Supplements to increase mental clarity

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  1. Quote Originally Posted by mr.cooper69 View Post
    Acute focus and activation of the reticular system is quite different from enhancing cholinergic transmission and memory formation
    ok, I googled that **** you just said and I think I understand it. Thanks


  2. Quote Originally Posted by mondata
    I am about as ADD as anyone I know and to top that off have terrible sleep habits. I am trying to finish up my doctorate and am having to take some ridiculous classes. Studying for tests while working 40 hours a week is tough. It seems like the older I get the harder it is to retain information. Long story short what's available (either product or component) that may improve cognitive function (memory, clarity, etc.). I looked at bottled oxygen but I am not sure how long the effects are for. Might be funny going in to take test with a bottle of O2 lol.
    Ginkgo and bacopa work best for mental clarity
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  3. Quote Originally Posted by Quadzilla99 View Post
    ok, I googled that **** you just said and I think I understand it. Thanks
    hahahaha! I was gonna suggest a "mr cooper translation app" for this board....you plug in what he posts, then it gives you a lay-mans terms result. this reminds me of sanford and son, when fred would ask the black police officer to translate what the white police officer said LOL... I am the resident translator of gibberish posting in the anabolic section...but this scientific mumbo jumbo translation is way out of my league

  4. Quote Originally Posted by Quadzilla99 View Post
    I guess ephedrine and caffeine is either not as fancy or just not as effective as the stuff mentioned here? I mean is it considered outdated or is it just not mentioned because its been around so long?

    I took ****loads of that in college and could study like a mofo on it
    I think EC is still the real deal. Throw in some ALCAR or Focus XT and its a mean study stack.

  5. ^^

    Yellow jackets and dymetadrine extreme circa 2001.......

    UNreal......

    -Matt
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  6. Im kinda in the ADD club and Aniracetam was way better for me than piracetam. Ani helped me focus in lower doses, sedated me at higher. Piracetam...helped a bit at first, then made my thoughts race even faster. Ashwagahnda is the shiz, especially for evening hours when you need to unwind. ALCAR is very hit or miss for me, though ALCAR-arginate is treating me very well.

  7. Quote Originally Posted by bioman View Post
    Im kinda in the ADD club and Aniracetam was way better for me than piracetam. Ani helped me focus in lower doses, sedated me at higher. Piracetam...helped a bit at first, then made my thoughts race even faster. Ashwagahnda is the shiz, especially for evening hours when you need to unwind. ALCAR is very hit or miss for me, though ALCAR-arginate is treating me very well.
    Can you elaborate on the Ashwagahnda? Does it have a calming effect like Kava or Phenibut...or is it more like an adaptogen?

    Thanks in advance.

  8. Well that is a problem of mine..ADD since i was a kid...I have found just supplementing with Taurine has helped to be honest,alonf with DAA,Carnitine Fumerate and Erase...Just a good sense of well being.I feel sharper and more focused.Especially at work.

    I was just thinking about all this about a week ago

  9. Quote Originally Posted by Jay888999 View Post
    Well that is a problem of mine..ADD since i was a kid...I have found just supplementing with Taurine has helped to be honest,alonf with DAA,Carnitine Fumerate and Erase...Just a good sense of well being.I feel sharper and more focused.Especially at work.

    I was just thinking about all this about a week ago
    Thank the DAA

  10. Quote Originally Posted by mr.cooper69

    Thank the DAA
    Ive read Taurine as well can help with stimulating the mind with focus and clarity.
    In what way does DAA help? Why would i contribute my statement rto only the DAA?

  11. Quote Originally Posted by Jay888999 View Post
    Ive read Taurine as well can help with stimulating the mind with focus and clarity.In what way does DAA help? Why would i contribute my statement rto only the DAA?
    Taurine will realistically have no effect. Neither will erase or carnitine fumarate. DAA is an NMDA agonist, which shows evidence of increasing cognitive function.

  12. Quote Originally Posted by mr.cooper69
    Taurine will realistically have no effect. Neither will erase or carnitine fumarate. DAA is an NMDA agonist, which shows evidence of increasing cognitive function.
    So then supplementing with this on a reg basis and consistantly can only benefit you,id assume? But being it raises test does that cause a problem with consistant use? Ive heard you say Alcar is great for focus,but that can be used year round?

