP...

    But then again i read that nutrients are non-selectively shuttled to both fat and muscle:



    (quote is from page 1 of this thread)

    Doesnt this mean GDAs are completely useless if youre cutting? Even counter-productive, since it will be easier for nutrients/carbs to go into fat cells...

    This is so confusing, since so u can find so many positive reviews of people who are using GDAs for cutting...
    Please read, quite literally, the post above yours...

  12. I did read it again now, but it leaves me as wise as before to be honest.

    This whole thing isnt easy if english isnt your first language

    So lets see if i got things right:

    1. GDAs are for health reasons only
    2. They cant be used for body recomp at all, especially not to block carbs from fat cells but shuttle them into muscles
    3. All the people who claim to gain lean mass with GDAs like AP or even claim to gain mass and lose fat at the same time are liars (or its placebo effect...)

    Please correct me if im wrong in any of these...

  13. Quote Originally Posted by Paramount View Post
    I did read it again now, but it leaves me as wise as before to be honest.

    This whole thing isnt easy if english isnt your first language

    So lets see if i got things right:

    1. GDAs are for health reasons only
    2. They cant be used for body recomp at all, especially not to block carbs from fat cells but shuttle them into muscles
    3. All the people who claim to gain lean mass with GDAs like AP or even claim to gain mass and lose fat at the same time are liars (or its placebo effect...)

    Please correct me if im wrong in any of these...
    1. Incorrect. Insulin has a variety of feedback mechanisms in the body, such as blockade of HSL, that prevents fat loss. Reducing insulin will create a more lipolytic environment, even if the carbs are "shuttled" to all tissues.
    2. See above
    3. See above

  14. Ok, i think i got it now, thank you

    Any GDA you would highly recommend if my main goal is cutting without worrying about carbs? (assuming my diet is on spot)

  15. Quote Originally Posted by Paramount View Post
    Ok, i think i got it now, thank you

    Any GDA you would highly recommend if my main goal is cutting without worrying about carbs? (assuming my diet is on spot)
    Right here!! Glycophase for $23 and you also get a free 600g tub of Creatine mono, a free pill box and Agmatine samples
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  16. Quote Originally Posted by Paramount View Post
    Ok, i think i got it now, thank you

    Any GDA you would highly recommend if my main goal is cutting without worrying about carbs? (assuming my diet is on spot)
    You could look into NForce by MAN sports. Definitely underated
    Nutraceutical Innovations
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  17. Quote Originally Posted by Paramount View Post
    Ok, i think i got it now, thank you

    Any GDA you would highly recommend if my main goal is cutting without worrying about carbs? (assuming my diet is on spot)
    Burn 24, recompadrol, glycophase, or AP

  18. coming soon iForce GDA

  19. Ok, i think ill try all of these and see which one works best for me.

    Thanks to everyone, especially to mr.cooper69!

  20. Recompadrol.
    Coop hit the nail on the head.
    ...::: Olympus Labs Athlete & Representative :::...
    Crossfit - DEMIGOD -

  21. It does the job of the insulin for you so your insulin will be more sensitive. That's about the only benefit I've seen.

  22. I vote for Burn24. I'm not 100% on how GDAs work but just anecdotal-ly, I feel like Burn24 has helped me with better optimization of nutrients usage.

  23. Coop do you think certain ingredients like corosolic acid can actually shuttle carbs to muscle instead of fat by translocating glut 4 in skeletal muscle?

  24. Quote Originally Posted by Clemenza View Post
    Coop do you think certain ingredients like corosolic acid can actually shuttle carbs to muscle instead of fat by translocating glut 4 in skeletal muscle?
    Nope. Typically, when you see only muscle mentioned, it's because they simply didn't analyze fat tissue

  25. Quote Originally Posted by hvactech View Post
    You could look into NForce by MAN sports. Definitely underated
    Definitely a ****ty product
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