Chlorogenic acid (Green Coffee Bean) for fat loss
- 07-10-2012, 12:01 PM
Chlorogenic acid (Green Coffee Bean) for fat loss
The other thread is trashed...
So let's try again.
Thoughts? Feedback?
I read the mechanisms involved. They are largely based on glucose metabolism/modulation (post-prandial). So, would this not work as well for the keto crowd since we don't ingest a bunch of carbs anyway?
I also ran across this this study on adverse homocysteine levels imparted by Chlorogenic Acid http://www.ncbi.nlm.nih.gov/pubmed/11237928A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-10-2012, 12:04 PM
Thank you. There are a couple studies on Svetol which is a caffeine free form of Green Coffee Bean extract that contains a high percentage of chlorogenic acid. Interestingly the human study showed positive weight loss effects in overweight people. But the rat study conducted later did not.
I didn't know that homocysteine thing. Got a reference? -
- 07-10-2012, 12:12 PM
- 07-10-2012, 12:22 PM
- 07-10-2012, 12:35 PM
ALL good haha
A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
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- 07-10-2012, 03:09 PM
i like chlorogenic acid, i dont use more then 500mg of it (1g green coffe bean 50%).
not necessary IMO.
7 oxo works better at 200mg per day. Easily put into a nice topical. However topically youll notice an effect locally rather then all around.
200mg 7 oxo orally is nice as well.
for chlorogenic acid it also effects the 11b HSD1 which happens to be a good thing since its expression is in excess during high stress times. - 07-10-2012, 03:12 PM
- 07-10-2012, 03:19 PM
- 07-10-2012, 03:21 PM
Makes sense. Same logic as "Clenviscerate"
Back OT: Can anyone answer my question?
"""I read the mechanisms involved. They are largely based on glucose metabolism/modulation (post-prandial). So, would this not work as well for the keto crowd since we don't ingest a bunch of carbs anyway?""
A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-10-2012, 03:26 PM
it will still work for a keto crowd due to the effects on cortisol, especially in the begining phase of the ketogenic diet.
im unsure of its affect on PI3K/Akt so i cant answer its effect on insuline secretion as of yet if its function is a purporse of blocked digestion.
If it reduces Akt then you reduce adipogenisis. Stearic acid and other saturated fats increase Akt (similar to the way carb and insulin interact with PI3K/Akt pathway). So if it affect Akt thn yes it will be a positive effect as itll repress adipogenesis in presense of a high fat diet.
But there are also other thinks like the ERK1/2 pathway phosphorylation. so there are many mechanisms that need to be looked at before we can truely see. - 07-10-2012, 03:37 PM
Clen is systemic.
When has chlorogenic acid been shown to reduce cortisol? And in what tissue? The only way it helps at the beginning is that it may get you to ketosis faster is if you are eating carbohydrates. Which nobody does at the start of a Keto diet.
Whacked its not very useful, like you thought, in that circumstance. Unless it has other MOA's, but the latest green coffee Bean extract study that everyone was excited about indicated its primary moa is as a "carb blocker" - 07-10-2012, 03:43 PM
A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-10-2012, 03:53 PM
Originally Posted by Royd The Noyd
- 07-10-2012, 03:56 PM
Originally Posted by Royd The Noyd
http://m.jbc.org/content/281/1/341.full - 07-10-2012, 07:17 PM
Good stuff EBF!
Here is the antithesis of a scientic post but.......
Amazon.com rated the stuff VERY POORLY.A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-10-2012, 09:09 PM
- 07-11-2012, 09:38 AM
A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-11-2012, 10:38 AM
No because they found no decrease in urinary cortisol in the black coffee group. They actually saw an increase. But both groups saw significant statistical fat loss. I don't have the full text though so maybe there is something else in there. It's a weird journal. Not on pubmed or medline.
- 07-11-2012, 10:51 AM
Is urinary decrease or increase necessarily the be all end all "proof' that cortisol levels have been manipultated? Thanks
A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-11-2012, 11:09 AM
- 07-11-2012, 05:35 PM
What about God though?
Just playing, good stuff so far guys, very informative. Subbed to read more later!EvoMuse Products Rep
PM me with any questions! - 07-11-2012, 05:46 PM
- 07-11-2012, 05:53 PM
- 07-11-2012, 06:31 PM
LOL
topicals have their place but this is a whole diff animal as you knowA-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
"The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction" Proverbs 1:7
- 07-11-2012, 06:37 PM
EvoMuse Products Rep
PM me with any questions!
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