  13. Quote Originally Posted by Jay888999 View Post
    So then supplementing with this on a reg basis and consistantly can only benefit you,id assume? But being it raises test does that cause a problem with consistant use? Ive heard you say Alcar is great for focus,but that can be used year round?
    I wouldn't extrapolate it that far, as longterm studies are absent. Cycle DAA as you would all supplements. ALCAR can essentially be used year round (I cycle off every 6 months).

  14. Quote Originally Posted by mr.cooper69

    I wouldn't extrapolate it that far, as longterm studies are absent. Cycle DAA as you would all supplements. ALCAR can essentially be used year round (I cycle off every 6 months).
    Excellent..i prefer 2 months on daa and 2 months off.I believe in cycling everything.

    Thnx for the advice man

  15. SNS Focus XT is the best supplement in this area. I have had great results with it. I have yet to try the Stim-Free version.
    I'm Back...

  16. Quote Originally Posted by Clickster
    SNS Focus XT is the best supplement in this area. I have had great results with it. I have yet to try the Stim-Free version.
    You should, the fruit punch flavoring is delicious.
    Serious Nutrition Solutions
    Revolutionizing Sports Nutrition, One Product At A Time
    antihero [@] SeriousNutritionSolutions.com

  17. I like Rhodiola tooAnyone remember the short lived "first order" beta alanine product? It has rhodiola in it and thought it was great!-Matt

  18. Have you tried all natural cognitive enhancers? Some herbs help with blood flow to the brain and have the potential to keep your brain into concentrating on the task at hand, increasing alertness and mental clarity. Taking a good focus supplement can give you the discipline you need to become more productive and eliminate distractive tendencies. Try some of these to help you in your efforts: Choline, phoshotidyle serine, aceytyl L-carnitine, gingko biloba, Vitamin B9 or Folic Acid, DMAE, L-cysteine, and rhodiola. Good luck!

  19. Can we get some good conversation on D-Serine and Sarcosine?

  20. Quote Originally Posted by domore View Post
    Can we get some good conversation on D-Serine and Sarcosine?
    For an acute burst of cognitive function, try the NMDA trio of D-Serine, sarcosine, and DAA along with a potentially synergistic AMPA-based agent: aniracetam.

  21. Quote Originally Posted by mr.cooper69 View Post
    For an acute burst of cognitive function, try the NMDA trio of D-Serine, sarcosine, and DAA along with a potentially synergistic AMPA-based agent: aniracetam.
    acute meaning "short-lived and diminishing effects when used repeatedly"?
    ive used sarco, daa, and ani together for the last few weeks and while they dont do anything bad for me, i havent experienced SUPER-WOW effects, maybe because i didnt have the d-serine...?

  22. Quote Originally Posted by dsohei View Post
    acute meaning "short-lived and diminishing effects when used repeatedly"?
    ive used sarco, daa, and ani together for the last few weeks and while they dont do anything bad for me, i havent experienced SUPER-WOW effects, maybe because i didnt have the d-serine...?
    Short-lived, yes. Diminishing effects, no.

    None of these should give you wow effects. They aren't stimulants/work on the reticular activating system. They should improve functional memory.

  23. Quote Originally Posted by mr.cooper69

    Short-lived, yes. Diminishing effects, no.

    None of these should give you wow effects. They aren't stimulants/work on the reticular activating system. They should improve functional memory.
    My functional memory is usually pretty good, i use noots et al for different effects like increasing energy, clarity, motivation, wit, humor, communication and creativity

  24. Since I started taking the ALCAR (1 g A.M. and 0.5g P.M.) and Bacopa I have noticed a few things. I feel like my 'brain' is more calm and relaxed. Usually I have a million thoughts running through my head 24/7 and while I still do its seems to have slowed down slightly. For me this is obviously a good thing. The biggest thing I have noticed is with sleep. I have slept a good bit better but I CANNOT wake up in the mornings. For the first time ever, I have had to set multiple alarms. I have slept through my first alarm every single morning for about a week now and even slept through my phone alarm one day. I like the sleep but it feels like I am drugged when I wake up. May only take the ALCAR in the A.M. and see if any changes occur.

  25. Quote Originally Posted by mr.cooper69 View Post
    For an acute burst of cognitive function, try the NMDA trio of D-Serine, sarcosine, and DAA along with a potentially synergistic AMPA-based agent: aniracetam.
    Can D-Serine, itself, activate the NMDA receptor? Wouldn't a cascade of effects like--preceding agonism of the AMPA receptor, membrane depolarization, NMDA magnesium displacement, and accompanying binding with glutamate--need to be met prior to agonism?

    So, D-Serine is "limited" by prior AMPA activation (among other criteria)? Could it still lead to over activation of the NMDA receptor? I guess this is something that everyone worries about when messing with the NMDA receptor?

    Now, what about allosterism? So, piracetam (and others) don't directly activate any receptor, but it modulates glutaminergic receptors through allosteric activation. Now, aniracetam has a high affinity binding to the AMPA receptor. Will modulating the AMPA receptor lead to over-activation of the NMDA receptor?

    Alright, I was pretty long winded, but I needed to work through that post to help myself understand.

    So, hypothetically speaking, is it safer (avoiding NMDA excitotoxicity) to modulate the AMPA receptor through the use of -racetams, or to activate the NMDA receptor through the use of D-Serine (and follow the cascade of preceding criteria prior to agonism of the NMDA receptor)?

  26. ^^Bump

  27. I didn't follow certain parts of your post, but no, aniracetam would not potentiate excitotoxicity (there are far more mechanisms in place than basic AMPA modulation). In fact, aniracetam would probably prove neuroprotective to any such effect from the combo.

  28. Quote Originally Posted by mr.cooper69 View Post
    I didn't follow certain parts of your post, but no, aniracetam would not potentiate excitotoxicity (there are far more mechanisms in place than basic AMPA modulation). In fact, aniracetam would probably prove neuroprotective to any such effect from the combo.
    Alright, thanks, Coop. I tried to word it the best I could.

    I'll just ask this question while I do some more reading:

    Can D-Serine or Sarcosine potentiate excitotoxicity?

    I would like to investigate the racetams, D-Serine, Sarcosine, and DAA, but I just don't want to be messing with neuronal death, excitotoxicity, etc.

    They all show great potential as cognitive enhancers, but I would like to read up on their pharmacodynamics and pharmacokinetics. I want to know what the drug does to my body and what my body does to the drug.

  29. Quote Originally Posted by domore View Post
    Alright, thanks, Coop. I tried to word it the best I could.

    I'll just ask this question while I do some more reading:

    Can D-Serine or Sarcosine potentiate excitotoxicity?

    I would like to investigate the racetams, D-Serine, Sarcosine, and DAA, but I just don't want to be messing with neuronal death, excitotoxicity, etc.

    They all show great potential as cognitive enhancers, but I would like to read up on their pharmacodynamics and pharmacokinetics. I want to know what the drug does to my body and what my body does to the drug.
    It is highly unlikely that they would do so unless we are talking about a neuron in vitro. There are influx/efflux control systems in place that go beyond things as simple as co-agonism. The whole neuronal apparatus, including the BBB, is geared to prevent excitoxic insult from oral compounds.

  30. Quote Originally Posted by mr.cooper69 View Post
    It is highly unlikely that they would do so unless we are talking about a neuron in vitro. There are influx/efflux control systems in place that go beyond things as simple as co-agonism. The whole neuronal apparatus, including the BBB, is geared to prevent excitoxic insult from oral compounds.
    "You must spread some Reputation around before giving it to mr.cooper69 again."

    If the BBB will prevent excitoxic insult from oral compounds, when does the fascination with creating compounds with the ability to cross the BBB become a waste of time?

    It seems as if creating a compound with even more ability to have BBB permeability has diminishing return (e.g. Magnesium Threonate vs. Any Chelated Magnesium).

    Do you have any suggested readings that deal with the NMDA and AMPA receptors?
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